scholarly journals Risk Factors of Coronary Artery Abnormality in Children With Kawasaki Disease: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 7 ◽  
Author(s):  
Fan Yan ◽  
Bo Pan ◽  
Huichao Sun ◽  
Jie Tian ◽  
Mi Li
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Coronary Artery ◽  
Kawasaki Disease ◽  
Meta Analysis ◽  
Coronary Artery Abnormality

scholarly journals Risk factors of premature coronary artery disease in Iran: A systematic review and meta‐analysis

2019 ◽  
Vol 49 (7) ◽  
Author(s):  
Hoorak Poorzand ◽  
Konstantinos Tsarouhas ◽  
Seyyed Amin Hozhabrossadati ◽  
Nastaran Khorrampazhouh ◽  
Yones Bondarsahebi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Meta Analysis ◽  
Premature Coronary Artery Disease ◽  
Artery Disease

scholarly journals Hypertension and coronary artery ectasia: a systematic review and meta-analysis study

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mostafa Bahremand ◽  
Ehsan Zereshki ◽  
Behzad Karami Matin ◽  
Mansour Rezaei ◽  
Hamidreza Omrani
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Coronary Artery ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Random Effects Model ◽  
Index Subgroup ◽  
Coronary Artery Ectasia ◽  
Analysis Study ◽  
Multiple Risk Factors

Abstract Background Coronary artery ectasia (CAE) is characterized by the enlargement of a coronary artery to 1.5 times or more than other non-ectasia parts of the vessel. It is important to investigate the association of different factors and CAE because there are controversial results between available studies. We perform this systematic review and meta-analysis to evaluate the effects of hypertension (HTN) on CAE. Methods To find the potentially relevant records, the electronic databases, including Scopus, PubMed, and Science Direct were searched on 25 July 2019 by two of the authors independently. In the present study, the pooled odds ratio (OR) accompanied by 95 % confidence intervals (CIs) were calculated by a random-effects model. Heterogeneity presented with the I2 index. Subgroup analysis and sensitivity analysis by the Jackknife approach was performed. Results Forty studies with 3,263 cases and 7,784 controls that investigated the association between HTN and CAE were included. The pooled unadjusted OR of CAE in subjects with HTN in comparison by subjects without HTN was estimated 1.44 (95 % CI, 1.24 to 1.68) with moderate heterogeneity (I2 = 41 %, Cochran’s Q P = 0.004). There was no evidence of publication bias in the analysis of HTN and CAE with Egger’s test (P = 0.171), Begg’s test (P = 0.179). Nine articles reported the adjusted effect of HTN on CAE by 624 cases and 628 controls. The findings indicated the overall adjusted OR was 1.03 (95 % CI, 0.80 to 1.25) with high heterogeneity (I2 = 58.5 %, Cochran’s Q P = 0.013). Conclusions We found that when the vessel was in normal condition, HTN was not very effective in increasing the chance of CAE and only increased the CAE chance by 3 %. This is an important issue and a warning to people who have multiple risk factors together. More studies need to be performed to further establish these associations by reported adjusted effects.

Opioid dependency and myocardial infarction: A systematic review and meta-analysis.

2021 ◽  
Vol 16 ◽  
Author(s):  
Farahnaz Rohani ◽  
Arash Akhavan Rezayat ◽  
Ahmadreza Zarifian ◽  
Mohammad Ghasemi Nour ◽  
Farveh Vakilian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Systematic Review ◽  
Coronary Artery Disease ◽  
Developing Countries ◽  
Coronary Artery ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Health Concern ◽  
Artery Disease

Background: Coronary artery disease is a major cause of morbidity and mortality worldwide. A major health concern in developing countries is opioid addiction, which has controversial cardiovascular side effects. We aimed to investigate whether myocardial infarction (MI) and its risk factors are associated with morphine dependency in the Iranian population. Methods: Electronic databases, including PubMed, Medline, Scopus, SID, Elmnet, and Magiran were searched to find published articles including the keywords morphine, coronary artery disease, hypertension, hyperlipidemia, and diabetes mellitus. Results: Twelve studies involving 25,800 people were included in the systematic review and meta-analysis. Morphine dependency was significantly associated with MI with an adjusted odds ratio (AOR) of 2.28 (95%CI=1.26-4.11). It didn’t have significant associations with hypertension (AOR=0.952; 95%CI=0.696-1.301) nor diabetes (AOR=0.895; 95%CI=0.644-1.246). Morphine dependency also had no significant association with hyperlipidemia with a crude odds ratio (COR) of 0.906 (95%CI=0.786-1.045). Conclusion: Morphine dependency was significantly related to MI, but its risk factors were not significantly associated with morphine dependency. The increasing prevalence of opioid abuse in developing countries may be a reason for the growing incidence of MI in younger ages and individuals with no risk factors. Besides, physicians should consider the presence of impurities in morphine-based opioids and its possible effects on health.

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