scholarly journals CuO and CeO2 Nanostructures Green Synthesized Using Olive Leaf Extract Inhibits the Growth of Highly Virulent Multidrug Resistant Bacteria

2018 ◽  
Vol 9 ◽  
Author(s):  
Qaisar Maqbool ◽  
Mudassar Nazar ◽  
Ayesha Maqbool ◽  
Muhammad T. Pervez ◽  
Nyla Jabeen ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Olive Leaf ◽  
Multidrug Resistant Bacteria ◽  
Olive Leaf Extract ◽  
Highly Virulent

scholarly journals Olive Leaf Extract Modulates Quorum Sensing Genes and Biofilm Formation in Multi-Drug Resistant Pseudomonas aeruginosa

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 526
Author(s):  
Nazly R. El-sayed ◽  
Reham Samir ◽  
Lina Jamil M. Abdel-Hafez ◽  
Mohammed A. Ramadan
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Green Tea ◽  
Biofilm Formation ◽  
Leaf Extract ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Olive Leaf ◽  
Leaf Extracts ◽  
Olive Leaf Extract

Biofilm acts as a complex barrier against antibiotics. In this study, we investigated the inhibitory activities of Olea europaea (olive) leaves Camellia sinensis (green tea), Styrax benzoin, Ocimum basilicum, Humulus lupulus, Ruta graveolens, and Propolis extracts on the biofilm formation, pyocyanin production, and twitching motility of Pseudomonas aeruginosa isolates. Moreover, we investigated the effect of olive leaf extract on the transcription of some biofilm related genes. A total of 204 isolates of Pseudomonas were collected from different Egyptian hospitals. A susceptibility test, carried out using the disc diffusion method, revealed that 49% of the isolates were multidrug-resistant. More than 90% of the isolates were biofilm-forming, of which 26% were strong biofilm producers. At subinhibitory concentrations, green tea and olive leaf extracts had the highest biofilm inhibitory effects with 84.8% and 82.2%, respectively. The expression levels of lasI, lasR, rhlI, and rhlR treated with these extracts were significantly reduced (p < 0.05) by around 97–99% compared to untreated isolates. This study suggests the ability of olive leaf extract to reduce the biofilm formation and virulence factor production of P. aeruginosa through the down regulation of quorum sensing (QS) genes. This may help in reducing our dependence on antibiotics and to handle biofilm-related infections of opportunistic pathogens more efficiently.

scholarly journals Retracted Article: Organometallic Ag nanostructures prepared using Hypericum perforatum extract are highly effective against multidrug-resistant bacteria

RSC Advances ◽  
2018 ◽  
Vol 8 (53) ◽  
pp. 30562-30572 ◽  
Author(s):  
Qaisar Maqbool ◽  
Dariusz Kruszka ◽  
Piotr Kachlicki ◽  
Gregory Franklin
Keyword(s):  
Hypericum Perforatum ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Antibacterial Performance ◽  
Highly Effective ◽  
Retracted Article ◽  
First Time ◽  
Highly Virulent

The tuning of bulk Ag+ ions into organometallic Ag nanostructures using Hypericum perforatum extract is reported for the first time. The green-synthesised nanostructures showed an auspicious antibacterial performance against highly virulent multidrug resistant bacteria.

C-terminal Lysine-Linked Magainin 2 with Increased Activity Against Multidrug-Resistant Bacteria

2016 ◽  
Vol 23 (8) ◽  
pp. 738-747 ◽  
Author(s):  
Esteban N. Lorenzón ◽  
Norival A. Santos-Filho ◽  
Matheus A. S. Ramos ◽  
Tais M. Bauab ◽  
Ilana L. B. C. Camargo ◽  
...  
Keyword(s):  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Increased Activity
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