scholarly journals Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient

2012 ◽  
Vol 2 ◽  
Author(s):  
Kevin G. Phillips ◽  
Anand Kolatkar ◽  
Kathleen J. Rees ◽  
Rachel Rigg ◽  
Dena Marrinucci ◽  
...  
2014 ◽  
Vol 136 (3) ◽  
pp. 656-667 ◽  
Author(s):  
Vanessa Dumeaux ◽  
Josie Ursini‐Siegel ◽  
Arnar Flatberg ◽  
Hans E. Fjosne ◽  
Jan‐Ole Frantzen ◽  
...  

2008 ◽  
Vol 68 (10) ◽  
pp. 3618-3623 ◽  
Author(s):  
Ulrika Svenson ◽  
Katarina Nordfjäll ◽  
Birgitta Stegmayr ◽  
Jonas Manjer ◽  
Peter Nilsson ◽  
...  

Blood ◽  
1976 ◽  
Vol 47 (3) ◽  
pp. 381-388 ◽  
Author(s):  
JM Goldman ◽  
KH Th'ng ◽  
D Catovsky ◽  
DA Galton

The production of colony-stimulating factor (CSF) by the peripheral blood cells of untreated patients with acute myeloid leukemia (AML) was measured in the agar culture system using normal human bone marrow as the source of colony-forming units (CFUc). CSF production was found to be variable and was related to the morphologic subtype of AML--cells from patients with monocytic leukemia produced normal or large quantities of CSF, while (with one exception) those from patients with myeloblastic leukemia produced little or no CSF. There was a general relationship between CSF production and serum lysozyme levels. Attempts to demonstrate a consistent inhibitory effect exerted by leukemic peripheral blood cells on normal leukopoiesis in vitro were negative. Results instead suggested that the addition to the feeder layer of cells from patients with monocytic leukemia could raise CSF levels above those obtained with normal peripheral blood leukocytes alone, possibly by recruiting additional CFUc from normal marrow.


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