scholarly journals Nitric Oxide Dismutase (nod) Genes as a Functional Marker for the Diversity and Phylogeny of Methane-Driven Oxygenic Denitrifiers

2019 ◽  
Vol 10 ◽  
Author(s):  
Baoli Zhu ◽  
Jiaqi Wang ◽  
Lauren M. Bradford ◽  
Katharina Ettwig ◽  
Baolan Hu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Functional Marker ◽  
Nod Genes

scholarly journals Long-Read Amplicon Sequencing of Nitric Oxide Dismutase (nod) Genes Reveal Diverse Oxygenic Denitrifiers in Agricultural Soils and Lake Sediments

2020 ◽  
Vol 80 (1) ◽  
pp. 243-247 ◽  
Author(s):  
Baoli Zhu ◽  
Zhe Wang ◽  
Dheeraj Kanaparthi ◽  
Susanne Kublik ◽  
Tida Ge ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lake Sediments ◽  
Agricultural Soils ◽  
Amplicon Sequencing ◽  
Nod Genes ◽  
Long Read

scholarly journals A new role for the exhaled nitric oxide as a functional marker of peripheral airway caliber changes: a theoretical study

2018 ◽  
Vol 124 (4) ◽  
pp. 1025-1033 ◽  
Author(s):  
Cyril Karamaoun ◽  
Benoit Haut ◽  
Alain Van Muylem
Keyword(s):  
Nitric Oxide ◽  
Fluid Layer ◽  
Functional Marker ◽  
New Model ◽  
Airway Lumen ◽  
Inflammatory Status ◽  
Airway Caliber ◽  
Peripheral Airway ◽  
Lung Periphery ◽  
Epithelial Wall

Although considered as an inflammation marker, exhaled nitric oxide (FENO) was shown to be sensitive to airway caliber changes to such an extent that it might be considered as a marker of them. It is thus important to understand how these changes and their localization mechanically affect the total NO flux penetrating the airway lumen ( JawNO), and hence FENO, independently from any inflammatory status change. In this work, a new model was used. It simulates NO production, consumption, and diffusion inside the airway epithelium, NO excretion from the epithelial wall into the airway lumen and, finally, its axial transport by diffusion and convection in the airway lumen. This model may also consider the possible presence of a fluid layer coating the epithelial wall. Simulations were performed. They show the great sensitivity of JawNO to peripheral airway caliber changes. Moreover, FENO shows distinct behaviors, depending on the location of the caliber change. Considering a bronchodilation, absence of FENO change was associated with dilation of central airways, FENO increase with dilation down to pre-acinar small airways, and FENO decrease with intra-acinar dilation due to the amplification of the back diffusion flux. The presence of a fluid layer was also shown to play a significant role in FENO changes. Altogether, the present work theoretically supports that specific FENO changes in acute situations are linked to specifically located airway caliber changes in the lung periphery. This opens the way for a new role for FENO as a functional marker of peripheral airway caliber change. NEW & NOTEWORTHY Using a new model of nitric oxide production and transport, allowing realistic simulation of airway caliber change, the present work theoretically supports that specific changes of the molar fraction of nitric oxide in the exhaled air, occurring without any change in the inflammatory status, are linked to specifically located airway caliber changes in the lung periphery. This opens the way for a new role for FENO as a functional marker of peripheral airway caliber change.

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

Nitric Oxide Reduces Pressor Responsiveness During Ovine Hypoadrenocorticism

2001 ◽  
Vol 28 (5-6) ◽  
pp. 459-462
Author(s):  
Pini Orbach ◽  
Charles E Wood ◽  
Maureen Keller-Wood
Keyword(s):  
Nitric Oxide

Nitric oxide synthase and cellac disease

2001 ◽  
Vol 120 (5) ◽  
pp. A684-A684
Author(s):  
I DANIELS ◽  
I MURRAY ◽  
W GODDARD ◽  
R LONG
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Oxide Synthase

Intralipid-induced gastric relaxation in humans is mediated by nitric oxide

2001 ◽  
Vol 120 (5) ◽  
pp. A461-A461
Author(s):  
S KUIKEN ◽  
G TYTGAT ◽  
G BOEKXSTAENS
Keyword(s):  
Nitric Oxide
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