scholarly journals Evaluating the Performance of Ultra-Low-Field MRI for in-vivo 3D Current Density Imaging of the Human Head

2020 ◽  
Vol 8 ◽  
Author(s):  
Peter Hömmen ◽  
Antti J. Mäkinen ◽  
Alexander Hunold ◽  
René Machts ◽  
Jens Haueisen ◽  
...  
Keyword(s):  
Current Density ◽  
Human Head ◽  
Low Field ◽  
Current Density Imaging ◽  
Low Field Mri

Current-density imaging using ultra-low-field MRI with zero-field encoding

2014 ◽  
Vol 32 (6) ◽  
pp. 766-770 ◽  
Author(s):  
Panu T. Vesanen ◽  
Jaakko O. Nieminen ◽  
Koos C.J. Zevenhoven ◽  
Yi-Cheng Hsu ◽  
Risto J. Ilmoniemi
Keyword(s):  
Current Density ◽  
Zero Field ◽  
Low Field ◽  
Current Density Imaging ◽  
Low Field Mri

scholarly journals Demonstration of full tensor current density imaging using ultra-low field MRI

2019 ◽  
Vol 60 ◽  
pp. 137-144 ◽  
Author(s):  
P. Hömmen ◽  
J.-H. Storm ◽  
N. Höfner ◽  
R. Körber
Keyword(s):  
Current Density ◽  
Low Field ◽  
Current Density Imaging ◽  
Low Field Mri ◽  
Tensor Current

Current-density imaging using ultra-low-field MRI with adiabatic pulses

2014 ◽  
Vol 32 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Jaakko O. Nieminen ◽  
Koos C.J. Zevenhoven ◽  
Panu T. Vesanen ◽  
Yi-Cheng Hsu ◽  
Risto J. Ilmoniemi
Keyword(s):  
Current Density ◽  
Adiabatic Pulses ◽  
Low Field ◽  
Current Density Imaging ◽  
Low Field Mri

Sequences for current-density and conductivity imaging with ultra-low-field MRI

2012 ◽  
Vol 57 (SI-1 Track-M) ◽  
Author(s):  
J. O. Nieminen ◽  
P. T. Vesanen ◽  
R. J. Ilmoniemi
Keyword(s):  
Current Density ◽  
Low Field ◽  
Low Field Mri ◽  
Conductivity Imaging

scholarly journals Sensitivity and resolution improvement for in-vivo magnetic resonance current density imaging (MRCDI) of the human brain

2021 ◽  
Author(s):  
Cihan Goksu ◽  
Klaus Scheffler ◽  
Frodi Gregersen ◽  
Hasan H Eroglu ◽  
Rahel Heule ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Current Density ◽  
Current Flow ◽  
Transcranial Electrical Stimulation ◽  
Physiological Noise ◽  
Flow Simulations ◽  
Current Density Imaging ◽  
Resonance Current

Purpose: Magnetic resonance current density imaging (MRCDI) combines MR brain imaging with the injection of time-varying weak currents (1-2 mA) to assess the current flow pattern in the brain. However, the utility of MRCDI is still hampered by low measurement sensitivity and poor image quality. Methods: We recently introduced a multi-gradient-echo-based MRCDI approach that has the hitherto best documented efficiency. We now advanced our MRCDI approach in three directions and performed phantom and in-vivo human brain experiments for validation: First, we verified the importance of enhanced spoiling and optimize it for imaging of the human brain. Second, we improved the sensitivity and spatial resolution by using acquisition weighting. Third, we added navigators as a quality control measure for tracking physiological noise. Combining these advancements, we tested our optimized MRCDI method by using 1 mA transcranial electrical stimulation (TES) currents injected via two different electrode montages in five subjects. Results: For a session duration of 4:20 min, the new MRCDI method was able to detect magnetic field changes caused by the TES current flow at a sensitivity level of 84 pT, representing in a twofold increase relative to our original method. Comparing both methods to current flow simulations based on personalized head models demonstrated a consistent increase in the coefficient of determination of ∆R2=0.12 for the current-induced magnetic fields and ∆R2=0.22 for the current flow reconstructions. Interestingly, some of the simulations still clearly deviated from the measurements despite of the strongly improved measurement quality. This suggests that MRCDI can reveal useful information for the improvement of head models used for current flow simulations. Conclusion: The advanced method strongly improves the sensitivity and robustness of MRCDI and is an important step from proof-of-concept studies towards a broader application of MRCDI in clinical and basic neuroscience research.

scholarly journals Human in-vivo brain magnetic resonance current density imaging (MRCDI)

NeuroImage ◽  
2018 ◽  
Vol 171 ◽  
pp. 26-39 ◽  
Author(s):  
Cihan Göksu ◽  
Lars G. Hanson ◽  
Hartwig R. Siebner ◽  
Philipp Ehses ◽  
Klaus Scheffler ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Current Density ◽  
Current Density Imaging ◽  
Resonance Current

scholarly journals [OA019] Human in-vivo Magnetic Resonance Current Density Imaging (MRCDI) and MR Electrical Impedance Tomography (MREIT)

2018 ◽  
Vol 52 ◽  
pp. 8
Author(s):  
Cihan Göksu ◽  
Lars G. Hanson ◽  
Hartwig R. Siebner ◽  
Philipp Ehses ◽  
Klaus Scheffler ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Electrical Impedance Tomography ◽  
Current Density ◽  
Electrical Impedance ◽  
Impedance Tomography ◽  
Current Density Imaging ◽  
Resonance Current
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