scholarly journals Human Milk and Donkey Milk, Compared to Cow Milk, Reduce Inflammatory Mediators and Modulate Glucose and Lipid Metabolism, Acting on Mitochondrial Function and Oleylethanolamide Levels in Rat Skeletal Muscle

2018 ◽  
Vol 9 ◽  
Author(s):  
Giovanna Trinchese ◽  
Gina Cavaliere ◽  
Chiara De Filippo ◽  
Serena Aceto ◽  
Marina Prisco ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lipid Metabolism ◽  
Human Milk ◽  
Mitochondrial Function ◽  
Inflammatory Mediators ◽  
Cow Milk ◽  
Donkey Milk ◽  
Rat Skeletal Muscle ◽  
Glucose And Lipid Metabolism

1878-P: The Role and Potential Mechanism of LncRNA Gm15441 in Skeletal Muscle Glucose and Lipid Metabolism

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1878-P
Author(s):  
LIANGHUI YOU ◽  
YU ZENG ◽  
NAN GU ◽  
CHENBO JI
Keyword(s):  
Skeletal Muscle ◽  
Lipid Metabolism ◽  
Potential Mechanism ◽  
Glucose And Lipid Metabolism

scholarly journals Vitamins in Human and Donkey Milk: Functional and Nutritional Role

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1509
Author(s):  
Silvia Vincenzetti ◽  
Giuseppe Santini ◽  
Valeria Polzonetti ◽  
Stefania Pucciarelli ◽  
Yulia Klimanova ◽  
...  
Keyword(s):  
Human Milk ◽  
Dairy Cows ◽  
Mammalian Species ◽  
The Elderly ◽  
Health Impact ◽  
Cow Milk ◽  
Donkey Milk ◽  
Positive Health ◽  
Vitamin Status ◽  
Fat Soluble Vitamins

Background: Whole milk is a good source of all the nutrients, and it also contains a sufficient number of vitamins to permit regular the growth of the neonate. Dairy cow milk can create allergy in infants less than 12 months old because of the high caseins and β-lactoglobulin content. In these circumstances, donkey milk can represent a good replacement for dairy cows’ milk in children affected by Cow Milk Protein Allergy (CMPA) because of its close chemical composition with human milk, mainly due to its low protein and low mineral content. Milk vitamin content is highly variable among mammalian species and it is strictly correlated with the vitamin status and the diet administered to the mother. Fat-soluble vitamins content in donkey milk is, on average, lower compared to ruminants’ milk, while vitamin C content determined in donkey milk is higher compared to dairy cows’ milk, showing a great similarity with human milk. In donkey milk, the content of vitamins of the B-complex such as thiamine, riboflavin, niacin, pyridoxine, and folic acid is higher compared to human milk. The use of donkey milk as a new functional food must be further evaluated in interdisciplinary clinical trials in which pediatricians, dietitians, and food scientists must be involved to deepen the knowledge about the positive health impact of donkey milk in different sensitive people, especially children and the elderly.

scholarly journals Human, donkey and cow milk differently affects insulin sensitivity by modulating skeletal muscle mitochondrial function, efficiency and dynamics

2016 ◽  
Vol 1857 ◽  
pp. e100-e101
Author(s):  
Giovanna Trinchese ◽  
Gina Cavaliere ◽  
Chiara De Filippo ◽  
Anna De Angelis ◽  
Antonio Della Gatta ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Insulin Sensitivity ◽  
Mitochondrial Function ◽  
Cow Milk

scholarly journals Sudachitin, a polymethoxylated flavone, improves glucose and lipid metabolism by increasing mitochondrial biogenesis in skeletal muscle

2014 ◽  
Vol 11 (1) ◽  
pp. 32 ◽  
Author(s):  
Rie Tsutsumi ◽  
Tomomi Yoshida ◽  
Yoshitaka Nii ◽  
Naoki Okahisa ◽  
Shinya Iwata ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lipid Metabolism ◽  
Mitochondrial Biogenesis ◽  
Glucose And Lipid Metabolism

scholarly journals siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

2006 ◽  
Vol 4 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Karim Bouzakri ◽  
Anna Zachrisson ◽  
Lubna Al-Khalili ◽  
Bei B. Zhang ◽  
Heikki A. Koistinen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lipid Metabolism ◽  
Gene Silencing ◽  
Human Skeletal Muscle ◽  
Glucose And Lipid Metabolism

scholarly journals The Roots ofAtractylodes macrocephalaKoidzumi Enhanced Glucose and Lipid Metabolism in C2C12 Myotubes via Mitochondrial Regulation

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Mi Young Song ◽  
Seok Yong Kang ◽  
Tae Woo Oh ◽  
Rethineswaran Vinoth Kumar ◽  
Hyo Won Jung ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Lipid Metabolism ◽  
Mitochondrial Function ◽  
Weight Control ◽  
Glucose Consumption ◽  
C2c12 Myotubes ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Nuclear Respiratory Factor ◽  
Glucose And Lipid Metabolism

The root ofAtractylodes macrocephalaKoidzumi (Atractylodis Rhizoma Alba, ARA) is a Traditional Korean Medicine and has been commonly used for weight control. Mitochondrial dysfunction appears to be a key contributor to insulin resistance, and therefore mitochondrial targeting drugs represent an important potential strategy for the treatment of insulin resistance and obesity. In this study, the authors investigated the regulatory effects of ARA on mitochondrial function with respect to the stimulation of glucose and lipid metabolism in C2C12 myotubes. After differentiating C2C12 myotubes, cells were treated with or without different concentrations (0.2, 0.5, and 1.0 mg/mL) of ARA extract. ARA extract significantly increased the expression of peroxisome proliferator-activated receptor coactivator 1 alpha (PGC1α) and the downregulations of its targets, nuclear respiratory factor-1 (NRF-1), transcription factor A (TFAM), and total ATP content in C2C12 myotubes. ARA extract also increased the expressions of PGC1αactivator and of the metabolic sensors, AMP-activated protein kinase (AMPK), and acetyl-CoA carboxylase and sirtuin (SIRT) 1. Furthermore, it significantly increased glucose uptake by enhancing glucose consumption and subsequently decreased FFA contents and increased carnitine palmitoyltransferase (CPT) 1b expression. Our study indicates that ARA has a potential for stimulating mitochondrial function and energy metabolism in muscle.

scholarly journals Effects of Exposure to a 128-mT Static Magnetic Field on Glucose and Lipid Metabolism in Serum and Skeletal Muscle of Rats

2010 ◽  
Vol 41 (5) ◽  
pp. 309-314 ◽  
Author(s):  
Miryam Elferchichi ◽  
Jacques Mercier ◽  
Marjorie Coisy-Quivy ◽  
Lore Metz ◽  
Anne-Dominique Lajoix ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Skeletal Muscle ◽  
Lipid Metabolism ◽  
Static Magnetic Field ◽  
Glucose And Lipid Metabolism

scholarly journals Effect of electrical stimulation-induced resistance exercise on mitochondrial fission and fusion proteins in rat skeletal muscle

2015 ◽  
Vol 40 (11) ◽  
pp. 1137-1142 ◽  
Author(s):  
Yu Kitaoka ◽  
Riki Ogasawara ◽  
Yuki Tamura ◽  
Satoshi Fujita ◽  
Hideo Hatta
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Resistance Exercise ◽  
Mitochondrial Function ◽  
Muscle Protein ◽  
Mitochondrial Dynamics ◽  
Muscle Protein Synthesis ◽  
Mitochondrial Fission ◽  
Dynamic Networks ◽  
Rat Skeletal Muscle

It is well known that resistance exercise increases muscle protein synthesis and muscle strength. However, little is known about the effect of resistance exercise on mitochondrial dynamics, which is coupled with mitochondrial function. In skeletal muscle, mitochondria exist as dynamic networks that are continuously remodeling through fusion and fission. The purpose of this study was to investigate the effect of acute and chronic resistance exercise, which induces muscle hypertrophy, on the expression of proteins related to mitochondrial dynamics in rat skeletal muscle. Resistance exercise consisted of maximum isometric contraction, which was induced by percutaneous electrical stimulation of the gastrocnemius muscle. Our results revealed no change in levels of proteins that regulate mitochondrial fission (Fis1 and Drp1) or fusion (Opa1, Mfn1, and Mfn2) over the 24-h period following acute resistance exercise. Phosphorylation of Drp1 at Ser616 was increased immediately after exercise (P < 0.01). Four weeks of resistance training (3 times/week) increased Mfn1 (P < 0.01), Mfn2 (P < 0.05), and Opa1 (P < 0.01) protein levels without altering mitochondrial oxidative phosphorylation proteins. These observations suggest that resistance exercise has little effect on mitochondrial biogenesis but alters the expression of proteins involved in mitochondrial fusion and fission, which may contribute to mitochondrial quality control and improved mitochondrial function.

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