scholarly journals In vitro Magnetic Stimulation: A Simple Stimulation Device to Deliver Defined Low Intensity Electromagnetic Fields

2016 ◽  
Vol 10 ◽  
Author(s):  
Stephanie Grehl ◽  
David Martina ◽  
Catherine Goyenvalle ◽  
Zhi-De Deng ◽  
Jennifer Rodger ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Magnetic Stimulation ◽  
Low Intensity

scholarly journals Repetitive low intensity magnetic field stimulation in a neuronal cell line: A metabolomics study

2018 ◽  
Author(s):  
Ivan Hong ◽  
Andrew Garrett ◽  
Garth Maker ◽  
Ian Mullaney ◽  
Jennifer Rodger ◽  
...  
Keyword(s):  
Cell Line ◽  
Magnetic Stimulation ◽  
Neuronal Excitability ◽  
Therapeutic Potential ◽  
Neuronal Cell ◽  
Neural Tissue ◽  
Gaba Release ◽  
Low Intensity ◽  
Repetitive Magnetic Stimulation

Low intensity repetitive magnetic stimulation of neural tissue modulates neuronal excitability and has promising therapeutic potential in the treatment of neurological disorders. However, the underpinning cellular and biochemical mechanisms remain poorly understood. This study investigates the behavioural effects of low intensity repetitive magnetic stimulation (LI-rMS) at a cellular and biochemical level. We delivered LI-rMS (10 mT) at 1 Hz and 10 Hz (n=5 wells per group) to B50 rat neuroblastoma cells in vitro for 10 minutes and measured levels of selected metabolites immediately after stimulation. LI-rMS at both frequencies depleted selected tricarboxylic acid (TCA) cycle metabolites without affecting the main energy supplies. Furthermore, LI-rMS effects were frequency-specific with 1 Hz stimulation having stronger effects than 10 Hz. The observed depletion of metabolites was consistent with an increase in GABA release as a result of higher spontaneous activity. Although the absence of organised neural circuits and other cellular contributors (e.g. excitatory neurons and glia) in the B50 cell line limits the degree to which our results can be extrapolated to the human brain, the changes we describe provide novel insights into how LI-rMS modulates neural tissue.

scholarly journals Repetitive low intensity magnetic field stimulation in a neuronal cell line: a metabolomics study

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4501 ◽  
Author(s):  
Ivan Hong ◽  
Andrew Garrett ◽  
Garth Maker ◽  
Ian Mullaney ◽  
Jennifer Rodger ◽  
...  
Keyword(s):  
Cell Line ◽  
Magnetic Stimulation ◽  
Neuronal Excitability ◽  
Therapeutic Potential ◽  
Neuronal Cell ◽  
Neural Tissue ◽  
Gaba Release ◽  
Low Intensity ◽  
Repetitive Magnetic Stimulation

Low intensity repetitive magnetic stimulation of neural tissue modulates neuronal excitability and has promising therapeutic potential in the treatment of neurological disorders. However, the underpinning cellular and biochemical mechanisms remain poorly understood. This study investigates the behavioural effects of low intensity repetitive magnetic stimulation (LI-rMS) at a cellular and biochemical level. We delivered LI-rMS (10 mT) at 1 Hz and 10 Hz to B50 rat neuroblastoma cellsin vitrofor 10 minutes and measured levels of selected metabolites immediately after stimulation. LI-rMS at both frequencies depleted selected tricarboxylic acid (TCA) cycle metabolites without affecting the main energy supplies. Furthermore, LI-rMS effects were frequency-specific with 1 Hz stimulation having stronger effects than 10 Hz. The observed depletion of metabolites suggested that higher spontaneous activity may have led to an increase in GABA release. Although the absence of organised neural circuits and other cellular contributors (e.g., excitatory neurons and glia) in the B50 cell line limits the degree to which our results can be extrapolated to the human brain, the changes we describe provide novel insights into how LI-rMS modulates neural tissue.

Impact of Electromagnetic Radiation on the Human Organism

2016 ◽  
Vol 695 ◽  
pp. 295-302
Author(s):  
Liliana Sachelarie ◽  
Mihaela Păpușa Vasiliu ◽  
Dorina Maria Farcas ◽  
Oana Maria Daraba ◽  
Laura Romila
Keyword(s):  
Magnetic Fields ◽  
Electromagnetic Fields ◽  
Magnetic Stimulation ◽  
Clinical Medicine ◽  
Heart Diseases ◽  
Biological Effects ◽  
Healing Process ◽  
Human Organism ◽  
Brain Functions

Interaction mechanisms and biological effects that different types of radiation could exert upon humans have been studied by many authors. Different studies investigated the reactions of various types of electrical equipment, power lines, mobile phones and other upon humans, their influence on the brain functions, public health or if magnetic fields (MFs) can be used for pain relief. Some authors found out that electromagnetic fields (EMFs) might be a factor which determined a number of chronic illnesses (cancer, heart diseases and sleep disorders) even to low intensity. But on the other side, because the EMFs are part of nature, being radiated by human body and its organs, the quality and intensity of the energy can either support or destroy health. Magnetic fields and electromagnetic fields are useful modalities to treat various pathologies and diseases. A number of clinical studies, in vivo animal experiments and in vitro cellular and membrane researches, suggested that EMFs and MFs stimulation reduce pain and accelerate the healing process. However, EMFs are still not widely used in clinical medicine. It is accepted that pain control occurs via a series of integrated stages, each with particular objectives essential to the tissue/system repairing processes. Electric and magnetic stimulation have been proven to provide beneficial and reproducible healing effects even when other methods have failed. As for the MFs, this is an excellent possibility as a non – invasive method to control and treat pain. Magnetic stimulation of a patient is different from drug treatment. As technology proliferates and people use more and more electronic devices, some researchers suspect EMFs contribute to a subtle assault upon people’s immune system and health. This paper aims to review the way that electromagnetic fields and other types of radiations interaction at molecular level with human organism.

scholarly journals In Vitro Study of Neurochemical Changes Following Low-Intensity Magnetic Stimulation

IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 194363-194372
Author(s):  
Eunbi Ye ◽  
Sooyeon Lee ◽  
Wonbin Park ◽  
Eunkyoung Park ◽  
Dong-Woo Cho ◽  
...  
Keyword(s):  
Magnetic Stimulation ◽  
In Vitro Study ◽  
Vitro Study ◽  
Low Intensity ◽  
Neurochemical Changes

scholarly journals Repetitive low intensity magnetic field stimulation in a neuronal cell line: A metabolomics study

2018 ◽  
Author(s):  
Ivan Hong ◽  
Andrew Garrett ◽  
Garth Maker ◽  
Ian Mullaney ◽  
Jennifer Rodger ◽  
...  
Keyword(s):  
Cell Line ◽  
Magnetic Stimulation ◽  
Neuronal Excitability ◽  
Therapeutic Potential ◽  
Neuronal Cell ◽  
Neural Tissue ◽  
Gaba Release ◽  
Low Intensity ◽  
Repetitive Magnetic Stimulation

Low intensity repetitive magnetic stimulation of neural tissue modulates neuronal excitability and has promising therapeutic potential in the treatment of neurological disorders. However, the underpinning cellular and biochemical mechanisms remain poorly understood. This study investigates the behavioural effects of low intensity repetitive magnetic stimulation (LI-rMS) at a cellular and biochemical level. We delivered LI-rMS (10 mT) at 1 Hz and 10 Hz (n=5 wells per group) to B50 rat neuroblastoma cells in vitro for 10 minutes and measured levels of selected metabolites immediately after stimulation. LI-rMS at both frequencies depleted selected tricarboxylic acid (TCA) cycle metabolites without affecting the main energy supplies. Furthermore, LI-rMS effects were frequency-specific with 1 Hz stimulation having stronger effects than 10 Hz. The observed depletion of metabolites was consistent with an increase in GABA release as a result of higher spontaneous activity. Although the absence of organised neural circuits and other cellular contributors (e.g. excitatory neurons and glia) in the B50 cell line limits the degree to which our results can be extrapolated to the human brain, the changes we describe provide novel insights into how LI-rMS modulates neural tissue.

Biological effects of low-intensity radiofrequency fields and risk assessment for biota

2020 ◽  
Vol 60 (9) ◽  
pp. 592-596
Author(s):  
Elena I. Sarapultseva ◽  
Darya V. Uskalova ◽  
Ksenya V. Ustenko
Keyword(s):  
Radio Frequency ◽  
Electromagnetic Radiation ◽  
Electromagnetic Fields ◽  
Negative Impact ◽  
Biological Effects ◽  
High Sensitivity ◽  
Communication Technologies ◽  
Natural Ecosystems ◽  
Low Intensity ◽  
Different Levels

Despite the fact that there are still conflicting opinions about the damage caused by modern wireless communication technologies, most scientists report on the negative biological effects of low-intensity radio frequency electromagnetic radiation at different levels of the organization of live nature. There is no doubt that there is a need not only for a sanitary and hygienic assessment of man-made electromagnetic effects on humans, but also for an environmental assessment for biota. The purpose of the study was to assess the potential environmental risk of electromagnetic impact in the centimeter range on natural ecosystems. The initial data were the authors' own results in the field of radiobiology of non-ionizing radiation, as well as published of other researchers. The article analyzes the biological effects of radio frequency electromagnetic fields detected in organisms of different systematic groups and levels of organization. The data on the non-thermal biological effects of electromagnetic fields indicate a high sensitivity of different species to this factor. The analyzed research results emphasize the need to take into account the features of non-thermal effects of electromagnetic radiation on biota, since these radiations can have a negative impact on different hierarchical levels in natural ecosystems.

Effect of Four Different Wave of 1.8mT 50Hz Electromagnetic Fields on Proliferation and Differentiation of Osteoblasts In vitro*

2011 ◽  
Vol 38 (10) ◽  
pp. 967-974
Author(s):  
Jian ZHOU ◽  
Hui-Ping MA ◽  
Ke-Ming CHEN ◽  
Bao-Feng GE ◽  
Guo-Zheng CHENG ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Proliferation And Differentiation
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