scholarly journals The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling

2019 ◽  
Vol 10 ◽  
Author(s):  
Xiaoxue Gong ◽  
Hui Hu ◽  
Yi Qiao ◽  
Pengfei Xu ◽  
Mengqi Yang ◽  
...  
Keyword(s):  
Insulin Signaling ◽  
Renin Angiotensin System ◽  
Behavioral Changes ◽  
Angiotensin System ◽  
Renin Angiotensin

scholarly journals Blockade of the Renin‐Angiotensin System Suggests p38 as a Cross‐Talk Mechanism Between the Renin‐Angiotensin System and the Insulin Signaling Pathway

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Megan Danielle Schertzer ◽  
Timothy Ryan Erdei ◽  
Sarah Elaine Conway ◽  
Taylor Michelle Ziga ◽  
Sherry Oden Kasper ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Cross Talk ◽  
Insulin Signaling ◽  
Renin Angiotensin System ◽  
Insulin Signaling Pathway ◽  
Angiotensin System ◽  
Renin Angiotensin

Physiological and behavioral changes induced by over-expressed renin–angiotensin system in rats

2007 ◽  
Author(s):  
Michal Zeman ◽  
Lucia Kršková ◽  
Katarína Stebelová ◽  
Michaela Vrabcová ◽  
Iveta Herichová
Keyword(s):  
Renin Angiotensin System ◽  
Behavioral Changes ◽  
Angiotensin System ◽  
Renin Angiotensin

scholarly journals Involvement of NF‐kappaB in the Cross Talk Between the Renin‐Angiotensin System and Insulin Signaling in Skeletal Muscle in Burn Injury

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Michelle Marie Wayne ◽  
Jacob Lepard ◽  
Jeshurun Benavides ◽  
Lori Gail West ◽  
Blaine Enderson ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cross Talk ◽  
Insulin Signaling ◽  
Burn Injury ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
The Cross ◽  
Nf Kappab

scholarly journals High, but not low, exercise volume shifts the balance of renin-angiotensin system toward ACE2/Mas receptor axis in skeletal muscle in obese rats

2017 ◽  
Vol 313 (4) ◽  
pp. E473-E482 ◽  
Author(s):  
Eliete Dalla Corte Frantz ◽  
Isabele Gomes Giori ◽  
Marcus Vinícius Machado ◽  
D’Angelo Carlo Magliano ◽  
Fernanda Marques Freitas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Skeletal Muscle ◽  
Body Mass ◽  
Insulin Signaling ◽  
Renin Angiotensin System ◽  
The Body ◽  
Receptor Expression ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Mas Receptor

Metabolic syndrome is a cluster of metabolic risk factors that is linked to central obesity, elevated blood pressure, insulin resistance (IR), and dyslipidemia, where the renin-angiotensin system (RAS) may provide a link among them. This study aimed to evaluate volume exercise effects comparing low vs. high volume of chronic aerobic exercise on RAS axes in skeletal muscle in a diet-induced obesity (DIO) rat model. For this, male Wistar-Kyoto rats were fed a standard chow (SC) diet or a high-fat (HF) diet for 32 wk. Animals receiving the HF diet were randomly divided into low exercise volume (LEV, 150 min/wk) and high exercise volume (HEV, 300 min/wk) at the 20th week. After 12 wk of aerobic treadmill training, the body mass and composition, blood pressure, glucose and lipid metabolism, RAS axes, insulin signaling, and inflammatory pathway were performed. HEV slowed the body mass gain, reduced intra-abdominal fat pad and leptin levels, improved total and peripheral body composition and inflammatory cytokine, reduced angiotensin II type 1 receptor expression, and increased Mas receptor protein expression compared with the HF animals. Sedentary groups (SC and HF) presented lower time to exhaustion and maximal velocity compared with the LEV and HEV groups. Both exercise training groups showed reduced resting systolic blood pressure and heart rate, improved glucose tolerance, IR, insulin signaling, and lipid profile. We conclude that the HEV, but not LEV, shifted the balance of RAS toward the ACE2/Mas receptor axis in skeletal muscle, presenting protective effects against the DIO model.

Role of genetic variability in the renin-angiotensin system in diabetic and nondiabetic renal disease

2001 ◽  
Vol 21 (6) ◽  
pp. 580-592 ◽  
Author(s):  
Arnold Boonstra ◽  
Dick de Zeeuw ◽  
Paul E. de Jong ◽  
Gerjan Navis
Keyword(s):  
Genetic Variability ◽  
Renal Disease ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin
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