scholarly journals Does Co-Morbid Obsessive–Compulsive Disorder Modify the Abnormal Language Processing in Schizophrenia Patients? An fMRI Study

2014 ◽  
Vol 8 ◽  
Author(s):  
Maya Bleich-Cohen ◽  
Michael Poyurovsky ◽  
Talma Hendler ◽  
Ronit Weizman ◽  
Haggai Sharon
Keyword(s):  
Language Processing ◽  
Compulsive Disorder ◽  
Fmri Study

Differential lateralization in first-versus second-language processing: An fMRI study

2001 ◽  
Author(s):  
Thad Polk ◽  
Charles Behensky ◽  
Heather Pond ◽  
Stefan Frisch ◽  
Marilyn Shatz ◽  
...  
Keyword(s):  
Second Language ◽  
Language Processing ◽  
Second Language Processing ◽  
Fmri Study

scholarly journals Neurocognitive mechanisms for processing inflectional and derivational complexity in English

Psihologija ◽  
2013 ◽  
Vol 46 (4) ◽  
pp. 439-454 ◽  
Author(s):  
Mirjana Bozic ◽  
William Marslen-Wilson
Keyword(s):  
Lexical Access ◽  
Language Processing ◽  
Current Paper ◽  
Present Evidence ◽  
Morphological Complexity ◽  
Fmri Study ◽  
Complex Words ◽  
Whole Word ◽  
Processing Network

In the current paper we discuss the mechanisms that underlie the processing of inflectional and derivational complexity in English. We address this issue from a neurocognitive perspective and present evidence from a new fMRI study that the two types of morphological complexity engage the language processing network in different ways. The processing of inflectional complexity selectively activates a left-lateralised frontotemporal system, specialised for combinatorial grammatical computations, while derivational complexity primarily engages a distributed bilateral system, argued to support whole-word, stem based lexical access. We discuss the implications of our findings for theories of the processing and representation of morphologically complex words.

scholarly journals Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior

2019 ◽  
Vol 116 (9) ◽  
pp. 3799-3804 ◽  
Author(s):  
Tingting Sun ◽  
Zihua Song ◽  
Yanghua Tian ◽  
Wenbo Tian ◽  
Chunyan Zhu ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Obsessive Compulsive Disorder ◽  
Medial Prefrontal Cortex ◽  
Basolateral Amygdala ◽  
Obsessive Compulsive ◽  
Neuronal Tracing ◽  
Compulsive Disorder ◽  
Glutamatergic Neurons ◽  
Fmri Study ◽  
Checking Behavior

Obsessive-compulsive disorder (OCD) affects ∼1 to 3% of the world’s population. However, the neural mechanisms underlying the excessive checking symptoms in OCD are not fully understood. Using viral neuronal tracing in mice, we found that glutamatergic neurons from the basolateral amygdala (BLAGlu) project onto both medial prefrontal cortex glutamate (mPFCGlu) and GABA (mPFCGABA) neurons that locally innervate mPFCGlu neurons. Next, we developed an OCD checking mouse model with quinpirole-induced repetitive checking behaviors. This model demonstrated decreased glutamatergic mPFC microcircuit activity regulated by enhanced BLAGlu inputs. Optical or chemogenetic manipulations of this maladaptive circuitry restored the behavioral response. These findings were verified in a mouse functional magnetic resonance imaging (fMRI) study, in which the BLA–mPFC functional connectivity was increased in OCD mice. Together, these findings define a unique BLAGlu→mPFCGABA→Glu circuit that controls the checking symptoms of OCD.

Gender related differences in activated brain areas for language processing: an fMRI study

NeuroImage ◽  
1998 ◽  
Vol 7 (4) ◽  
pp. S159 ◽  
Author(s):  
C.B. Grandin ◽  
W.D. Gaillard ◽  
J.R. Whitnah ◽  
J.R. Petrella ◽  
S.H. Braniecki ◽  
...  
Keyword(s):  
Language Processing ◽  
Brain Areas ◽  
Fmri Study

scholarly journals Amygdala activation and symptom dimensions in obsessive–compulsive disorder

2014 ◽  
Vol 204 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Esther Via ◽  
Narcís Cardoner ◽  
Jesús Pujol ◽  
Pino Alonso ◽  
Marina López-Solà ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Cross Sectional ◽  
Symptom Dimensions ◽  
Compulsive Disorder ◽  
Amygdala Activation ◽  
Fearful Faces ◽  
Fmri Study ◽  
Fear And Anxiety ◽  
Emotional Face

BackgroundDespite knowledge of amygdala involvement in fear and anxiety, its contribution to the pathophysiology of obsessive–compulsive disorder (OCD) remains controversial. In the context of neuroimaging studies, it seems likely that the heterogeneity of the disorder might have contributed to a lack of consistent findings.AimsTo assess the influence of OCD symptom dimensions on amygdala responses to a well-validated emotional face-matching paradigm.MethodCross-sectional functional magnetic resonance imaging (fMRI) study of 67 patients with OCD and 67 age-, gender- and education-level matched healthy controls.ResultsThe severity of aggression/checking and sexual/religious symptom dimensions were significantly associated with heightened amygdala activation in those with OCD when responding to fearful faces, whereas no such correlations were seen for other symptom dimensions.ConclusionsAmygdala functional alterations in OCD appear to be specifically modulated by symptom dimensions whose origins may be more closely linked to putative amygdala-centric processes, such as abnormal fear processing.

Are levels of language processing reflected in neural activation? — an fMRI study

NeuroImage ◽  
2001 ◽  
Vol 13 (6) ◽  
pp. 594
Author(s):  
Mary Rudner ◽  
Jonny Cedefamn ◽  
Ola Friman ◽  
Hans Knutsson ◽  
Peter Lundberg ◽  
...  
Keyword(s):  
Language Processing ◽  
Neural Activation ◽  
Fmri Study

scholarly journals Predictors of treatment response to fluvoxamine in obsessive–compulsive disorder: An fMRI study

2010 ◽  
Vol 44 (4) ◽  
pp. 193-200 ◽  
Author(s):  
Hirokuni Sanematsu ◽  
Tomohiro Nakao ◽  
Takashi Yoshiura ◽  
Maiko Nabeyama ◽  
Osamu Togao ◽  
...  
Keyword(s):  
Treatment Response ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Fmri Study

scholarly journals Erroneously Disgusted: fMRI Study Supports Disgust-Related Neural Reuse in Obsessive-Compulsive Disorder (OCD)

2019 ◽  
Vol 13 ◽  
Author(s):  
Kathrin Viol ◽  
Benjamin Aas ◽  
Anna Kastinger ◽  
Martin Kronbichler ◽  
Helmut Johannes Schöller ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Fmri Study ◽  
Neural Reuse
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