scholarly journals Adipokinetic Hormone Receptor Mediates Trehalose Homeostasis to Promote Vitellogenin Uptake by Oocytes in Nilaparvata lugens

2019 ◽  
Vol 9 ◽  
Author(s):  
Kai Lu ◽  
Ying Wang ◽  
Xia Chen ◽  
Xinyu Zhang ◽  
Wenru Li ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Nilaparvata Lugens ◽  
Adipokinetic Hormone

Open conformation of adipokinetic hormone receptor from the malaria mosquito facilitates hormone binding

Peptides ◽  
2011 ◽  
Vol 32 (3) ◽  
pp. 553-559 ◽  
Author(s):  
Grace Mugumbate ◽  
Graham E. Jackson ◽  
David van der Spoel
Keyword(s):  
Hormone Receptor ◽  
Malaria Mosquito ◽  
Hormone Binding ◽  
Adipokinetic Hormone ◽  
Open Conformation

scholarly journals Identification and Functional Analysis of G Protein-Coupled Receptors in 20-Hydroxyecdysone Signaling From the Helicoverpa armigera Genome

2021 ◽  
Vol 9 ◽  
Author(s):  
Yan-Li Li ◽  
Yan-Xue Li ◽  
Xiao-Pei Wang ◽  
Xin-Le Kang ◽  
Ke-Qin Guo ◽  
...  
Keyword(s):  
G Protein ◽  
Helicoverpa Armigera ◽  
Hormone Receptor ◽  
G Protein Coupled Receptors ◽  
Membrane Receptors ◽  
Pest Species ◽  
Metamorphic Stage ◽  
Adipokinetic Hormone ◽  
Helicoverpa Armígera ◽  
G Protein Coupled

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors in animals and humans, which transmit various signals from the extracellular environment into cells. Studies have reported that several GPCRs transmit the same signal; however, the mechanism is unclear. In the present study, we identified all 122 classical GPCRs from the genome of Helicoverpa armigera, a lepidopteran pest species. Twenty-four GPCRs were identified as upregulated at the metamorphic stage by comparing the transcriptomes of the midgut at the metamorphic and feeding stages. Nine of them were confirmed to be upregulated at the metamorphic stage. RNA interference in larvae revealed the prolactin-releasing peptide receptor (PRRPR), smoothened (SMO), adipokinetic hormone receptor (AKHR), and 5-hydroxytryptamine receptor (HTR) are involved in steroid hormone 20-hydroxyecdysone (20E)-promoted pupation. Frizzled 7 (FZD7) is involved in growth, while tachykinin-like peptides receptor 86C (TKR86C) had no effect on growth and pupation. Via these GPCRs, 20E regulated the expression of different genes, respectively, including Pten (encoding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase), FoxO (encoding forkhead box O), BrZ7 (encoding broad isoform Z7), Kr-h1 (encoding Krüppel homolog 1), Wnt (encoding Wingless/Integrated) and cMyc, with hormone receptor 3 (HHR3) as their common regulating target. PRRPR was identified as a new 20E cell membrane receptor using a binding assay. These data suggested that 20E, via different GPCRs, regulates different gene expression to integrate growth and development.

scholarly journals Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori

FEBS Letters ◽  
2009 ◽  
Vol 583 (9) ◽  
pp. 1463-1468 ◽  
Author(s):  
Chenggang Zhu ◽  
Haishan Huang ◽  
Rongsheng Hua ◽  
Guo Li ◽  
Dong Yang ◽  
...  
Keyword(s):  
Bombyx Mori ◽  
Hormone Receptor ◽  
Functional Characterization ◽  
Peptide Ligands ◽  
Adipokinetic Hormone

Adipokinetic hormone enhances CarE ‐mediated chlorpyrifos resistance in the brown planthopper, Nilaparvata lugens

2020 ◽  
Vol 29 (6) ◽  
pp. 511-522
Author(s):  
B. Tang ◽  
Y. Cheng ◽  
Y. Li ◽  
W. Li ◽  
Y. Ma ◽  
...  
Keyword(s):  
Brown Planthopper ◽  
Nilaparvata Lugens ◽  
Adipokinetic Hormone

Adipokinetic hormone regulates cytochrome P450-mediated imidacloprid resistance in the brown planthopper, Nilaparvata lugens

Chemosphere ◽  
2020 ◽  
Vol 259 ◽  
pp. 127490 ◽  
Author(s):  
Bingjie Tang ◽  
Yibei Cheng ◽  
Yimin Li ◽  
Wenru Li ◽  
Ying Ma ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Brown Planthopper ◽  
Nilaparvata Lugens ◽  
Adipokinetic Hormone
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