scholarly journals Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation

2020 ◽  
Vol 11 ◽  
Author(s):  
Rouba Kozak ◽  
Tamás Kiss ◽  
Keith Dlugolenski ◽  
David E. Johnson ◽  
Roxanne R. Gorczyca ◽  
...  
Author(s):  
G. C. Smith ◽  
R. L. Heberling ◽  
S. S. Kalter

A number of viral agents are recognized as and suspected of causing the clinical condition “gastroenteritis.” In our attempts to establish an animal model for studies of this entity, we have been examining the nonhuman primate to ascertain what viruses may be found in the intestinal tract of “normal” animals as well as animals with diarrhea. Several virus types including coronavirus, adenovirus, herpesvirus, and picornavirus (Table I) were detected in our colony; however, rotavirus, astrovirus, and calicivirus have not yet been observed. Fecal specimens were prepared for electron microscopy by procedures reported previously.


2001 ◽  
Vol 11 ◽  
pp. S282-S283
Author(s):  
D. Marazziti ◽  
I. Masala ◽  
G. Giannaccini ◽  
E. Di Nasso ◽  
L. Betti ◽  
...  

2011 ◽  
Vol 52 (10) ◽  
pp. 7365 ◽  
Author(s):  
J. Crawford Downs ◽  
Claude F. Burgoyne ◽  
William P. Seigfreid ◽  
Juan F. Reynaud ◽  
Nicholas G. Strouthidis ◽  
...  

2006 ◽  
Vol 97 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Line Mogensen ◽  
Carl Christian Kinze ◽  
Thomas Werge ◽  
Henrik Berg Rasmussen

Nature ◽  
1990 ◽  
Vol 347 (6289) ◽  
pp. 146-151 ◽  
Author(s):  
Pierre Sokoloff ◽  
Bruno Giros ◽  
Marie-Pascale Martres ◽  
Marie-Louise Bouthenet ◽  
Jean-Charles Schwartz

2006 ◽  
Vol 21 (11) ◽  
pp. 1879-1891 ◽  
Author(s):  
Naomi P. Visanji ◽  
Jordi Gomez-Ramirez ◽  
Tom H. Johnston ◽  
Donna Pires ◽  
Valerie Voon ◽  
...  

1989 ◽  
Vol 170 (5) ◽  
pp. 1551-1558 ◽  
Author(s):  
J C Brouet ◽  
K Dellagi ◽  
M C Gendron ◽  
A Chevalier ◽  
C Schmitt ◽  
...  

Most studies using rabbit or mouse antisera failed to detect CRI between human IgM directed to MAG. We show here that 9 of 10 such IgM express a public CRI as defined by a nonhuman primate antiserum. Shared idiotype is likely involved in (or close to) the combining site of those IgM since antiidiotypic serum inhibited the binding of IgM to MAG and reacted with IgM having different variable regions of light and heavy chains. Partial aminoterminal sequence of heavy and light chains showed that anti-MAG IgM use either lambda chains (one IgM) or kappa light chains (six IgM) of different variability subgroups (V kappa IV in three instances, V kappa I in two, and V kappa II in one), whereas heavy chains belong to the VHIII (six IgM) or to the VHII (1 IgM) subgroup. These features distinguish these IgM from other human monoclonal IgM with a defined antibody activity, such as rheumatoid factors or cold agglutinins.


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