scholarly journals Efficacy and Safety of Oral TDF-Based Pre-exposure Prophylaxis for Men Who Have Sex With Men: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 9 ◽  
Author(s):  
Xiaojie Huang ◽  
Jianhua Hou ◽  
Aixin Song ◽  
Xinchao Liu ◽  
Xiaodong Yang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Efficacy And Safety ◽  
Sex With Men ◽  
Exposure Prophylaxis

A Global Estimate of the Acceptability of Pre-exposure Prophylaxis for HIV Among Men Who have Sex with Men: A Systematic Review and Meta-analysis

2017 ◽  
Vol 22 (4) ◽  
pp. 1063-1074 ◽  
Author(s):  
Peng Peng ◽  
Shu Su ◽  
Christopher K. Fairley ◽  
Minjie Chu ◽  
Shengyang Jiang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Global Estimate ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals Awareness and Use of Post-exposure Prophylaxis for HIV Prevention Among Men Who Have Sex With Men: A Systematic Review and Meta-Analysis

2022 ◽  
Vol 8 ◽  
Author(s):  
Junyan Jin ◽  
Runsong Sun ◽  
Tingting Mu ◽  
Taiyi Jiang ◽  
Lili Dai ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hiv Prevention ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Structural Barriers ◽  
Post Exposure ◽  
At Risk Populations ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
Over Time

Background: The use of post-exposure prophylaxis (PEP) is effective in reducing HIV risk, but it is underused by men who have sex with men (MSM) due to certain psychological and sociostructural factors. This article assessed the awareness and use of PEP among MSM in an effort to increase the visibility and uptake of PEP among at-risk populations.Methods: We conducted a systematic literature search of the PubMed, Web of Science, PsycINFO, and Google Scholar electronic databases. Studies were screened for inclusion, and relevant data were abstracted, assessed for bias, and synthesized. Pooled effect estimates were calculated using random effects meta-analysis, meta-regression and subgroup analysis, and a qualitative review and risk of bias assessment were performed (PROSPERO, CRD42019123815).Results: Twenty eligible studies involving 12,579 MSM were included in the meta-analysis. The pooled estimate of the proportions of MSM who were aware of PEP was modest at 59.9% (95% CI: 50.5~68.7) and that of MSM who previously used PEP was very low at 4.9% (95% CI: 2.4~9.8). PEP awareness showed no clear change over time, while PEP use significantly changed over time. Multiple factors affected awareness, including educational attainment, race/ethnicity, levels of HIV stigma, access to condoms, and so on. Many factors could potentially impede or facilitate the use of PEP, such as income, lack of PEP information, and partnership.Conclusion: We observed that PEP is an underused HIV prevention strategy among MSM and that once MSM become aware of PEP, the majority are willing to use it if they are supported appropriately in terms of a range of individual, social, and structural barriers.Systematic Review Registration: http://www.cdr.york.ac.uk/prospero, PROSPERO [CRD42019123815].

Sign in / Sign up

Export Citation Format

Share Document