scholarly journals Clinical Features of Acute Rhabdomyolysis in 55 Pediatric Patients

2020 ◽  
Vol 8 ◽  
Author(s):  
Zhengxiong Yao ◽  
Ping Yuan ◽  
Siqi Hong ◽  
Mei Li ◽  
Li Jiang
2019 ◽  
Author(s):  
Nadezhda Makazan ◽  
Elizaveta Orlova ◽  
Maria Kareva ◽  
Anna Kolodkina ◽  
Natalia Kalinchenko ◽  
...  

Author(s):  
Tatiana C R Senna ◽  
Maria Inês F Pimentel ◽  
Liliane F A Oliveira ◽  
Marcelo R Lyra ◽  
Mauricio N Saheki ◽  
...  

Abstract Background American tegumentary leishmaniasis (ATL) is a neglected disease with wide territorial distribution. Knowledge is scarce in children and adolescents. This study aims to compare the clinical features and response to antimony treatment in pediatric and adult patients with cutaneous leishmaniasis. Methods A retrospective cohort study was performed with 659 patients who attended a reference centre in Rio de Janeiro, Brazil, from 2000 to 2015. The pediatric cohort consisted of 131 (20%) patients and the adult cohort consisted of 528 (80%) patients. Results The epidemiological profile, antimony therapeutic response and incidence of adverse events (AE) were different in the pediatric cohort compared with the adult cohort. Mucosal form was less frequent in the pediatric cohort (RR:0.49, p=0.011). Lesions in the head, neck and trunk were more frequent in the pediatric cohort (RR:1.49, p=0.043). The effectiveness of antimony treatment was superior in the pediatric cohort (88.3% vs 76.6%) with a shorter healing time (RR:0.49, p=0.009). Pediatric patients had lower proportions of moderate to severe AE compared with adults (RR:0.45, p=0.027). Clinical AE predominated in the adult cohort (RR:0.40, p=0.000) and laboratory AE in the pediatric cohort (RR:1.50, p=0.023). Conclusions This study adds to the body of knowledge on differences that exist between different age groups in ATL.


2018 ◽  
Vol 11 (1) ◽  
pp. 028-034 ◽  
Author(s):  
Stephanie M. Young ◽  
Yan Tong Koh ◽  
Errol W. Chan ◽  
Shantha Amrith

The aim of this study was to evaluate the incidence, clinical features, and risk factors of sustaining inferior rectus (IR) palsy in a group of pediatric patients with orbital floor blowout fractures. We performed a retrospective case review of sequential cases of pediatric orbital floor blowout fractures (<18 years old) from 2000 to 2013 in a tertiary ophthalmic center in Singapore. A total of 48 patients were included in our study, of whom 5 had IR palsy (10.4%). Patients with IR palsy had a higher mean age (16.4 ± 1.5 years) compared with patients without IR palsy (12.4 ± 3.3 years), had significantly ( p < 0.05) worse preoperative motility, and had significantly greater proportion developing postoperative hypertropia (100%) compared with patients without IR palsy (4.7%). Our series of pediatric blowout fractures demonstrated IR palsy prevalence and clinical features for IR palsy which may be distinct to the pediatric group.


2020 ◽  
Vol 09 (02) ◽  
pp. 139-140 ◽  
Author(s):  
Nagehan Aslan ◽  
Dincer Yildizdas ◽  
Behruz Huseyınlı ◽  
Ozden Ozgur Horoz ◽  
Gulen Gul Mert ◽  
...  

AbstractEtiology of rhabdomyolysis includes hereditary muscle enzyme deficiencies, trauma, viral infections, excessive exercise, hypothyroidism, and medications such as colchicine, lithium, and statins. Several studies have reported that various antiepileptic drugs may induce rhabdomyolysis. Levetiracetam is one of the antiepileptic drugs implicated in the etiology of rhabdomyolysis. Herein, we present a case of rhabdomyolysis in an adolescent treated with levetiracetam. We wanted to draw attention to the increasing trend of levetiracetam-associated rhabdomyolysis frequency in pediatric patients.


2014 ◽  
Vol 55 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Chi-Yu Liu ◽  
Jiaan-Der Wang ◽  
Jen-Ta Yu ◽  
Li-Ching Wang ◽  
Ming-Chih Lin ◽  
...  

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