scholarly journals Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task

2015 ◽  
Vol 9 ◽  
Author(s):  
Xilu Jiao ◽  
Kevin D. Beck ◽  
Catherine E. Myers ◽  
Richard J. Servatius ◽  
Kevin C. H. Pang
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Active Avoidance ◽  
Avoidance Task ◽  
Active Avoidance Task

Modeling of Selection of Relevant Cues in Rats: Effects of Task Complexity and Lesions of Medial Prefrontal Cortex

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
J. Svoboda ◽  
K. Blahna ◽  
P. Telensky ◽  
J. Bures ◽  
A. Stuchlik
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Cognitive Processing ◽  
Task Complexity ◽  
Vestibular Stimulation ◽  
Psychiatric Research ◽  
Avoidance Task ◽  
Future Directions ◽  
Place Avoidance ◽  
Selection Of

One of key features of cognitive processing in both humans and animals is to select relevant stimuli. Several rodent spatial paradigms proved to be useful in biological psychiatric research. A place avoidance task has been previously used in animal model of cognitive deficits in psychosis.Here we present modifications of the place avoidance paradigm, assessing the ability of selecting appropriate cues at various levels of task complexity. Moreover, we present a pilot experiment showing an effect of lesion to medial prefrontal cortex (mPFC) on those tasks. Generally, the place avoidance apparatus consists of a circular arena elevated 1m above the floor. Rats are trained to avoid an unmarked forbidden sector, entering which is punished by mild footshocks. The sector can be defined with respect to the room or arena frame, which can be dissociated by arena rotation. Moreover, we studied an ability of rats to avoid the place defined by salient rotating object.The results showed that animals with mPFC lesion were capable of avoiding a place defined either by distal of by proximal cues, similarly as controls. However, both control and mPFC-lesioned rats had difficulties to avoid a place surrounding moving salient object. The performance increased whenever the rat was passively rotated with the arena, suggesting that vestibular stimulation enhanced the directed attention to an object. The poster will discuss the present findings and outline the future directions with emphasis on their utilization in animal models of neuropsychiatric disorders.Supported by GACR grants 309/07/0341 and 309/06/1231.

Effect of seleptine on retrieval of active avoidance task in rats

1998 ◽  
Vol 126 (1) ◽  
pp. 665-666
Author(s):  
N. B. Pankova ◽  
E. V. Nikushkin ◽  
G. S. Chernov
Keyword(s):  
Active Avoidance ◽  
Avoidance Task ◽  
Active Avoidance Task

Effects of asiatic acid on passive and active avoidance task in male Spraque–Dawley rats

2011 ◽  
Vol 134 (2) ◽  
pp. 203-209 ◽  
Author(s):  
M.N. Nasir ◽  
M. Habsah ◽  
I. Zamzuri ◽  
G. Rammes ◽  
J. Hasnan ◽  
...  
Keyword(s):  
Active Avoidance ◽  
Avoidance Task ◽  
Asiatic Acid ◽  
Active Avoidance Task ◽  
Passive And Active Avoidance

Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task

1989 ◽  
Vol 498 (1) ◽  
pp. 195-198 ◽  
Author(s):  
Akira Ohta ◽  
Toshitsugu Hirano ◽  
Hideo Yagi ◽  
Seigo Tanaka ◽  
Masanori Hosokawa ◽  
...  
Keyword(s):  
Active Avoidance ◽  
Behavioral Characteristics ◽  
Avoidance Task ◽  
Active Avoidance Task

scholarly journals Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats

2013 ◽  
Vol 6 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Stefka Valcheva-Kuzmanova ◽  
Miroslav Eftimov ◽  
Iren Beleheva ◽  
Roman Tashev ◽  
Stiliana Beleheva
Keyword(s):  
Learning And Memory ◽  
Active Avoidance ◽  
Fruit Juice ◽  
Training Session ◽  
Brain Regions ◽  
Memory Effects ◽  
Avoidance Task ◽  
Active Avoidance Task ◽  
Aronia Melanocarpa ◽  
Improved Learning

Summary Amnia melanocarpa fruits are one of the richest natural sources of phenolic substances, among them flavonoids, mainly from the subclass of anthocyanins. Flavonoids, which are constituents of Amnia melanocarpa fruit juice, have been found to localize in various brain regions that are important for memory. The aim of the present study was to investigate the learning and memory effects of Amnia melanocarpa fruit juice (AMFJ) in young/healthy male Wistarrats. AMFJ was applied orally for 21 and 30 days at a dose of 10 ml/kg b.w., and comparisons were made with saline-treated (10 ml/kg b.w.) controls. Learning and memory functions were evaluated, using the two-way active avoidance task (shuttle box). Administered for the two treatment periods, the juice significantly increased the number of avoidances on training days 1 and 2, as well as at the retention test (24 h after the 2nd training session). These effects were more pronounced in rats treated with AMFJ for 30 days. The learning and memory effects of AMFJ are probably due to its polyphenolic constituents. The findings from the present study suggest that AMFJ applied subchronically improved learning and memory in young/healthy rats.

Investigations into the neuropharmacological basis of temporal stages of memory formation in mice trained in an active avoidance task

1987 ◽  
Vol 23 (3) ◽  
pp. 239-250 ◽  
Author(s):  
Sheri J.Y. Mizumori ◽  
Damon H. Sakai ◽  
Mark R. Rosenzweig ◽  
Edward L. Bennett ◽  
Peter Wittreich
Keyword(s):  
Active Avoidance ◽  
Memory Formation ◽  
Avoidance Task ◽  
Active Avoidance Task
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