scholarly journals Functionalized Surface Geometries Induce: “Bone: Formation by Autoinduction”

2018 ◽  
Vol 8 ◽  
Author(s):  
Ugo Ripamonti
Author(s):  
U. Ripamonti ◽  
P.W. Richter ◽  
R.W.N. Nilen ◽  
L.N. Ramoshebi ◽  
L. Renton ◽  
...  

2003 ◽  
Vol 82 (4) ◽  
pp. 293-297 ◽  
Author(s):  
R.B. Rutherford ◽  
P. Racenis ◽  
S. Fatherazi ◽  
K. Izutsu

BMPs are a family of pleiotropic signaling molecules involved at various stages in the formation of bones and teeth. In addition, recombinant BMP can induce bone and dentin regeneration when applied directly to adult tissues. We have shown that fibroblasts transduced ex vivo by BMP cDNA delivered by recombinant adenoviruses induce bone formation and convert to osteoblasts upon implantation in vivo. To determine if this osteogenic capacity was limited to fibroblasts, we found that BMP-7-transduced human oral keratinocyte cells (HOKC) also formed ectopic bone. The ossicles formed by the BMP-7-transduced HOKC were smaller and more dense than those formed by BMP-7-transduced human gingival fibroblasts (HGF). Implanted HOKC were localized adjacent to the developing bone by immunocytochemical detection of keratin expression. However, no bone-like tissue formed when HOKC were implanted into diffusion chambers in vivo. We conclude that BMP-transduced HOKC secrete BMP and form bone in vivo but, unlike BMP-transduced HGF, do not transdifferentiate to osteoblasts.


1997 ◽  
Vol 61 (2) ◽  
pp. 165-167 ◽  
Author(s):  
K. H. Wlodarski ◽  
P. K. Wlodarski

1999 ◽  
Vol 65 (5) ◽  
pp. 414-415 ◽  
Author(s):  
GianFranco Caselli ◽  
Simonetta Fiorentino ◽  
Mara Riminucci ◽  
Alessandro Corsi ◽  
Paolo Bianco

2017 ◽  
Vol 264 ◽  
pp. 29-32
Author(s):  
Nurul Farhana Ibrahim ◽  
Hasmaliza Mohamad ◽  
Siti Noor Fazliah Mohd Noor ◽  
Nurazreena Ahmad

Hydroxyapatite (HA) has similar constituent with natural bone mineral and is able to evoke apatite formation on the bone interface. Similarly, bioactive glass (BG) such as 45S5 has the ability to induce bone formation when exposed to physiological environment. However, both materials have drawbacks in mechanical properties such as brittleness and low compressive strength. Hence, HA-BG composite has potential for enhance properties. The current work aims to assess the effects of BG addition in HA system focusing on mechanical properties.


1992 ◽  
Vol 24 (5) ◽  
pp. 667-679 ◽  
Author(s):  
E. Lopez ◽  
B. Vidal ◽  
S. Berland ◽  
S. Camprasse ◽  
G. Camprasse ◽  
...  

2008 ◽  
Vol 366 (2) ◽  
pp. 483-488 ◽  
Author(s):  
Morten A. Karsdal ◽  
Anita V. Neutzsky-Wulff ◽  
Morten H. Dziegiel ◽  
Claus Christiansen ◽  
Kim Henriksen

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