scholarly journals Changes in Neural Activity Underlying Working Memory after Computerized Cognitive Training in Older Adults

2016 ◽  
Vol 8 ◽  
Author(s):  
Erich S. Tusch ◽  
Brittany R. Alperin ◽  
Eliza Ryan ◽  
Phillip J. Holcomb ◽  
Abdul H. Mohammed ◽  
...  
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Cognitive Training ◽  
Neural Activity ◽  
Computerized Cognitive Training

scholarly journals Spontaneous Eye Blinks Predict Executive Functioning in Seniors

2021 ◽  
Author(s):  
Jessika I. V. Buitenweg ◽  
Jaap M. J. Murre ◽  
K. Richard Ridderinkhof
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Executive Functioning ◽  
Cognitive Training ◽  
Functional Decline ◽  
Future Research ◽  
Blink Rate ◽  
Memory Updating ◽  
Age Related ◽  
Working Memory Updating

AbstractAs the world’s population is aging rapidly, cognitive training is an extensively used approach to attempt improvement of age-related cognitive functioning. With increasing numbers of older adults required to remain in the workforce, it is important to be able to reliably predict future functional decline, as well as the individual advantages of cognitive training. Given the correlation between age-related decline and striatal dopaminergic function, we investigated whether eye blink rate (EBR), a non-invasive, indirect indicator of dopaminergic activity, could predict executive functioning (response inhibition, switching and working memory updating) as well as trainability of executive functioning in older adults. EBR was collected before and after a cognitive flexibility training, cognitive training without flexibility, or a mock training. EBR predicted working memory updating performance on two measures of updating, as well as trainability of working memory updating, whereas performance and trainability in inhibition and switching tasks could not be predicted by EBR. Our findings tentatively indicate that EBR permits prediction of working memory performance in older adults. To fully interpret the relationship with executive functioning, we suggest future research should assess both EBR and dopamine receptor availability among seniors.

scholarly journals Effects of multi-domain cognitive training on working memory retrieval in older adults: behavioral and ERP evidence from a Chinese community study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiangfei Hong ◽  
You Chen ◽  
Jijun Wang ◽  
Yuan Shen ◽  
Qingwei Li ◽  
...  
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Training Program ◽  
Cognitive Training ◽  
Local Community ◽  
Training Group ◽  
Event Related Potential ◽  
Control Group ◽  
Baseline Session

AbstractWorking memory (WM) is a fundamental cognitive function that typically declines with age. Previous studies have shown that targeted WM training has the potential to improve WM performance in older adults. In the present study, we investigated whether a multi-domain cognitive training program that was not designed to specifically target WM could improve the behavioral performance and affect the neural activity during WM retrieval in healthy older adults. We assigned healthy older participants (70–78 years old) from a local community into a training group who completed a 3-month multi-domain cognitive training and a control group who only attended health education lectures during the same period. Behavioral and electroencephalography (EEG) data were recorded from participants while performing an untrained delayed match or non-match to category task and a control task at a pre-training baseline session and a post-training follow-up session. Behaviorally, we found that participants in the training group showed a trend toward greater WM performance gains than participants in the control group. Event-related potential (ERP) results suggest that the task-related modulation of P3 during WM retrieval was significantly enhanced at the follow-up session compared with the baseline session, and importantly, this enhancement of P3 modulation was only significant in the training group. Furthermore, no training-related effects were observed for the P2 or N2 component during WM retrieval. These results suggest that the multi-domain cognitive training program that was not designed to specifically target WM is a promising approach to improve WM performance in older adults, and that training-related gains in performance are likely mediated by an enhanced modulation of P3 which might reflect the process of WM updating.

EFFECTS OF COMPUTERIZED COGNITIVE TRAINING ON GAIT SPEED IN COMMUNITY DWELLING OLDER ADULTS, A PILOT STUDY

2016 ◽  
pp. 1-6
Author(s):  
J. Blackwood ◽  
T. Houston
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Gait Speed ◽  
Independent Living ◽  
Functional Decline ◽  
Community Dwelling ◽  
Computerized Cognitive Training ◽  
Home Based ◽  
Improved Function ◽  
Community Dwelling Older Adults

Background: In older adults declines in gait speed have been identified as predictors of functional decline and have been found in those with cognitive dysfunction. Cognitive training interventions that emphasize addressing executive function (EF) have resulted in a transfer effect from training cognitive processes into improved function. However research examining the effects of an EF specific computerized cognitive training (CCT) program on gait speed (GS) is limited. Objectives: To compare the effects of a six week EF specific CCT program on GS in community dwelling older adults using a pretest/posttest experimental design with subgroup comparisons based on a cutoff GS of 1.0m/s. Setting: Home based Participants: Forty independent living older adults (>65 years) without diagnosed cognitive impairment participated in either the intervention or control groups. Intervention: A six week long progressively challenging EF focused CCT program was performed at home. Measurements: Demographic variables, cognitive function (Trail-Making Test Part B) and GS were measured at baseline at week 7. Between group comparisons were completed for the whole sample initially with subgroup comparisons performed based on participants’ initial GS (Slow walkers: GS<1.0m/s; Fast Walkers: GS>1.0m/s). Results: No differences in GS were found for the whole population, but subgroup analyses restricted to slow walkers demonstrated a statistically significant improvement in GS after 6 weeks of CCT (µ =0.33 m/s, p = 0.03). Other outcomes measures were not statistically different at posttest. Conclusions: Older adults who walk at speeds <1.0m/s may benefit from a progressively challenging CCT program when self-administered in the home.

scholarly journals Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
P. Šimko ◽  
M. Pupíková ◽  
M. Gajdoš ◽  
I. Rektorová
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Cognitive Training ◽  
Brain Network ◽  
Resting State Functional Connectivity ◽  
Double Blind ◽  
Sham Stimulation ◽  
Highly Educated ◽  
Fmri Study ◽  
Dorsolateral Prefrontal

Enhancing cognitive functions through noninvasive brain stimulation is of enormous public interest, particularly for the aging population in whom processes such as working memory are known to decline. In a randomized double-blind crossover study, we investigated the acute behavioral and neural aftereffects of bifrontal and frontoparietal transcranial direct current stimulation (tDCS) combined with visual working memory (VWM) training on 25 highly educated older adults. Resting-state functional connectivity (rs-FC) analysis was performed prior to and after each stimulation session with a focus on the frontoparietal control network (FPCN). The bifrontal montage with anode over the left dorsolateral prefrontal cortex enhanced VWM accuracy as compared to the sham stimulation. With the rs-FC within the FPCN, we observed significant stimulation × time interaction using bifrontal tDCS. We found no cognitive aftereffects of the frontoparietal tDCS compared to sham stimulation. Our study shows that a single bifrontal tDCS combined with cognitive training may enhance VWM performance and rs-FC within the relevant brain network even in highly educated older adults.

scholarly journals EFFECT ASSESSMENT OF A COGNITIVE TRAINING PLATFORM IN HEALTHY OLDER ADULTS

2017 ◽  
Vol 5 ◽  
pp. 1032-1035
Author(s):  
Antonia Yaneva ◽  
Nonka Mateva
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Cognitive Functions ◽  
Cognitive Status ◽  
Post Intervention ◽  
Healthy Older Adults ◽  
Computerized Cognitive Training ◽  
Negative Results ◽  
Healthy Elderly ◽  
Traditional Programs

Cognitive interventions, especially cognitive training, may improve cognitive functions in healthy older adults. Computerized cognitive training platforms offer several advantages over traditional programs for cognitive training and stimulation. The focus of this article is the methodology of the studies that apply a particular online training program. We investigate the effectiveness of several studies for cognitive training in healthy elderly people and evaluate reported outcomes and potential bias and what factors determine, influence or contribute to the positive or negative results. The post-intervention scores demonstrate that computerized cognitive training may enhance some cognitive functions and the overall cognitive status but there is need for additional research to prove its effectiveness.

The effectiveness of computerized cognitive training on working memory in a school setting

2020 ◽  
Vol 34 (2) ◽  
pp. 465-471
Author(s):  
Dudley J. Wiest ◽  
Eugene H. Wong ◽  
Jennifer M. Bacon ◽  
Kevin P. Rosales ◽  
Grahamm M. Wiest
Keyword(s):  
Working Memory ◽  
Cognitive Training ◽  
School Setting ◽  
Computerized Cognitive Training

scholarly journals COMPUTERIZED COGNITIVE TRAINING, WITH OR WITHOUT EXERCISE, TO PROMOTE COGNITIVE FUNCTION: A RANDOMIZED TRIAL

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S55-S56
Author(s):  
Lisanne F ten Brinke ◽  
John R Best ◽  
Joey L Chan ◽  
Cheyenne Ghag ◽  
Kirk I Erickson ◽  
...  
Keyword(s):  
Older Adults ◽  
Physical Exercise ◽  
Executive Functions ◽  
Cognitive Training ◽  
Verbal Learning ◽  
Stroop Test ◽  
Community Dwelling ◽  
Computerized Cognitive Training ◽  
Improved Performance ◽  
At Home

Abstract Given the world’s aging population, it is important to identify strategies that promote healthy cognitive aging. Computerized cognitive training (CCT) may be a promising method to combat cognitive decline in older adults. Moreover, physical exercise immediately prior to CCT might provide additional cognitive benefits. We conducted a randomized controlled trial to examine the effect of a CCT intervention, alone or preceded by physical exercise, on memory and executive functions in older adults. 124 community-dwelling older adults aged 65-85 years were randomly assigned to either 8-weeks of: 1) 3x/week group-based CCT plus 3x/week CCT sessions at home; 2) 3x/week group-based CCT combined with a 15-minute brisk walk (Ex-CCT) plus 3x/week Ex-CCT sessions at home; or 3)3x/week group-based sham exercise and education sessions (CON). At baseline and 8-weeks standard neuropsychological tests of verbal memory and learning and executive functions were administered, including the Rey Auditory Verbal Learning Test (RAVLT), Stroop test, Flanker test, Trail Making Tests (TMT B-A), and Dimensional Change Card Sort (DCCS) Test. At trial completion, there were no differences in RAVLT performance. Compared with CON, FBT and Ex-FBT participants significantly improved performance on the Stroop test (p = .001 and p = .023, respectively). Additionally, those randomized to Ex-CCT improved performance on the Flanker test (p = .002), TMT B-A (p = .047), and the DCCS Test (p = .023) compared with BAT. These findings suggest that an 8-week CCT program could benefit executive functions, and that implementing exercise immediately prior to CCT could provide broader benefits.

Efficacy of a computerized cognitive training application for older adults with and without memory impairments

2013 ◽  
Vol 25 (4) ◽  
pp. 411-419 ◽  
Author(s):  
Ana Maseda ◽  
José C. Millán-Calenti ◽  
Laura Lorenzo-López ◽  
Laura Núñez-Naveira
Keyword(s):  
Older Adults ◽  
Cognitive Training ◽  
Memory Impairments ◽  
Computerized Cognitive Training
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