scholarly journals 3D Whole Heart Imaging for Congenital Heart Disease

2017 ◽  
Vol 5 ◽  
Author(s):  
Gerald Greil ◽  
Animesh (Aashoo) Tandon ◽  
Miguel Silva Vieira ◽  
Tarique Hussain
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Imaging ◽  
Whole Heart Imaging ◽  
Whole Heart

scholarly journals Dual-phase whole-heart imaging using image navigation in congenital heart disease

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Danielle M. Moyé ◽  
Tarique Hussain ◽  
Rene M. Botnar ◽  
Animesh Tandon ◽  
Gerald F. Greil ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Dual Phase ◽  
Heart Imaging ◽  
Image Navigation ◽  
Whole Heart Imaging ◽  
Whole Heart

Congenital Heart Disease in Children: Coronary MR Angiography during Systole and Diastole with Dual Cardiac Phase Whole-Heart Imaging

Radiology ◽  
2011 ◽  
Vol 260 (1) ◽  
pp. 232-240 ◽  
Author(s):  
Sergio Uribe ◽  
Tarique Hussain ◽  
Israel Valverde ◽  
Cristian Tejos ◽  
Pablo Irarrazaval ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Mr Angiography ◽  
Congenital Heart ◽  
Cardiac Phase ◽  
Heart Imaging ◽  
Whole Heart Imaging ◽  
Whole Heart ◽  
Coronary Mr Angiography

scholarly journals Multiscale cardiac imaging to capture the whole heart and its internal cellular architecture, with applications to congenital heart disease

2020 ◽  
Author(s):  
Graham Rykiel ◽  
Claudia S. López ◽  
Jessica L. Riesterer ◽  
Ian Fries ◽  
Sanika Deosthali ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Defects ◽  
Three Dimensional ◽  
Morphological Structure ◽  
Cardiac Contraction ◽  
Micro Computed Tomography ◽  
Correlative Imaging ◽  
Whole Heart

AbstractEfficient cardiac pumping depends on the morphological structure of the heart, but also on its sub-cellular (ultrastructural) architecture, which enables cardiac contraction. In cases of congenital heart defects, localized sub-cellular disruptions in architecture that increase the risk of heart failure are only starting to be discovered. This is in part due to a lack of technologies that can image the three dimensional (3D) heart structure, assessing malformations; and its ultrastructure, assessing disruptions. We present here a multiscale, correlative imaging procedure that achieves high-resolution images of the whole heart, using 3D micro-computed tomography (micro-CT); and its ultrastructure, using 3D scanning electron microscopy (SEM). This combination of technologies has not been possible before in imaging the same cardiac sample due to the heart large size, even when studying small fetal and neonatal animal models (~5×5×5mm3). Here, we achieved uniform fixation and staining of the whole heart, without losing ultrastructural preservation (at the nm resolution range). Our approach enables multiscale studies of cardiac architecture in models of congenital heart disease and beyond.

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