scholarly journals Molecular Characterization and Comparative Genomic Analysis of vB_PaeP_YA3, a Novel Temperate Bacteriophage of Pseudomonas aeruginosa

2020 ◽  
Vol 11 ◽  
Author(s):  
Xinyan Yu ◽  
Jing Xu ◽  
Yu Gu ◽  
Ruiyang Zhang ◽  
Yefei Zhu ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Molecular Characterization ◽  
Genomic Analysis ◽  
Comparative Genomic Analysis ◽  
Comparative Genomic ◽  
Temperate Bacteriophage

scholarly journals AmpDI Is Involved in Expression of the Chromosomal L1 and L2 β-Lactamases of Stenotrophomonas maltophilia

2009 ◽  
Vol 53 (7) ◽  
pp. 2902-2907 ◽  
Author(s):  
Tsuey-Ching Yang ◽  
Yi-Wei Huang ◽  
Rouh-Mei Hu ◽  
Shao-Cheng Huang ◽  
Yu-Tzu Lin
Keyword(s):  
Gene Expression ◽  
Pseudomonas Aeruginosa ◽  
Stenotrophomonas Maltophilia ◽  
Genomic Analysis ◽  
Comparative Genomic Analysis ◽  
Comparative Genomic ◽  
Genomic Context ◽  
One Step ◽  
L1 And L2

ABSTRACT Two ampD homologues, ampD I and ampD II, of Stenotrophomonas maltophilia have been cloned and analyzed. Comparative genomic analysis revealed that the genomic context of the ampD II genes is quite different, whereas that of the ampD I genes is more conserved in S. maltophilia strains. The ampD system of S. maltophilia is distinct from that of the Enterobacteriaceae and Pseudomonas aeruginosa in three respects. (i) AmpDI of S. maltophilia is not encoded in an ampDE operon, in contrast to what happens in the Enterobacteriaceae and P. aeruginosa. (ii) The AmpD systems of the Enterobacteriaceae and P. aeruginosa are generally involved in the regulation of ampR-linked ampC gene expression, while AmpDI of S. maltophilia is responsible for the regulation of two intrinsic β-lactamase genes, of which the L2 gene, but not the L1 gene, is linked to ampR. (iii) S. maltophilia exhibits a one-step L1 and L2 gene derepression model involving ampD I, distinct from the two- or three-step derepression of the Enterobacteriaceae and P. aeruginosa. Moreover, the ampD I and ampD II genes are constitutively expressed and not regulated by the inducer and AmpR protein, and the expression of ampD II is weaker than that of ampD I. Finally, AmpDII is not associated with the derepression of β-lactamases, and its role in S. maltophilia remains unclear.

Comparative genomic analysis of Pseudomonas aeruginosa phage PaMx25 reveals a novel siphovirus group related to phages infecting hosts of different taxonomic classes

2017 ◽  
Vol 162 (8) ◽  
pp. 2345-2355 ◽  
Author(s):  
Víctor Flores ◽  
Omar Sepúlveda-Robles ◽  
Adrián Cazares ◽  
Luis Kameyama ◽  
Gabriel Guarneros
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Genomic Analysis ◽  
Comparative Genomic Analysis ◽  
Comparative Genomic

scholarly journals Comparative Genomic Analysis of 18 Pseudomonas aeruginosa Bacteriophages

2006 ◽  
Vol 188 (3) ◽  
pp. 1184-1187 ◽  
Author(s):  
Tony Kwan ◽  
Jing Liu ◽  
Michael DuBow ◽  
Philippe Gros ◽  
Jerry Pelletier
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Sequence Analysis ◽  
Genomic Analysis ◽  
Comparative Sequence Analysis ◽  
Comparative Genomic Analysis ◽  
Open Reading Frames ◽  
Comparative Genomic ◽  
Comparative Sequence ◽  
Reading Frames

ABSTRACT A genomic analysis of 18 P. aeruginosa phages, including nine newly sequenced DNA genomes, indicates a tremendous reservoir of proteome diversity, with 55% of open reading frames (ORFs) being novel. Comparative sequence analysis and ORF map organization revealed that most of the phages analyzed displayed little relationship to each other.

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