scholarly journals Daily Intermittent Normobaric Hypoxia Over 2 Weeks Reduces BDNF Plasma Levels in Young Adults – A Randomized Controlled Feasibility Study

2018 ◽  
Vol 9 ◽  
Author(s):  
Andreas Becke ◽  
Patrick Müller ◽  
Milos Dordevic ◽  
Volkmar Lessmann ◽  
Tanja Brigadski ◽  
...  
Keyword(s):  
Young Adults ◽  
Feasibility Study ◽  
Plasma Levels ◽  
Normobaric Hypoxia ◽  
Randomized Controlled ◽  
Intermittent Normobaric Hypoxia

scholarly journals Effects of tai chi chuan on anxiety and sleep quality in young adults: lessons from a randomized controlled feasibility study

2016 ◽  
Vol Volume 8 ◽  
pp. 305-314 ◽  
Author(s):  
Karen Caldwell ◽  
Shawn M Bergman ◽  
Scott Collier ◽  
N. Travis Triplett ◽  
Rebecca Quin ◽  
...  
Keyword(s):  
Young Adults ◽  
Sleep Quality ◽  
Feasibility Study ◽  
Tai Chi ◽  
Tai Chi Chuan ◽  
Randomized Controlled

Peculiarities of psychophysiological adaptation of marine cadets during professional training in marine specialities

2019 ◽  
pp. 19-24 ◽  
Author(s):  
Pavel F. Kiku ◽  
Evgeniy V. Zhovnerchuk ◽  
Irina P. Melnikova ◽  
Natalya I. Izmerovа ◽  
Kseniya M. Sabirova
Keyword(s):  
Professional Training ◽  
Reference Group ◽  
Educational Institution ◽  
Normobaric Hypoxia ◽  
Medical Rehabilitation ◽  
Occupational Training ◽  
Prophylactic Measures ◽  
Study Results ◽  
Intermittent Normobaric Hypoxia ◽  
Emotional Strain

Introduction.Occupational environment and occupational factors determine peculiarities in mastering marine occupations. Some unfavorable occupational educational and ecologic factors appear to cause high level of physical and psychoemotional stress.Objectiveis to study features of adaptation to study during occupational training in marine specialties in cadets of a higher marine educational institution, and to conduct medical and psychological rehabilitation.Material and methods.Examination covered 120 male cadets of 3rd and 4thyears of study: 70 (main group) and 50 (reference group). The age of the cadets was 21±0.4 years. To study characteristics of the cadets’ adaptation, the authors used psychological methods — Spielberger’s State Trait Anxiety Scale and Nemchin’s «Method measuring severity of neuropsychic stress». Statistical analysis was performed with software «Statistica for Windows 10.0».Study results and discussion.After 3 months of sailing, majority of the cadets appeared to be dysadapted. Deep clinical and laboratory studies proved that 39.4% of the examinees were apparently healthy and 60.6% of those had chronic diseases. Thus, a system of medical psychologic rehabilitation was designed, comprising primary and secondary prophylaxis methods. One of these prevention methods is a recovery complex of measures with intermittent normobaric hypoxia modified by us. The authors determined optimal regime of using intermittent normobaric hypoxia combined with medical rehabilitation.Conclusions.Adaptational state in cadets of high marine educational institution during professional training in marine occupations is characterized by increased psycho-emotional strain, anxiety and observed in 57.3% of the examinees. Findings are that after 3 months of sailing, majority of the cadets are dysadapted. To prevent morbidity and preserve health, the authors suggested a system of medical and psychologic rehabilitation including intermittent normobaric hypoxia with rehabilitation medical complex. The medical and prophylactic measures help to solve problems of psycho-emotional stress, lower morbidity parameters, prevent dysadaptation disorders, relieve functional overstrain. That preserves and improves the cadets’ health and forms an important stage in prevention of mental and behavioral disorders related to work.

Efficacy and Impact of an mHealth Intervention to promote Mental Wellness for American Indian and Alaska Native Teens and Young Adults: A Randomized Controlled Trial of the BRAVE Study (Preprint)

2020 ◽  
Author(s):  
Stephanie Craig Rushing ◽  
Allyson Kelley ◽  
Sheana Bull ◽  
David Stephens ◽  
Julia Wrobel ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Young Adults ◽  
Alaska Native ◽  
Help Seeking ◽  
Culturally Relevant ◽  
Controlled Trial ◽  
Text Message ◽  
Text Messages ◽  
Randomized Controlled ◽  
Mental Wellness

BACKGROUND Culturally-relevant interventions are needed to help American Indian and Alaska Native (AI/AN) teens and young adults navigate common risky situations involving family and friends, including drug and alcohol misuse, dating violence, and suicidality. We R Native – a multimedia health resource for Native teens and young adults – designed an intervention for Native youth, delivered via text message, that includes role model videos, mental wellness strategies, and links to culturally-relevant resources (hotlines, chat-lines, websites, etc.) and social support. OBJECTIVE This study aims to test the efficacy of BRAVE to improve participant’s physical, mental, and spiritual health, their use of mental wellness strategies, their help-seeking skills, and associated factors, including cultural resilience, identity, and cultural pride. METHODS The randomized controlled trial was carried out by the Northwest Portland Area Indian Health Board and the mHealth Impact Lab. The team recruited 2,334 AI/AN teens and young adults nationwide (15-24 years old) via social media channels and text message and enrolled 1,044 to participate. AI/AN teens and young adults enrolled in the study received either: 8 weeks of BRAVE text messages designed to improve mental health, help-seeking skills, and cultural resilience; or 8 weeks of STEM text messages, designed to elevate and re-affirm Native voices in science, technology, engineering, math and medicine (STEM); and then received the other set of messages. Primary and secondary outcomes were tested using linear mixed-effect models and linear regressions. RESULTS A total of 833 AI/AN teens and young adults were included in the analysis. Individuals in the BRAVE and STEM arms showed significant positive trends over the course of the study for all primary outcomes except cultural identity and help seeking behavior. Mean scores were significantly different for health (P<.001), resilience (P<.001), negative coping (P=.027), positive coping (P<.001), self-efficacy (P=.021), and self-esteem (P<.001). Changes in help-seeking self-efficacy were significant for those exhibiting risky behavior at baseline to exit (P=.01). Those who reported positive coping scores at baseline also reported better health on average, but no difference in risky drug and alcohol use (P<.001). The number of participants that used text messages to help themselves increased from 69% at 3-months (427/618) to 75% at 8-months (381/501) (P<.001). Similarly, the number of participants that used text messages to help a friend or family member increased from 22% at 3-months (138/616) to 55% at 8-months (272/498). CONCLUSIONS This is the first nationwide randomized controlled trial for AI/AN teens and young adults to test the efficacy of an mHealth intervention on mental wellness. The findings suggest that culturally-relevant multimedia, mHealth interventions can improve help-seeking behavior. Lessons learned from this study may help other AI/AN-serving organizations, prevention programs, policymakers, researchers, and educators as they support the next generation of AI/AN change-makers.

Promoting Career Design in Youth and Young Adults with ASD: A Feasibility Study

2021 ◽  
Author(s):  
Evan E. Dean ◽  
Mayumi Hagiwara ◽  
Karrie A. Shogren ◽  
Michael L. Wehmeyer ◽  
Jennifer Shrum
Keyword(s):  
Young Adults ◽  
Feasibility Study ◽  
Youth And Young Adults ◽  
Adults With Asd ◽  
Young Adults With Asd

scholarly journals Standard Care Versus Awake Prone Position in Adult Nonintubated Patients With Acute Hypoxemic Respiratory Failure Secondary to COVID-19 Infection—A Multicenter Feasibility Randomized Controlled Trial

2021 ◽  
pp. 088506662110144
Author(s):  
Devachandran Jayakumar ◽  
Pratheema Ramachandran, DNB ◽  
Ebenezer Rabindrarajan, DNB ◽  
Bharath Kumar Tirupakuzhi Vijayaraghavan, MD ◽  
Nagarajan Ramakrishnan, AB ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Prone Position ◽  
Feasibility Study ◽  
Standard Care ◽  
Controlled Trial ◽  
Prone Positioning ◽  
Hypoxemic Respiratory Failure ◽  
Randomized Controlled ◽  
Significant Difference ◽  
Hypoxic Respiratory Failure

Rationale: The feasibility and safety of awake prone positioning and its impact on outcomes in non-intubated patients with acute respiratory distress syndrome secondary to COVID-19 is unknown. Results of the observational studies published during this pandemic have been conflicting. In this context, we conducted a multi-center, parallel group, randomized controlled feasibility study on awake prone positioning in non-intubated patients with COVID-19 pneumonia requiring supplemental oxygen. Methods: 60 patients with acute hypoxic respiratory failure secondary to COVID-19 pneumonia requiring 4 or more liters of oxygen to maintain a saturation of ≥92% were recruited in this study. Thirty patients each were randomized to either standard care or awake prone group. Patients randomized to the prone group were encouraged to self-prone for at least 6 hours a day. The primary outcome was the proportion of patients adhering to the protocol in each group. Results: In the prone group, 43% (13 out of 30) of patients were able to self-prone for 6 or more hours a day. In the supine group, 47% (14 out of 30) were completely supine and 53% spent some hours in the prone position, but none exceeded 6 hours. There was no significant difference in any of the secondary outcomes between the 2 groups and there were no adverse events. Conclusions: Awake prone positioning in non-intubated patients with acute hypoxic respiratory failure is feasible and safe under clinical trial conditions. The results of our feasibility study will potentially help in the design of larger definitive trials to address this key knowledge gap.

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