scholarly journals A Re-Examination of Hebbian-Covariance Rules and Spike Timing-Dependent Plasticity in Cat Visual Cortex in vivo

2010 ◽  
Vol 2 ◽  
Author(s):  
Yves Frégnac ◽  
Marc Pananceau ◽  
Alice René ◽  
Nazyed Huguet ◽  
Olivier Marre ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Spike Timing ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity ◽  
Cat Visual Cortex

Spike Timing-Dependent Plasticity: From Synapse to Perception

2006 ◽  
Vol 86 (3) ◽  
pp. 1033-1048 ◽  
Author(s):  
Yang Dan ◽  
Mu-Ming Poo
Keyword(s):  
Neuronal Excitability ◽  
Human Perception ◽  
Long Term Potentiation ◽  
Spike Timing ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity ◽  
Functional Changes

Information in the nervous system may be carried by both the rate and timing of neuronal spikes. Recent findings of spike timing-dependent plasticity (STDP) have fueled the interest in the potential roles of spike timing in processing and storage of information in neural circuits. Induction of long-term potentiation (LTP) and long-term depression (LTD) in a variety of in vitro and in vivo systems has been shown to depend on the temporal order of pre- and postsynaptic spiking. Spike timing-dependent modification of neuronal excitability and dendritic integration was also observed. Such STDP at the synaptic and cellular level is likely to play important roles in activity-induced functional changes in neuronal receptive fields and human perception.

Spike-Timing-Dependent Plasticity in Balanced Random Networks

2007 ◽  
Vol 19 (6) ◽  
pp. 1437-1467 ◽  
Author(s):  
Abigail Morrison ◽  
Ad Aertsen ◽  
Markus Diesmann
Keyword(s):  
Cortical Neurons ◽  
Random Network ◽  
Theoretical Models ◽  
Relative Strength ◽  
Spike Timing ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity ◽  
Weight Trajectories ◽  
Membrane Potential Fluctuations

The balanced random network model attracts considerable interest because it explains the irregular spiking activity at low rates and large membrane potential fluctuations exhibited by cortical neurons in vivo. In this article, we investigate to what extent this model is also compatible with the experimentally observed phenomenon of spike-timing-dependent plasticity (STDP). Confronted with the plethora of theoretical models for STDP available, we reexamine the experimental data. On this basis, we propose a novel STDP update rule, with a multiplicative dependence on the synaptic weight for depression, and a power law dependence for potentiation. We show that this rule, when implemented in large, balanced networks of realistic connectivity and sparseness, is compatible with the asynchronous irregular activity regime. The resultant equilibrium weight distribution is unimodal with fluctuating individual weight trajectories and does not exhibit development of structure. We investigate the robustness of our results with respect to the relative strength of depression. We introduce synchronous stimulation to a group of neurons and demonstrate that the decoupling of this group from the rest of the network is so severe that it cannot effectively control the spiking of other neurons, even those with the highest convergence from this group.

scholarly journals Environmental enrichment shapes striatal spike-timing-dependent plasticity in vivo

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Teresa Morera-Herreras ◽  
Yves Gioanni ◽  
Sylvie Perez ◽  
Gaetan Vignoud ◽  
Laurent Venance
Keyword(s):  
Failure Rate ◽  
Environmental Enrichment ◽  
Hebbian Learning ◽  
Learning Rule ◽  
Spike Timing ◽  
Long Term Effects ◽  
Spike Timing Dependent Plasticity ◽  
Temporal Window ◽  
Dependent Plasticity

AbstractBehavioural experience, such as environmental enrichment (EE), induces long-term effects on learning and memory. Learning can be assessed with the Hebbian paradigm, such as spike-timing-dependent plasticity (STDP), which relies on the timing of neuronal activity on either side of the synapse. Although EE is known to control neuronal excitability and consequently spike timing, whether EE shapes STDP remains unknown. Here, using in vivo long-duration intracellular recordings at the corticostriatal synapses we show that EE promotes asymmetric anti-Hebbian STDP, i.e. spike-timing-dependent-potentiation (tLTP) for post-pre pairings and spike-timing-dependent-depression (tLTD) for pre-post pairings, whereas animals grown in standard housing show mainly tLTD and a high failure rate of plasticity. Indeed, in adult rats grown in standard conditions, we observed unidirectional plasticity (mainly symmetric anti-Hebbian tLTD) within a large temporal window (~200 ms). However, rats grown for two months in EE displayed a bidirectional STDP (tLTP and tLTD depending on spike timing) in a more restricted temporal window (~100 ms) with low failure rate of plasticity. We also found that the effects of EE on STDP characteristics are influenced by the anaesthesia status: the deeper the anaesthesia, the higher the absence of plasticity. These findings establish a central role for EE and the anaesthetic regime in shaping in vivo, a synaptic Hebbian learning rule such as STDP.

scholarly journals On Spike-Timing-Dependent-Plasticity, Memristive Devices, and Building a Self-Learning Visual Cortex

2011 ◽  
Vol 5 ◽  
Author(s):  
Carlos Zamarreño-Ramos ◽  
Luis A. Camuñas-Mesa ◽  
Jose A. Pérez-Carrasco ◽  
Timothée Masquelier ◽  
Teresa Serrano-Gotarredona ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Spike Timing ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity ◽  
Self Learning

scholarly journals How to train a neuron

eLife ◽  
2013 ◽  
Vol 2 ◽  
Author(s):  
Rui P Costa ◽  
Alanna J Watt ◽  
P Jesper Sjöström
Keyword(s):  
Visual Cortex ◽  
Learning Rule ◽  
Spike Timing ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity ◽  
Visual Cortex Neurons ◽  
Response Preferences

A cellular learning rule known as spike-timing-dependent plasticity can form, reshape and erase the response preferences of visual cortex neurons.

Sign in / Sign up

Export Citation Format

Share Document