scholarly journals Study of the Regulatory Role of N-Acyl Homoserine Lactones Mediated Quorum Sensing in the Biological Activity of Burkholderia gladioli pv. agaricicola Causing Soft Rot of Agaricus spp.

2019 ◽  
Vol 10 ◽  
Author(s):  
Hazem S. Elshafie ◽  
Giulia Devescovi ◽  
Vittorio Venturi ◽  
Ippolito Camele ◽  
Sabino A. Bufo
Keyword(s):  
Biological Activity ◽  
Quorum Sensing ◽  
Soft Rot ◽  
Regulatory Role ◽  
Homoserine Lactones ◽  
Acyl Homoserine Lactones ◽  
Burkholderia Gladioli

scholarly journals Virulence of Burkholderia mallei Quorum-Sensing Mutants

2013 ◽  
Vol 81 (5) ◽  
pp. 1471-1478 ◽  
Author(s):  
Charlotte Majerczyk ◽  
Loren Kinman ◽  
Tony Han ◽  
Richard Bunt ◽  
E. Peter Greenberg
Keyword(s):  
Quorum Sensing ◽  
Homoserine Lactone ◽  
Mouse Lung ◽  
Depth Information ◽  
Acyl Homoserine Lactone ◽  
Burkholderia Mallei ◽  
Content Type ◽  
Homoserine Lactones ◽  
Acyl Homoserine Lactones

ABSTRACTManyProteobacteriause acyl-homoserine lactone-mediated quorum-sensing (QS) to activate specific sets of genes as a function of cell density. QS often controls the virulence of pathogenic species, and in fact a previous study indicated that QS was important forBurkholderia malleimouse lung infections. To gain in-depth information on the role of QS inB. malleivirulence, we constructed and characterized a mutant ofB. malleistrain GB8 that was unable to make acyl-homoserine lactones. The QS mutant showed virulence equal to that of its wild-type parent in an aerosol mouse infection model, and growth in macrophages was indistinguishable from that of the parent strain. Furthermore, we assessed the role of QS inB. malleiATCC 23344 by constructing and characterizing a mutant strain producing AiiA, a lactonase enzyme that degrades acyl-homoserine lactones. Although acyl-homoserine lactone levels in cultures of this strain are very low, it showed full virulence. Contrary to the previous report, we conclude that QS is not required for acuteB. malleiinfections of mice. QS may be involved in some stage of chronic infections in the natural host of horses, or the QS genes may be remnants of the QS network inB. pseudomalleifrom which this host-adapted pathogen evolved.

scholarly journals Thermoregulation of N-Acyl Homoserine Lactone-Based Quorum Sensing in the Soft Rot Bacterium Pectobacterium atrosepticum

2007 ◽  
Vol 73 (12) ◽  
pp. 4078-4081 ◽  
Author(s):  
Xavier Latour ◽  
St�phanie Diallo ◽  
Sylvie Chevalier ◽  
Dani�le Morin ◽  
Bruno Smadja ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Soft Rot ◽  
Homoserine Lactone ◽  
Transcriptional Level ◽  
Acyl Homoserine Lactone ◽  
Pectobacterium Atrosepticum ◽  
Homoserine Lactones ◽  
Acyl Homoserine Lactones ◽  
Wide Range ◽  
Psychrotolerant Bacterium

ABSTRACT The psychrotolerant bacterium Pectobacterium atrosepticum produces four N-acyl homoserine lactones under a wide range of temperatures. Their thermoregulation differs from that of the exoenzyme production, described as being under quorum-sensing control. A mechanism involved in this thermoregulation consists of controlling N-acyl homoserine lactones synthase production at a transcriptional level.

Growth of Salmonella Enteritidis in the presence of quorum sensing signaling compounds produced by Pseudomonas aeruginosa

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Weijia He ◽  
Huamei Yang ◽  
Xiang Wang ◽  
Hongmei Li ◽  
Qingli Dong
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Salmonella Enteritidis ◽  
Culture Supernatant ◽  
Lag Time ◽  
Bacterial Communication ◽  
Homoserine Lactones ◽  
Positive Effects ◽  
Kinetics Of

Abstract Quorum sensing (QS) can exist in food-related bacteria and potentially affect bacterial growth through acyl-homoserine lactones (AHLs). To verify the role of QS compounds in the cell-free supernatant, this study examined the effect of supernatant extracted from Pseudomonas aeruginosa culture on the growth kinetics of Salmonella Enteritidis. The results showed that the lag time (λ) of S. Enteritidis was apparently reduced (p < 0.05) under the influence of P. aeruginosa culture supernatant compared with the S. Enteritidis culture supernatant. HPLC-MS/MS test demonstrated that AHLs secreted by P. aeruginosa were mainly C14-HSL with a content of 85.71 μg/mL and a small amount of 3-oxo-C12-HSL. In addition, the commercially synthetic C14-HSL had positive effects on the growth of S. Enteritidis, confirming once again that the growth of S. Enteritidis was affected by AHL metabolized by other bacteria and the complexity of bacterial communication.

Influence of the d/l configuration of N-acyl-homoserine lactones (AHLs) and analogues on their Lux-R dependent quorum sensing activity

2018 ◽  
Vol 77 ◽  
pp. 215-222 ◽  
Author(s):  
Si-Zhe Li ◽  
Rui Xu ◽  
Mohammed Ahmar ◽  
Catherine Goux-Henry ◽  
Yves Queneau ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Homoserine Lactones ◽  
Acyl Homoserine Lactones
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