scholarly journals Hemodynamic and Metabolic Assessment of Neonates With Punctate White Matter Lesions Using Phase-Contrast MRI and T2-Relaxation-Under-Spin-Tagging (TRUST) MRI

2018 ◽  
Vol 9 ◽  
Author(s):  
Ying Qi ◽  
Peiying Liu ◽  
Zixuan Lin ◽  
Hanzhang Lu ◽  
Xiaoming Wang
Keyword(s):  
White Matter ◽  
Phase Contrast ◽  
White Matter Lesions ◽  
T2 Relaxation ◽  
Phase Contrast Mri ◽  
Spin Tagging

scholarly journals Vessel-specific quantification of blood oxygenation with T2 -relaxation-under-phase-contrast MRI

2013 ◽  
Vol 71 (3) ◽  
pp. 978-989 ◽  
Author(s):  
Lisa C. Krishnamurthy ◽  
Peiying Liu ◽  
Yulin Ge ◽  
Hanzhang Lu
Keyword(s):  
Phase Contrast ◽  
Blood Oxygenation ◽  
T2 Relaxation ◽  
Phase Contrast Mri

scholarly journals Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study

2020 ◽  
pp. 0271678X2092710
Author(s):  
Soroush H Pahlavian ◽  
Xinhui Wang ◽  
Samantha Ma ◽  
Hong Zheng ◽  
Marlena Casey ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cognitive Impairment ◽  
White Matter ◽  
Cognitive Performance ◽  
Phase Contrast ◽  
White Matter Hyperintensity ◽  
Elderly Subjects ◽  
Mean Flow ◽  
Phase Contrast Mri ◽  
Microvascular Damage

Increased cerebroarterial pulsations are thought to be contributing factors in microvascular damage and cognitive impairment. In this study, we assessed the utility of two-dimensional (2D) phase-contrast MRI (PC-MRI) in quantifying cerebroarterial pulsations and evaluated the associations of pulsatile and non-pulsatile hemodynamic measures with cognitive performance and white matter hyperintensities (WMH). Neurocognitive assessments on 50 elderly subjects were performed using clinical dementia rating (CDR) and Montreal cognitive assessment (MoCA). An electrocardiogram-gated 2D PC-MRI sequence was used to calculate mean flow rate, pulsatility index (PI), and resistivity index (RI) of the internal carotid artery. For each subject, whole brain global cerebral blood flow (gCBF) and relative WMH volume were also quantified. Elevated RI was significantly associated with reduced cognitive performance quantified using MoCA ( p =  0.04) and global CDR ( p =  0.02). PI and RI were both significantly associated with relative WMH volume ( p =  0.01, p <  0.01, respectively). However, non-pulsatile hemodynamic measures were not associated with cognitive impairment or relative WMH volume. This study showed that the cerebroarterial pulsatile measures obtained using PC-MRI have stronger association with the measures of cognitive impairment compared to global blood flow measurement and as such, might be useful as potential biomarkers of cerebrovascular dysfunction in preclinical populations.

Author response for "White matter lesions in multiple sclerosis are enriched for CD20 dim CD8 + tissue‐resident memory T cells"

2020 ◽  
Author(s):  
Cheng‐Chih Hsiao ◽  
Nina L. Fransen ◽  
Aletta M.R. den Bosch ◽  
Kim I.M. Brandwijk ◽  
Inge Huitinga ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
White Matter ◽  
Memory T Cells ◽  
White Matter Lesions ◽  
Author Response ◽  
Resident Memory T Cells

A phase-contrast MRI study of physiologic cerebral venous flow

2009 ◽  
Author(s):  
Souraya Stoquart-ElSankari ◽  
Pierre Lehmann ◽  
Agnès Villette ◽  
Marek Czosnyka ◽  
Marc-Etienne Meyer ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Phase Contrast Mri ◽  
Venous Flow ◽  
Mri Study
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