scholarly journals Noninvasive Stimulation of the Ventromedial Prefrontal Cortex Indicates Valence Ambiguity in Sad Compared to Happy and Fearful Face Processing

2019 ◽  
Vol 13 ◽  
Author(s):  
Constantin Winker ◽  
Maimu A. Rehbein ◽  
Dean Sabatinelli ◽  
Mira Dohn ◽  
Julius Maitzen ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Face Processing ◽  
Ventromedial Prefrontal Cortex ◽  
Fearful Face ◽  
Stimulation Of

Noninvasive stimulation of the ventromedial prefrontal cortex modulates emotional face processing

NeuroImage ◽  
2018 ◽  
Vol 175 ◽  
pp. 388-401 ◽  
Author(s):  
Constantin Winker ◽  
Maimu A. Rehbein ◽  
Dean Sabatinelli ◽  
Mira Dohn ◽  
Julius Maitzen ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Face Processing ◽  
Ventromedial Prefrontal Cortex ◽  
Emotional Face Processing ◽  
Emotional Face ◽  
Stimulation Of

scholarly journals Effect of Deep Brain Stimulation of the ventromedial prefrontal cortex on the noradrenergic system in rats

2018 ◽  
Vol 11 (1) ◽  
pp. 222-230 ◽  
Author(s):  
Sonia Torres-Sanchez ◽  
Laura Perez-Caballero ◽  
Juan A. Mico ◽  
Pau Celada ◽  
Esther Berrocoso
Keyword(s):  
Prefrontal Cortex ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventromedial Prefrontal Cortex ◽  
Noradrenergic System ◽  
Deep Brain ◽  
Stimulation Of

P12 Connectivity-informed concurrent TMS-fMRI for indirect stimulation of the ventromedial prefrontal cortex

2020 ◽  
Vol 131 (4) ◽  
pp. e17
Author(s):  
R. Varatheeswaran ◽  
U. Hassan ◽  
S. Pillen ◽  
P. Lang ◽  
K. Yuen ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Ventromedial Prefrontal Cortex ◽  
Indirect Stimulation ◽  
Stimulation Of

Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature

NeuroImage ◽  
2016 ◽  
Vol 125 ◽  
pp. 422-427 ◽  
Author(s):  
M. Mallar Chakravarty ◽  
Clement Hamani ◽  
Alonso Martinez-Canabal ◽  
Jacob Ellegood ◽  
Christine Laliberté ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventromedial Prefrontal Cortex ◽  
Neuronal Processes ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Noninvasive Stimulation of the Ventromedial Prefrontal Cortex Enhances Pleasant Scene Processing

2017 ◽  
Vol 27 (6) ◽  
pp. 3449-3456 ◽  
Author(s):  
Markus Junghofer ◽  
Constantin Winker ◽  
Maimu A. Rehbein ◽  
Dean Sabatinelli
Keyword(s):  
Prefrontal Cortex ◽  
Ventromedial Prefrontal Cortex ◽  
Scene Processing ◽  
Stimulation Of

fMRI response to automatic and purposeful familiar-face processing in perceptual and nonperceptual cortical regions

2021 ◽  
Vol 125 (4) ◽  
pp. 1058-1067
Author(s):  
Silvia Ubaldi ◽  
Scott L. Fairhall
Keyword(s):  
Prefrontal Cortex ◽  
Face Processing ◽  
Superior Temporal Gyrus ◽  
Brain Regions ◽  
Ventromedial Prefrontal Cortex ◽  
Access To Information ◽  
Selective Activation ◽  
Familiar Face ◽  
Fmri Response ◽  
Cortical Regions

Information is extracted from familiar faces in both automatic and active modes. Using functional MRI, we show: 1) that automatic access results in the selective activation of nonperceptual brain regions, the precuneus, ventromedial prefrontal cortex, and the anterior face patch and amygdala, demonstrating the automaticity of access to information in these regions; 2) selective increases in the activation of the lateral anterior temporal lobe and posterior superior temporal gyrus when biographic information is actively extracted.

Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression

2020 ◽  
Vol 34 (2) ◽  
pp. 167-180 ◽  
Author(s):  
Lea J Mertens ◽  
Matthew B Wall ◽  
Leor Roseman ◽  
Lysia Demetriou ◽  
David J Nutt ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Functional Connectivity ◽  
Face Processing ◽  
Ventromedial Prefrontal Cortex ◽  
Parameter Estimates ◽  
Treatment Resistant Depression ◽  
Imaging Data ◽  
Treatment Resistant ◽  
Therapeutic Mechanisms ◽  
Resistant Depression

Background: Psilocybin has shown promise as a treatment for depression but its therapeutic mechanisms are not properly understood. In contrast to the presumed actions of antidepressants, we recently found increased amygdala responsiveness to fearful faces one day after open-label treatment with psilocybin (25 mg) in 19 patients with treatment-resistant depression, which correlated with treatment efficacy. Aims: Aiming to further unravel the therapeutic mechanisms of psilocybin, the present study extends this basic activation analysis. We hypothesised changed amygdala functional connectivity, more precisely decreased amygdala-ventromedial prefrontal cortex functional connectivity, during face processing after treatment with psilocybin. Methods: Psychophysiological interaction analyses were conducted on functional magnetic resonance imaging data from a classic face/emotion perception task, with the bilateral amygdala and ventromedial prefrontal cortex time-series as physiological regressors. Average parameter estimates (beta weights) of significant clusters were correlated with clinical outcomes at one week. Results: Results showed decreased ventromedial prefrontal cortex-right amygdala functional connectivity during face processing post- (versus pre-) treatment; this decrease was associated with levels of rumination at one week. This effect was driven by connectivity changes in response to fearful and neutral (but not happy) faces. Independent whole-brain analyses also revealed a post-treatment increase in functional connectivity between the amygdala and ventromedial prefrontal cortex to occipital-parietal cortices during face processing. Conclusion: These results are consistent with the idea that psilocybin therapy revives emotional responsiveness on a neural and psychological level, which may be a key treatment mechanism for psychedelic therapy. Future larger placebo-controlled studies are needed to examine the replicability of the current findings.

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