scholarly journals No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation

2020 ◽  
Vol 10 ◽  
Author(s):  
Rong Hu ◽  
Daniel T. Barratt ◽  
Janet K. Coller ◽  
Benedetta C. Sallustio ◽  
Andrew A. Somogyi
Keyword(s):  
Major Effect ◽  
Innate Immune ◽  
Post Transplantation ◽  
Kidney Rejection ◽  
Acute Kidney Rejection

DISCOVERY AND VALIDATION OF PERIPHERAL BLOOD DIAGNOSTIC BIOMARKERS FOR ACUTE KIDNEY REJECTION: REPORT OF THE TGCG STUDY.

2010 ◽  
Vol 90 ◽  
pp. 242
Author(s):  
S. Kurian ◽  
A. Williams ◽  
D. Campbell ◽  
T. Mondala ◽  
S. Head ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Diagnostic Biomarkers ◽  
Kidney Rejection ◽  
Acute Kidney Rejection

scholarly journals A new lateral flow assay to detect sIL-2R during T-cell mediated rejection after kidney transplantation

The Analyst ◽  
2021 ◽  
Author(s):  
Lisa K. Seiler ◽  
Rebecca Jonczyk ◽  
Patrick Lindner ◽  
Ncog Linh Phung ◽  
Christine S. Falk ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
T Cell ◽  
Point Of Care ◽  
High Specificity ◽  
Lateral Flow ◽  
Lateral Flow Assay ◽  
Point Of Care Test ◽  
Specificity And Sensitivity ◽  
Kidney Rejection ◽  
Acute Kidney Rejection

In this work a novel point of care test to detect sIL-2R during acute kidney rejection with high specificity and sensitivity was developed.

Molecular Signature in the Peripheral Blood for Sub-Clinical Acute Kidney Rejection.

2014 ◽  
Vol 98 ◽  
pp. 228
Author(s):  
J. Friedewald ◽  
S. Kurian ◽  
J. Levitsky ◽  
S. Brietigam ◽  
J. Charette ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Molecular Signature ◽  
Kidney Rejection ◽  
Acute Kidney Rejection

HILDA/LIF URINARY EXCRETION DURING ACUTE KIDNEY REJECTION

1992 ◽  
Vol 53 (3) ◽  
pp. 655-658 ◽  
Author(s):  
JEAN LUC TAUPIN ◽  
DELPHINE MOREL ◽  
JEAN FRANÇCCOIS MOREAU ◽  
NORBERT GUALDE ◽  
LUC POTAUX ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Kidney Rejection ◽  
Acute Kidney Rejection

scholarly journals Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation

2009 ◽  
Vol 90 (11) ◽  
pp. 2686-2694 ◽  
Author(s):  
Thomas Kuri ◽  
Xiaonan Zhang ◽  
Matthias Habjan ◽  
Luis Martínez-Sobrido ◽  
Adolfo García-Sastre ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Major Effect ◽  
Plasmacytoid Dendritic Cells ◽  
Effector Proteins ◽  
Innate Immune ◽  
Type I Interferons ◽  
Individual Treatment ◽  
Type I ◽  
Sars Coronavirus ◽  
Cytokines And Chemokines

SARS coronavirus (SARS-CoV) is known to efficiently suppress the induction of antiviral type I interferons (IFN-α/β) in non-lymphatic cells through inhibition of the transcription factor IRF-3. Plasmacytoid dendritic cells, in contrast, respond to infection with production of high levels of IFNs. Here, we show that pretreatment of non-lymphatic cells with small amounts of IFN-α (IFN priming) partially overturns the block in IFN induction imposed by SARS-CoV. IFN priming combined with SARS-CoV infection substantially induced genes for IFN induction, IFN signalling, antiviral effector proteins, ubiquitination and ISGylation, antigen presentation and other cytokines and chemokines, whereas each individual treatment had no major effect. Curiously, however, despite this typical IFN response, neither IRF-3 nor IRF-7 was transported to the nucleus as a sign of activation. Taken together, our results suggest that (i) IFN, as it is produced by plasmacytoid dendritic cells, could enable tissue cells to launch a host response to SARS-CoV, (ii) IRF-3 and IRF-7 may be active at subdetectable levels, and (iii) SARS-CoV does not activate IRF-7.

scholarly journals Daclizumab as escape therapy for late acute kidney rejection in the presence of FK506 nephrotoxicity

2000 ◽  
Vol 13 (2) ◽  
pp. 169-171 ◽  
Author(s):  
José Oberholzer ◽  
Frédéric Triponez ◽  
Pierre Yves Martin ◽  
Carole Williamson ◽  
Philippe Morel
Keyword(s):  
Kidney Rejection ◽  
Acute Kidney Rejection
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