scholarly journals Neurocognitive and Quality of Life Improvements Associated With Aerobic Training for Individuals With Persistent Symptoms After Mild Traumatic Brain Injury: Secondary Outcome Analysis of a Pilot Randomized Clinical Trial

2019 ◽  
Vol 10 ◽  
Author(s):  
Emily Gladstone ◽  
Megan E. Narad ◽  
Fadhil Hussain ◽  
Catherine C. Quatman-Yates ◽  
Jason Hugentobler ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Aerobic Training ◽  
Secondary Outcome ◽  
Outcome Analysis ◽  
Persistent Symptoms

scholarly journals Neuromodulation for Mild Traumatic Brain Injury Rehabilitation: A Systematic Review

2020 ◽  
Vol 14 ◽  
Author(s):  
Francesca Buhagiar ◽  
Melinda Fitzgerald ◽  
Jason Bell ◽  
Fiona Allanson ◽  
Carmela Pestell
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Post Intervention ◽  
Persistent Symptoms ◽  
Positive Effects ◽  
The Brain

Background: Mild traumatic brain injury (mTBI) results from an external force to the head or body causing neurophysiological changes within the brain. The number and severity of symptoms can vary, with some individuals experiencing rapid recovery, and others having persistent symptoms for months to years, impacting their quality of life. Current rehabilitation is limited in its ability to treat persistent symptoms and novel approaches are being sought to improve outcomes following mTBI. Neuromodulation is one technique used to encourage adaptive neuroplasticity within the brain.Objective: To systematically review the literature on the efficacy of neuromodulation in the mTBI population.Method: A systematic review was conducted using Medline, Embase, PsycINFO, PsycARTICLES and EBM Review. Preferred Reporting Items for Systematic Reviews and the Synthesis Without Meta-analysis reporting guidelines were used and a narrative review of the selected studies was completed. Fourteen articles fulfilled the inclusion criteria which were published in English, investigating an adult sample and using a pre- and post-intervention design. Studies were excluded if they included non-mild TBI severities, pediatric or older adult populations.Results: Thirteen of fourteen studies reported positive reductions in mTBI symptomatology following neuromodulation. Specifically, improvements were reported in post-concussion symptom ratings, headaches, dizziness, depression, anxiety, sleep disturbance, general disability, cognition, return to work and quality of life. Normalization of working memory activation patterns, vestibular field potentials, hemodynamics of the dorsolateral prefrontal cortex and excessive delta wave activity were also seen. The studies reviewed had several methodological limitations including small, heterogenous samples and varied intervention protocols, limiting generalisability. Further research is required to understand the context in which neuromodulation may be beneficial.Conclusions: While these positive effects are observed, limitations included unequal representation of neuromodulation modalities in the literature, and lack of literature describing the efficacy of neuromodulation on the development or duration of persistent mTBI symptoms. Better clarity regarding neuromodulation efficacy could have a significant impact on mTBI patients, researchers, clinicians, and policy makers, facilitating a more productive post-mTBI population. Despite the limitations, the literature indicates that neuromodulation warrants further investigation. PROSPERO registration number: CRD42020161279.

Neurocognitive and Quality of Life Improvements With Aerobic Training After Persistent Mild Traumatic Brain Injury

2019 ◽  
Vol 100 (10) ◽  
pp. e101
Author(s):  
Emily Gladstone ◽  
Megan Narad ◽  
Fadhil Hussain ◽  
Jason Hugentobler ◽  
Catherine Quatman-Yates ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Aerobic Training

The association between post-concussion symptoms and health-related quality of life in patients with mild traumatic brain injury

Injury ◽  
2019 ◽  
Vol 50 (5) ◽  
pp. 1068-1074 ◽  
Author(s):  
Daphne C. Voormolen ◽  
Suzanne Polinder ◽  
Nicole von Steinbuechel ◽  
Pieter E. Vos ◽  
Maryse C. Cnossen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Factors affecting health-related quality of life among Nepalese adults with mild traumatic brain injury

2021 ◽  
Vol 17 (1) ◽  
pp. 26-32
Author(s):  
Shristi Aryal ◽  
Orapan Thosingha ◽  
Prangtip Chayaput
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Stressful Life Event ◽  
Economic Status ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Background: Mild traumatic brain injury (MTBI) is a stressful life event. Most patients recover, but a subset of patients experience somatic, cognitive and behavioural symptoms that affect health-related quality of life (HRQOL). Aims: To identify the level impact on HRQOL and to examine the associated factors of HRQOL among patients with MTBI. Methods: This was a correlational predictive study. Findings: The mean age of the participants was 33.89 years, with a range from 18 to 62 years. HRQOL was at amoderate level. In multiple regression analysis, social support (β = .419, p = .000), PCS severity (β = -.245, p = .003) and economic status (β = .167, p = .035) accounted for 36.3% of explained variance on HRQOL. Conclusions: Post-concussion symptoms after discharge should be evaluated, and patients' need for support must be thoroughly assessed.

scholarly journals Mild traumatic brain injury recovery: a growth curve modelling analysis over 2 years

2020 ◽  
Vol 267 (11) ◽  
pp. 3223-3234 ◽  
Author(s):  
Ellen L. Carroll ◽  
Joanne G. Outtrim ◽  
Faye Forsyth ◽  
Anne E. Manktelow ◽  
Peter J. A. Hutchinson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Growth Curve ◽  
Well Being ◽  
Longitudinal Assessment ◽  
Major Trauma Centre ◽  
Over Time

Abstract Background An improved understanding of the trajectory of recovery after mild traumatic brain injury is important to be able to understand individual patient outcomes, for longitudinal patient care and to aid the design of clinical trials. Objective To explore changes in health, well-being and cognition over the 2 years following mTBI using latent growth curve (LGC) modelling. Methods Sixty-one adults with mTBI presenting to a UK Major Trauma Centre completed comprehensive longitudinal assessment at up to five time points after injury: 2 weeks, 3 months, 6 months, 1 year and 2 years. Results Persisting problems were seen with neurological symptoms, cognitive issues and poor quality of life measures including 28% reporting incomplete recovery on the Glasgow Outcome Score Extended at 2 years. Harmful drinking, depression, psychological distress, disability, episodic memory and working memory did not improve significantly over the 2 years following injury. For other measures, including the Rivermead Post-Concussion Symptoms and Quality of Life after Brain Injury (QOLIBRI), LGC analysis revealed significant improvement over time with recovery tending to plateau at 3–6 months. Interpretation Significant impairment may persist as late as 2 years after mTBI despite some recovery over time. Longitudinal analyses which make use of all available data indicate that recovery from mTBI occurs over a longer timescale than is commonly believed. These findings point to the need for long-term management of mTBI targeting individuals with persisting impairment.

Longitudinal patterns of behavior, cognition, and quality of life after mild traumatic brain injury in children: BIONIC study findings

Brain Injury ◽  
2019 ◽  
Vol 33 (7) ◽  
pp. 884-893 ◽  
Author(s):  
Kelly M. Jones ◽  
Philip Prah ◽  
Nicola Starkey ◽  
Alice Theadom ◽  
Suzanne Barker-Collo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Longitudinal Patterns ◽  
Patterns Of Behavior
Sign in / Sign up

Export Citation Format

Share Document