scholarly journals Adverse Effects of the Apolipoprotein E ε4 Allele on Episodic Memory, Task Switching and Gray Matter Volume in Healthy Young Adults

2017 ◽  
Vol 11 ◽  
Author(s):  
Jianfei Nao ◽  
Hongzan Sun ◽  
Qiushi Wang ◽  
Shuang Ma ◽  
Shuo Zhang ◽  
...  
Keyword(s):  
Young Adults ◽  
Adverse Effects ◽  
Episodic Memory ◽  
Apolipoprotein E ◽  
Task Switching ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Memory Task ◽  
Matter Volume ◽  
Ε4 Allele

scholarly journals The Correlation Between Gray Matter Volume and Verbal Episodic Memory Encoding

2021 ◽  
Vol 168 ◽  
pp. S209
Author(s):  
Jing Yan ◽  
Wenjuan Li ◽  
Tingting Zhang ◽  
Junjun Zhang ◽  
Zhenlan Jin ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Memory Encoding ◽  
Matter Volume ◽  
Verbal Episodic Memory

scholarly journals Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. T66-T71 ◽  
Author(s):  
Akemi Tomoda ◽  
Hanako Suzuki ◽  
Keren Rabi ◽  
Yi-Shin Sheu ◽  
Ann Polcari ◽  
...  
Keyword(s):  
Young Adults ◽  
Corporal Punishment ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume ◽  
Prefrontal Cortical ◽  
Cortical Gray Matter

T83. Subjective Response to Alcohol in Young Adults With Bipolar Disorder and Associated Frontolimbic Gray Matter Volume and Alcohol Use

2019 ◽  
Vol 85 (10) ◽  
pp. S160-S161
Author(s):  
Valeria Tretyak ◽  
Dylan Kirsch ◽  
Sepeadeh Radpour ◽  
Wade Weber ◽  
Stephen Strakowski ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Young Adults ◽  
Alcohol Use ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Subjective Response ◽  
Matter Volume

scholarly journals Lower regional gray matter volume in the absence of higher cortical amyloid burden in late-life depression

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Akihiro Takamiya ◽  
Thomas Vande Casteele ◽  
Michel Koole ◽  
François-Laurent De Winter ◽  
Filip Bouckaert ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Gray Matter ◽  
Memory Function ◽  
Gray Matter Volume ◽  
Verbal Learning ◽  
Late Life ◽  
Amyloid Deposition ◽  
Elderly Subjects ◽  
Late Life Depression ◽  
Matter Volume

AbstractLate-life depression (LLD) is associated with a risk of developing Alzheimer’s disease (AD). However, the role of AD-pathophysiology in LLD, and its association with clinical symptoms and cognitive function are elusive. In this study, one hundred subjects underwent amyloid positron emission tomography (PET) imaging with [18F]-flutemetamol and structural MRI: 48 severely depressed elderly subjects (age 74.1 ± 7.5 years, 33 female) and 52 age-/gender-matched healthy controls (72.4 ± 6.4 years, 37 female). The Geriatric Depression Scale (GDS) and Rey Auditory Verbal Learning Test (RAVLT) were used to assess the severity of depressive symptoms and episodic memory function respectively. Amyloid deposition was quantified using the standardized uptake value ratio. Whole-brain voxel-wise comparisons of amyloid deposition and gray matter volume (GMV) between LLD and controls were performed. Multivariate analysis of covariance was conducted to investigate the association of regional differences in amyloid deposition and GMV with clinical factors, including GDS and RAVLT. As a result, there were no significant group differences in amyloid deposition. In contrast, LLD showed significant lower GMV in the left temporal and parietal region. GMV reduction in the left temporal region was associated with episodic memory dysfunction, but not with depression severity. Regional GMV reduction was not associated with amyloid deposition. LLD is associated with lower GMV in regions that overlap with AD-pathophysiology, and which are associated with episodic memory function. The lack of corresponding associations with amyloid suggests that lower GMV driven by non-amyloid pathology may play a central role in the neurobiology of LLD presenting as a psychiatric disorder.Trial registration: European Union Drug Regulating Authorities Clinical Trials identifier: EudraCT 2009-018064-95.

scholarly journals Asymmetry Map of Human Brain in Young Adults

2020 ◽  
Author(s):  
Maryam Malekzadeh ◽  
Alireza Kashani
Keyword(s):  
Young Adults ◽  
White Matter ◽  
Human Brain ◽  
Surface Area ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cortical Surface ◽  
Cortical Surface Area ◽  
Matter Volume ◽  
Cortical Regions

AbstractAlthough, asymmetry is a central organizational aspect of human brain, it has not been clearly described yet. Here, we have studied structural brain asymmetry in 1113 young adults using data obtained from Human Connectome Project. A significant rightward asymmetry in mean global cerebral cortical thickness, surface area and gray matter volume as well as volumes of cerebral white matter, cerebellar cortex and white matter, hippocampus, putamen, caudate nucleus, nucleus accumbens and amygdala was observed. Thalamus showed a leftward asymmetry. Regionally, most cerebral cortical regions show a significant rightward asymmetry in thickness. However, cortical surface area and gray matter volume are more evenly distributed between two hemispheres with almost half of the regions showing a leftward asymmetry. In addition, a strong correlation between cortical surface area and gray matter volume as well as their asymmetry indices was noted which results in concordant asymmetry patterns between cortical surface area and gray matter volume in most cortical regions.

scholarly journals Changes in the serum metabolite profile correlate with decreased brain gray matter volume in moderate-to-heavy drinking young adults

Alcohol ◽  
2019 ◽  
Vol 75 ◽  
pp. 89-97 ◽  
Author(s):  
Noora Heikkinen ◽  
Olli Kärkkäinen ◽  
Eila Laukkanen ◽  
Virve Kekkonen ◽  
Outi Kaarre ◽  
...  
Keyword(s):  
Young Adults ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Heavy Drinking ◽  
Metabolite Profile ◽  
Matter Volume
Sign in / Sign up

Export Citation Format

Share Document