scholarly journals Intervertebral Disc Swelling Demonstrated by 3D and Water Content Magnetic Resonance Analyses after a 3-Day Dry Immersion Simulating Microgravity

2016 ◽  
Vol 7 ◽  
Author(s):  
Loïc Treffel ◽  
Karen Mkhitaryan ◽  
Stéphane Gellee ◽  
Guillemette Gauquelin-Koch ◽  
Claude Gharib ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Intervertebral Disc ◽  
Water Content ◽  
Dry Immersion

scholarly journals DI-5-Cuffs: Lumbar Intervertebral Disc Proteoglycan and Water Content Changes in Humans after Five Days of Dry Immersion to Simulate Microgravity

2020 ◽  
Vol 21 (11) ◽  
pp. 3748
Author(s):  
Loïc Treffel ◽  
Nastassia Navasiolava ◽  
Karen Mkhitaryan ◽  
Emmanuelle Jouan ◽  
Kathryn Zuj ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Water Content ◽  
T2 Mapping ◽  
Lumbar Region ◽  
Gravitational Unloading ◽  
Lumbar Intervertebral Disc ◽  
Dry Immersion ◽  
Disc Herniations ◽  
Proteoglycan Content ◽  
Underlying Mechanisms

Most astronauts experience back pain after spaceflight, primarily located in the lumbar region. Intervertebral disc herniations have been observed after real and simulated microgravity. Spinal deconditioning after exposure to microgravity has been described, but the underlying mechanisms are not well understood. The dry immersion (DI) model of microgravity was used with eighteen male volunteers. Half of the participants wore thigh cuffs as a potential countermeasure. The spinal changes and intervertebral disc (IVD) content changes were investigated using magnetic resonance imaging (MRI) analyses with T1-T2 mapping sequences. IVD water content was estimated by the apparent diffusion coefficient (ADC), with proteoglycan content measured using MRI T1-mapping sequences centered in the nucleus pulposus. The use of thigh cuffs had no effect on any of the spinal variables measured. There was significant spinal lengthening for all of the subjects. The ADC and IVD proteoglycan content both increased significantly with DI (7.34 ± 2.23% and 10.09 ± 1.39%, respectively; mean ± standard deviation), p < 0.05). The ADC changes suggest dynamic and rapid water diffusion inside IVDs, linked to gravitational unloading. Further investigation is needed to determine whether similar changes occur in the cervical IVDs. A better understanding of the mechanisms involved in spinal deconditioning with spaceflight would assist in the development of alternative countermeasures to prevent IVD herniation.

Magnetic Resonance Imaging Spatial and Time Study of Lung Water Content in Newborn Lamb: Methods and Preliminary Results

2008 ◽  
Vol 43 (6) ◽  
pp. 470-480 ◽  
Author(s):  
Romain Viard ◽  
Pierre Tourneux ◽  
Laurent Storme ◽  
Julie-Marie Girard ◽  
Nacim Betrouni ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Water Content ◽  
Time Study ◽  
Resonance Imaging ◽  
Lung Water ◽  
Newborn Lamb ◽  
Preliminary Results ◽  
Lung Water Content

Agreement between magnetic resonance imaging, myelography, and surgery for detecting recurrent, thoracolumbar intervertebral disc extrusion in dogs

2013 ◽  
Vol 26 (01) ◽  
pp. 12-18 ◽  
Author(s):  
B. A. Brisson ◽  
S. G. Nykamp ◽  
D. Reynolds
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Intervertebral Disc ◽  
Interobserver Agreement ◽  
Surgical Decompression ◽  
Diagnostic Methods ◽  
Resonance Imaging ◽  
Disc Disease ◽  
Recurrent Lesion ◽  
Magnetic Resonance Imaging Mri

Summary Objectives: Although magnetic resonance imaging (MRI) is reported to be superior to myelography to determine the location and site of first time disc herniation, comparison of these diagnostic methods in cases of recurrent intervertebral disc disease (IVD) herniation after a first surgery has not been evaluated. The objective was to compare the diagnostic accuracy of MRI and myelography in a series of dogs undergoing repeat surgical decompression for recurrent IVD extrusion when compared to the gold standard of surgery. Methods: Ten dogs with recurrent IVD herniation underwent MRI and myelography followed by surgical decompression. Three observers reviewed the images to determine the site and side of the first surgery and the recurrent lesion. Agreement was determined by calculating a kappa (κ) score. Results: Substantial interobserver agreement was noted for recurrent lesion site using MRI and myelography (κ = 0.77 vs. 0.73) and when comparing MRI and myelography to the reported surgical site (κ = 0.73 vs. 0.67). Interobserver agreement was greater with MRI for circumferential location compared to myelography (κ = 0.76 vs. 0.43), similar to what was found when comparing to surgical side (κ = 0.82 vs. 0.49). The previous surgical site in this study had no effect on ability to identify the new lesion. Clinical significance: Despite the limitations of MRI, there was greater agreement between observers using MRI for both the recurrent and first lesion.

Changes in Soil Water Content Resulting from Ricinus Root Uptake Monitored by Magnetic Resonance Imaging

2008 ◽  
Vol 7 (3) ◽  
pp. 1010-1017 ◽  
Author(s):  
A. Pohlmeier ◽  
A. Oros-Peusquens ◽  
M. Javaux ◽  
M. I. Menzel ◽  
J. Vanderborght ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Water Content ◽  
Soil Water ◽  
Soil Water Content ◽  
Root Uptake ◽  
Resonance Imaging
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