scholarly journals Changes in Membrane Protein Clustering in Peripheral Lymphocytes in an Animal Model of Depression Parallel Those Observed in Naïve Depression Patients: Implications for the Development of Novel Biomarkers of Depression

2018 ◽  
Vol 9 ◽  
Author(s):  
Raquel Romay-Tallon ◽  
Erin Kulhawy ◽  
Kyle J. Brymer ◽  
Josh Allen ◽  
Tania Rivera-Baltanas ◽  
...  
Keyword(s):  
Animal Model ◽  
Membrane Protein ◽  
Protein Clustering ◽  
Peripheral Lymphocytes ◽  
Animal Model Of Depression ◽  
Novel Biomarkers ◽  
Membrane Protein Clustering

scholarly journals Stability Analysis of a Bulk–Surface Reaction Model for Membrane Protein Clustering

2020 ◽  
Vol 82 (2) ◽  
Author(s):  
Lucas M. Stolerman ◽  
Michael Getz ◽  
Stefan G. Llewellyn Smith ◽  
Michael Holst ◽  
Padmini Rangamani
Keyword(s):  
Stability Analysis ◽  
Membrane Protein ◽  
Surface Reaction ◽  
Reaction Model ◽  
Protein Clustering ◽  
Bulk Surface ◽  
Membrane Protein Clustering ◽  
Surface Reaction Model

scholarly journals Lipid Composition Modulates Membrane Protein Clustering

2016 ◽  
Vol 110 (3) ◽  
pp. 81a
Author(s):  
Anna L. Duncan ◽  
Heidi Koldsø ◽  
Tyler Reddy ◽  
Jean Helie ◽  
Mark S.P. Sansom
Keyword(s):  
Membrane Protein ◽  
Lipid Composition ◽  
Protein Clustering ◽  
Membrane Protein Clustering

scholarly journals The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Elisa Merklinger ◽  
Jan-Gero Schloetel ◽  
Pascal Weber ◽  
Helena Batoulis ◽  
Sarah Holz ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Protein ◽  
Protein Interactions ◽  
Cluster Size ◽  
Protein Domain ◽  
Self Organization ◽  
Cytoplasmic Protein ◽  
Transmembrane Segment ◽  
Protein Clustering ◽  
Membrane Protein Clustering

Molecule clustering is an important mechanism underlying cellular self-organization. In the cell membrane, a variety of fundamentally different mechanisms drive membrane protein clustering into nanometre-sized assemblies. To date, it is unknown whether this clustering process can be dissected into steps differentially regulated by independent mechanisms. Using clustered syntaxin molecules as an example, we study the influence of a cytoplasmic protein domain on the clustering behaviour. Analysing protein mobility, cluster size and accessibility to myc-epitopes we show that forces acting on the transmembrane segment produce loose clusters, while cytoplasmic protein interactions mediate a tightly packed state. We conclude that the data identify a hierarchy in membrane protein clustering likely being a paradigm for many cellular self-organization processes.

scholarly journals Mathematical Simulation of Membrane Protein Clustering for Efficient Signal Transduction

2012 ◽  
Vol 40 (11) ◽  
pp. 2307-2318 ◽  
Author(s):  
Krishnan Radhakrishnan ◽  
Ádám Halász ◽  
Meghan M. McCabe ◽  
Jeremy S. Edwards ◽  
Bridget S. Wilson
Keyword(s):  
Signal Transduction ◽  
Membrane Protein ◽  
Mathematical Simulation ◽  
Protein Clustering ◽  
Membrane Protein Clustering

Modulated red blood cell survival by membrane protein clustering

1995 ◽  
Vol 144 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Laura Chiarantini ◽  
Luigia Rossi ◽  
Alessandra Fraternale ◽  
Mauro Magnani
Keyword(s):  
Membrane Protein ◽  
Blood Cell ◽  
Cell Survival ◽  
Red Blood Cell ◽  
Protein Clustering ◽  
Membrane Protein Clustering
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