scholarly journals Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and Suppresses Tumor Growth on Xenografts Tumor Animal Model

2018 ◽  
Vol 8 ◽  
Author(s):  
Ye Cheng ◽  
Weidong He ◽  
Yongming He
Keyword(s):  
Animal Model ◽  
Tumor Growth ◽  
A549 Cell ◽  
Cell Apoptosis

Pleurotus nebrodensis polysaccharide(PN50G) evokes A549 cell apoptosis by the ROS/AMPK/PI3K/AKT/mTOR pathway to suppress tumor growth

2016 ◽  
Vol 7 (3) ◽  
pp. 1616-1627 ◽  
Author(s):  
Haiyan Cui ◽  
Shufen Wu ◽  
Yunfei Shang ◽  
Zhenjing Li ◽  
Mianhua Chen ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Tumor Growth ◽  
A549 Cell ◽  
Cell Apoptosis ◽  
Mtor Pathway ◽  
Signal Transduction Pathways ◽  
Pleurotus Nebrodensis

The model for PN50G mediated signal transduction pathways in the regulation of tumor apoptosis in A549-bearing mice is proposed.

scholarly journals Retraction: FOXC1 silencing promotes A549 cell apoptosis through inhibiting the PI3K/AKT/hedgehog/Gli2 signaling pathway

RSC Advances ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 4572-4572
Author(s):  
Laura Fisher
Keyword(s):  
Signaling Pathway ◽  
A549 Cell ◽  
Cell Apoptosis

Retraction of ‘FOXC1 silencing promotes A549 cell apoptosis through inhibiting the PI3K/AKT/hedgehog/Gli2 signaling pathway’ by Pei Wang et al., RSC Adv., 2018, 8, 33786–33793, DOI: 10.1039/C8RA06041J.

scholarly journals Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist

Oncogene ◽  
2006 ◽  
Vol 25 (52) ◽  
pp. 6968-6974 ◽  
Author(s):  
H Yan ◽  
J Thomas ◽  
T Liu ◽  
D Raj ◽  
N London ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Melanoma Cell ◽  
Cell Apoptosis ◽  
A Cell ◽  
Inhibition Of Tumor Growth

scholarly journals Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis

2019 ◽  
Vol 144 (9) ◽  
pp. 2290-2302 ◽  
Author(s):  
Lenneke A.M. Cornelissen ◽  
Athanasios Blanas ◽  
Joost C. van der Horst ◽  
Laura Kruijssen ◽  
Anouk Zaal ◽  
...  
Keyword(s):  
Sialic Acid ◽  
T Cell ◽  
Tumor Growth ◽  
Cell Apoptosis ◽  
Acid Metabolism ◽  
Cd8 T Cell ◽  
T Cell Apoptosis

scholarly journals Mir-204 Regulates LPS-Induced A549 Cell Damage by Targeting FOXK2

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Shufen Li ◽  
Lifen Zhao ◽  
Xujiong Li ◽  
Gaiping Shang ◽  
Lijing Gao ◽  
...  
Keyword(s):  
A549 Cell ◽  
Cell Apoptosis ◽  
Cell Injury ◽  
Cell Damage ◽  
A549 Cells ◽  
Inflammatory Factors ◽  
Luciferase Reporter ◽  
Luciferase Reporter Gene ◽  
Downstream Target ◽  
Apoptosis Related Protein

Objective. To assess whether miR-204 and HA affect A549 cell injury induced by lipopolysaccharide. Material and Methods. A549 cells were treated with hirsutanol A, and cell damage was induced by LPS followed by analysis of cell proliferation by CCK-8, cell apoptosis by flow cytometry, apoptosis-related protein expression by western blot, downstream target of miR-20 by dual-luciferase reporter gene, and inflammatory factors by ELISA and PCR. Results. LPS can significantly inhibit the viability of A549 cells, induce cell apoptosis, and promote the release of IL-6, IL-1β, and TNF-α, while HA pretreatment can target FOXK2 by upregulating miR-204 levels, thereby alleviating apoptosis and promoting cell viability and at the same time inhibiting the release of inflammatory factors by inhibiting the activation of NF-κB. Conclusions. miR-204 participates in the protection of HA acute lung injury by targeting FOXK2.

scholarly journals Naloxone Counteracts the Promoting Tumor Growth Effects Induced by Morphine in an Animal Model of Triple-negative Breast Cancer

In Vivo ◽  
2019 ◽  
Vol 33 (3) ◽  
pp. 821-825 ◽  
Author(s):  
SABRINA BIMONTE ◽  
ANTONIO BARBIERI ◽  
MARCO CASCELLA ◽  
DOMENICA REA ◽  
GIUSEPPE PALMA ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Animal Model ◽  
Tumor Growth ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Growth Effects
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