scholarly journals From gene to protein—experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension

2014 ◽  
Vol 5 ◽  
Author(s):  
Sheila K. Patel ◽  
Elena Velkoska ◽  
Melanie Freeman ◽  
Bryan Wai ◽  
Terase F. Lancefield ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Blood Pressure Control ◽  
Clinical Studies ◽  
Pressure Control

scholarly journals Sex, Oxidative Stress, and Hypertension: Insights From Animal Models

Physiology ◽  
2019 ◽  
Vol 34 (3) ◽  
pp. 178-188 ◽  
Author(s):  
Jane F. Reckelhoff ◽  
Damian G. Romero ◽  
Licy L. Yanes Cardozo
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Animal Models ◽  
Blood Pressure Control ◽  
Clinical Studies ◽  
Pressure Control ◽  
Pharmacological Intervention ◽  
Preclinical Studies ◽  
Initial Development ◽  
And Oxidative Stress

One of the mechanisms responsible for blood pressure (BP) regulation is thought to be oxidative stress. In this review, we highlight preclinical studies that strongly support a role for oxidative stress in development and maintenance of hypertension in male animals, based on depressor responses to antioxidants, particularly tempol and apocynin. In females, oxidative stress seems to be important in the initial development of hypertension. However, whether maintenance of hypertension in females is mediated by oxidative stress is not clear. In clinical studies, pharmacological intervention to reduce BP with antioxidants has conflicting results, mostly negative. This review will discuss the uncertainties regarding blood pressure control and oxidative stress and potential reasons for these outcomes.

Pharmacological Interactions on Blood Pressure Control in Arterial Hypertension, An Issue not to be Overlooked

2016 ◽  
Vol 15 (3) ◽  
pp. 210-223
Author(s):  
Michele M. Ciulla ◽  
Chiara Benfenati ◽  
Enrico Gallazzi ◽  
Patrizia Vivona ◽  
Roberto Meazza ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Pharmacological Interactions

scholarly journals Use of Lipid‐Lowering Drugs and Blood Pressure Control in Patients With Arterial Hypertension

2002 ◽  
Vol 4 (4) ◽  
pp. 277-285 ◽  
Author(s):  
Claudio Borghi ◽  
Ada Dormi ◽  
Maddalena Veronesi ◽  
Vincenzo Immordino ◽  
Ettore Ambrosioni
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Lipid Lowering ◽  
Lipid Lowering Drugs

scholarly journals Correction of over-dosed insulin in a type-2- diabetic led to a better control of glycemia and arterial hypertension: a case report

2021 ◽  
Author(s):  
Abimbola Abobarin-Adeagbo ◽  
Torsten Kraya ◽  
Matthias Girndt ◽  
Rainer Ullrich Pliquett
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Insulin Therapy ◽  
Blood Pressure Control ◽  
Hemoglobin A1c ◽  
Pressure Control ◽  
Hormonal Stimulation ◽  
The Poor ◽  
Type 2 Diabetic

Abstract Background:An association between hypoglycemia and arterial hypertension has been proposed. Here, for the first time, we report a case of a chronically over-dosed insulin therapy with uncontrolled hypertension, which improved after insulin-dose reduction.Case Presentation: A 73-year-old, male type-2 diabetic of Caucasian ethnicity was hospitalized for uncontrolled arterial hypertension and weakness. Prior to hospitalization, a fixed-dose insulin therapy (160 units per day) and antihypertensive medication with urapidile, valsartan and bisoprolol were prescribed. Hemoglobin A1c was 11.2%, symptomatic hypoglycemic episodes were not reported. During hospitalization, metformin, empagliflozin, and dulaglutide (1.5 mg per week) were added to insulin. Conventional insulin therapy was switched to an intensified insulin therapy with a cumulative daily dose of 46 units. 22 months after discharge, the medical therapy consisted of metformin, liraglutide, and insulin glargine (26 units per day), antihypertensive medication was reduced to bisoprolol and valsartan. Blood pressure was well controlled, hemoglobin A1c was 6.6%. As a likely explanation, undocumented, asymptomatic hypoglycemic events with a post-hypoglycemic hormonal stimulation were the cause for the poor glycemic and blood-pressure control. A step-wise reduction of insulin translated into a better glycemic and blood-pressure control.Conclusions: Undocumented, asymptomatic hypoglycemic events and post-hypoglycemic hormonal stimulation were the likely cause for the poor glycemic and blood-pressure control prior to index hospitalization. A step-wise reduction of insulin concurrently translated into a better glycemic and blood-pressure control.

Opportunity of using dietary supplements, control of blood pressure as a complex treatment of arterial hypertension

2020 ◽  
pp. 20-27
Author(s):  
O. Gizinger
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Dietary Supplements ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Complex Treatment ◽  
Complex Product ◽  
And Control

The article presents the results of a research of evaluation of the effectiveness and safety of dietary supplements and control of blood pressure as a complex treatment in patients with the 1st and 2nd stages of arterial hypertension (AH). It was found that using the complex product blood pressure control stabilises systolic and diastolic blood pressure.

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