scholarly journals Outcome of Patients With Esophageal Atresia and Very Low Birth Weight (≤ 1,500 g)

2020 ◽  
Vol 8 ◽  
Author(s):  
Laura Antonia Ritz ◽  
Anke Widenmann-Grolig ◽  
Stefan Jechalke ◽  
Sandra Bergmann ◽  
Dietrich von Schweinitz ◽  
...  
2017 ◽  
Vol 52 (10) ◽  
pp. 1567-1570 ◽  
Author(s):  
Andreas Schmidt ◽  
Florian Obermayr ◽  
Justus Lieber ◽  
Christian Gille ◽  
Frank Fideler ◽  
...  

2020 ◽  
Vol 10 (3) ◽  
pp. 315-326
Author(s):  
Rustam F. Mukhametshin ◽  
Nikita V. Toropov ◽  
Olga T. Kabdrakhmanova

This literature review is devoted to the problem of predicting in-hospital mortality in newborns with esophageal atresia (EA). According to epidemiological study data, in developed countries, the mortality rate in newborns with EA ranges from 9% to 11% over the past 20 years. Three classifications were developed, Waterston 1962, Montreal 1993, and Spitz 1994, to assess the prognostic significance of risk factors. They considered birth weight, the presence of concomitant congenital malformations and pneumonia, and the need for mechanical ventilation. The choice of a model for predicting outcomes depends on the level of health care and other factors, such as prematurity, low birth weight, late diagnosis, and infectious complications. These factors have a greater impact on patient survival in developing countries than in developed ones, where insurmountable risk factors come out on top: combined congenital malformations and very low birth weight. Also, the magnitude of diastasis between segments of the esophagus creates difficulties in choosing surgical tactics and managing such patients in the postoperative period. In addition, the management of such patients in the intensive care unit, both preoperatively and postoperatively, has a significant impact on the outcome. The literature review underlined "pain points" in the treatment of newborns with EA in regions with different levels of medical care, the consideration of which will allow the achievement of better results.


2009 ◽  
Vol 44 (12) ◽  
pp. 2278-2281 ◽  
Author(s):  
Mikael Petrosyan ◽  
Joaquin Estrada ◽  
Catherine Hunter ◽  
Russell Woo ◽  
James Stein ◽  
...  

Author(s):  
Mustafa O. Oztan ◽  
Tutku Soyer ◽  
Can I. Oztorun ◽  
Binali Firinci ◽  
Çiğdem U. Durakbaşa ◽  
...  

Abstract Introduction The data of the Turkish Esophageal Atresia Registry (TEAR) was evaluated to define the outcome of very low birth weight (VLBW) and low BW (LWB) infants with esophageal atresia (EA). Materials and Methods The data registered by 24 centers between 2014 and 2018 were evaluated for demographic features, prenatal findings, associated anomalies, surgical treatment, and outcome. Patients were enrolled in three groups according to their BWs (VLBW <1,500 g), LWB = 1,500–2,500 g), and normal BW (NBW; >2,500 g). Results Among the 389 cases, there were 37 patients (9.5%) in the VLBW group, 165 patients (42.4%) in the LBW group, and 187 patients (48.1%) in the NBW group. Prenatal diagnosis rates were similar among the three groups (29.7, 34.5, and 24.6%, respectively). The standard primary anastomosis was achieved at a significantly higher rate in NWB cases than in the other groups (p < 0.05). In patients with tracheoesophageal fistula (TEF), patients of the NBW group had significantly higher rates of full oral feedings, when compared with VLBW and LBW cases (p < 0.05). At the end of the first year, when we evaluate all patients, the number of cases with fistula recanalization and esophageal anastomotic strictures (AS) requiring esophageal dilatation was similar among the groups. The weight and height measurements at 6 months and 1 year of age of the survivors were similar in all the groups. The overall mortality rate was significantly higher in the VLBW and LBW groups, when compared with the NBW patients, even in patients with tension-free anastomosis (p < 0.05). The incidence of the associated anomalies was 90.6% in cases with mortality, which was significantly higher than in survivors (59.6%; p < 0.05). According to Spitz's classification, the survival rate was 87.1% in class I, 55.3% in class II, and 16.7% in class III. The most common causes of mortality were associated with cardiovascular diseases, pneumonia, and sepsis. Conclusion The national data of TEAR demonstrates that the developmental and feeding parameters are better in NBW patients. Although VLBW patients have higher risk of developing fistula canalization than the LBW and NBW groups, long-term complications, such as anastomotic strictures, weight, and height values, after 1 year are similar in both groups. According to our results, associated anomalies and LBWs are still significant risk factors for mortality in cases with EA.


2000 ◽  
Vol 9 (2) ◽  
pp. 73-78 ◽  
Author(s):  
A. Alfred Chahine ◽  
Richard R. Ricketts

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