Beyond the Biomarker: Understanding the Diverse Roles of Human Epididymis Protein 4 in the Pathogenesis of Epithelial Ovarian Cancer

Diagnostic performance of human epididymis protein 4 compared to a combination of biophysical and biochemical markers to differentiate ovarian endometriosis from epithelial ovarian cancer in premenopausal women

Journal of Obstetrics and Gynaecology Research ◽

10.1111/jog.13466 ◽

2017 ◽

Vol 43 (12) ◽

pp. 1870-1879 ◽

Cited By ~ 2

Author(s):

Tanja Nikolova ◽

Radomir Zivadinovic ◽

Nina Evtimovska ◽

Violeta Klisarovska ◽

Marko Stanojevic ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Biochemical Markers ◽

Diagnostic Performance ◽

Premenopausal Women ◽

Ovarian Endometriosis ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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Human epididymis protein 4 increases specificity for the detection of invasiive epithelial ovarian cancer in premenopausal women presenting with an adnexal mass

Gynecologic Oncology ◽

10.1016/j.ygyno.2010.12.167 ◽

2011 ◽

Vol 120 ◽

pp. S69-S70

Author(s):

K. Holcomb ◽

C. Miller ◽

Z. Vucetic ◽

R. Knapp

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Adnexal Mass ◽

Premenopausal Women ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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Does risk for ovarian malignancy algorithm excel human epididymis protein 4 and ca125 in predicting epithelial ovarian cancer: A meta-analysis

BMC Cancer ◽

10.1186/1471-2407-12-258 ◽

2012 ◽

Vol 12 (1) ◽

Cited By ~ 55

Author(s):

Fake Li ◽

Ruxiu Tie ◽

Kai Chang ◽

Feng Wang ◽

Shaoli Deng ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Meta Analysis ◽

Ovarian Malignancy ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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1315 Clinical role of human epididymis protein 4 (HE4) in epithelial ovarian cancer

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(09)70488-4 ◽

2009 ◽

Vol 7 (2) ◽

pp. 143

Author(s):

E. Bandiera ◽

M. Ragnoli ◽

L. Zanotti ◽

E. Bignotti ◽

C. Romani ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Clinical Role ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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Utility of Comprehensive Serum Glycopeptide Spectra Analysis (CSGSA) for the Detection of Early Stage Epithelial Ovarian Cancer

Cancers ◽

10.3390/cancers12092374 ◽

2020 ◽

Vol 12 (9) ◽

pp. 2374

Author(s):

Koji Matsuo ◽

Kazuhiro Tanabe ◽

Masaru Hayashi ◽

Masae Ikeda ◽

Miwa Yasaka ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Diagnostic Performance ◽

Screening Tool ◽

Early Stage ◽

Cancer Antigen 125 ◽

Cancer Antigen ◽

Spectra Analysis ◽

Human Epididymis Protein 4 ◽

Human Epididymis

Comprehensive serum glycopeptide spectra analysis (CSGSA) evaluates >10,000 serum glycopeptides and identifies unique glycopeptide peaks and patterns via supervised orthogonal partial least-squares discriminant modeling. CSGSA was more accurate than cancer antigen 125 (CA125) or human epididymis protein 4 (HE4) for detecting early stage epithelial ovarian cancer. Combined CSGSA, CA125, and HE4 had improved diagnostic performance. Thus, CSGSA may be a useful screening tool for detecting early stage epithelial ovarian cancer.

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Clinical value of human epididymis protein 4 and the Risk of Ovarian Malignancy Algorithm in differentiating borderline pelvic tumors from epithelial ovarian cancer in early stages

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/j.ejogrb.2015.09.008 ◽

2015 ◽

Vol 194 ◽

pp. 141-146 ◽

Cited By ~ 6

Author(s):

Beata Kotowicz ◽

Malgorzata Fuksiewicz ◽

Piotr Sobiczewski ◽

Beata Spiewankiewicz ◽

Joanna Jonska-Gmyrek ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Ovarian Malignancy ◽

Clinical Value ◽

Human Epididymis Protein 4 ◽

Human Epididymis ◽

Early Stages ◽

Pelvic Tumors

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Prognostic significance of human epididymis protein 4 in epithelial ovarian cancer

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/j.ejogrb.2011.05.021 ◽

2011 ◽

Vol 158 (2) ◽

pp. 338-342 ◽

Cited By ~ 24

Author(s):

Jiheum Paek ◽

San-Hui Lee ◽

Ga-Won Yim ◽

Maria Lee ◽

Young-Jae Kim ◽

...

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Prognostic Significance ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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Human Epididymis Protein 4 and Lewis y Enhance Chemotherapeutic Resistance in Epithelial Ovarian Cancer Through the p38 MAPK Pathway

Advances in Therapy ◽

10.1007/s12325-021-01941-1 ◽

2021 ◽

Author(s):

Jian Gao ◽

Liancheng Zhu ◽

Huiyu Zhuang ◽

Bei Lin

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

P38 Mapk ◽

Mapk Pathway ◽

Chemotherapeutic Resistance ◽

Human Epididymis Protein 4 ◽

Human Epididymis ◽

P38 Mapk Pathway ◽

Lewis Y

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Serum Human Epididymis Protein 4 and Risk for Ovarian Malignancy Algorithm as New Diagnostic and Prognostic Tools for Epithelial Ovarian Cancer Management

Yearbook of Obstetrics Gynecology and Women s Health ◽

10.1016/j.yobg.2012.06.178 ◽

2012 ◽

Vol 2012 ◽

pp. 415-417

Author(s):

L.P. Shulman

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Ovarian Malignancy ◽

Human Epididymis Protein 4 ◽

Cancer Management ◽

Human Epididymis

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The role of human epididymis protein 4 in the diagnosis of epithelial ovarian cancer

Clinical & Translational Oncology ◽

10.1007/s12094-015-1365-0 ◽

2015 ◽

Vol 18 (3) ◽

pp. 233-239 ◽

Cited By ~ 7

Author(s):

L.-T. Jia ◽

Y.-C. Zhang ◽

J. Li ◽

Y. Tian ◽

J.-F. Li

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Human Epididymis Protein 4 ◽

Human Epididymis

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