scholarly journals Simultaneous Extraction and Determination of Compounds With Different Polarities From Platycladi Cacumen by AQ C18-Based Vortex-Homogenized Matrix Solid-Phase Dispersion With Ionic Liquid

2019 ◽  
Vol 9 ◽  
Author(s):  
Mingya Ding ◽  
Jin Li ◽  
Shuhan Zou ◽  
Ge Tang ◽  
Xiumei Gao ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Solid Phase ◽  
Simultaneous Extraction ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion

scholarly journals New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1312
Author(s):  
Luyi Jiang ◽  
Jie Wang ◽  
Huan Zhang ◽  
Caijing Liu ◽  
Yiping Tang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
High Performance ◽  
Solid Phase ◽  
Hplc Method ◽  
Factors Affecting ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Quantitative Determination Method ◽  
Grinding Time

In this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C18 and silica gel were investigated. The strategy included two steps: Extraction and determination. Wasted crab shells were used as an alternative adsorbent and ionic liquid was used as an alternative solvent in the first step. Factors affecting extraction efficiency were optimized: A sample/adsorbent ratio of 2:1, a grinding time of 3 min, a vortex time of 3 min, and ionic liquid ([Domim]HSO4, 250 mM) was used as eluent in the VS-MSPD procedure. As a result, the established method provided satisfactory linearity (R > 0.999), good accuracy and high reproducibility (RSD < 4.60%), and it exhibited the advantages of smaller sample amounts, shorter extraction time, less volume of elution solvent, and was much more environmental-friendly when compared with other conventional methods.

scholarly journals A Beta/ZSM-22 Zeolites-Based-Mixed Matrix Solid-Phase Dispersion Method for the Simultaneous Extraction and Determination of Eight Compounds with Different Polarities in Viticis Fructus by High-Performance Liquid Chromatography

Molecules ◽  
2019 ◽  
Vol 24 (19) ◽  
pp. 3423 ◽  
Author(s):  
He ◽  
Li ◽  
Pang ◽  
Wang ◽  
Jin ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
High Performance ◽  
Solid Phase ◽  
Mass Ratio ◽  
Mixed Matrix ◽  
Dispersion Method ◽  
Simultaneous Extraction ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion

Viticis Fructus (VF) was named Manjingzi as a commonly used traditional Chinese medicine (TCM) targeting various pains and inflammation for more than 2000 years. To guarantee the quality of Viticis Fructus, a simple, quick and eco-friendly Beta/ZSM-22 zeolites-based-mixed matrix solid-phase dispersion method (B/Z-MMSPD) was established for simultaneous extraction and determination of eight compounds (two phenolic acids, two iridoid glycosides, vanillin and three flavonoids) with different polarities from Viticis Fructus by high performance liquid chromatography coupled with a diode array detector (HPLC-DAD). Beta and ZSM-22 were mixed as the sorbent. Water, tetrahydrofuran and methanol were blended with certain ratio as the eluent. Several parameters including types of sorbents, mass ratio of Beta to ZSM-22, mass ratio of matrix to sorbent, grinding time, types, concentration and volume of eluent were optimized. The recoveries of eight analytes were within the range of 95.0%–105% (RSDs ≤ 4.13%). The limits of detection and limits of quantitation ranged from 0.5 to 5.5 μg/g and from 1.5 to 16 μg/g, respectively. Compared to the traditional extract methods, it was a simple, rapid, efficient and green method. The results demonstrated that a simple, rapid, efficient and green B/Z-MMSPD was developed for the simultaneous extraction and determination of eight target analytes with different polarities for quality control of Viticis Fructus.

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