scholarly journals Genetic Relationship, Virulence Factors, Drug Resistance Profile and Biofilm Formation Ability of Vibrio parahaemolyticus Isolated From Mussel

2019 ◽  
Vol 10 ◽  
Author(s):  
Md. Ashrafudoulla ◽  
Md. Furkanur Rahaman Mizan ◽  
Heedae Park ◽  
Kye-Hwan Byun ◽  
Nari Lee ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Virulence Factors ◽  
Genetic Relationship ◽  
Biofilm Formation ◽  
Vibrio Parahaemolyticus ◽  
Resistance Profile ◽  
Drug Resistance Profile

Quorum Sensing – A Stratagem for Conquering Multi-Drug Resistant Pathogens

2020 ◽  
Vol 26 ◽  
Author(s):  
Madison Tonkin ◽  
Shama Khan ◽  
Mohmmad Younus Wani ◽  
Aijaz Ahmad
Keyword(s):  
Drug Resistance ◽  
Quorum Sensing ◽  
Virulence Factors ◽  
Biofilm Formation ◽  
Cell Communication ◽  
Natural Compounds ◽  
Quorum Sensing Inhibitors ◽  
Communication Technique ◽  
Multicellular Organisms ◽  
Chemical Strategies

: Quorum sensing is defined as cell to cell communication between microorganisms, which enables microorganisms to behave as multicellular organisms. Quorum sensing enables many collaborative benefits such as synchronisation of virulence factors and biofilm formation. Both quorum sensing as well as biofilm formation encourage the development of drug resistance in microorganisms. Biofilm formation and quorum sensing are causally linked to each other and play role in the pathogenesis of microorganisms. With the increasing drug resistance against the available antibiotics and antifungal medications, scientists are combining different options to develop new strategies. Such strategies rely on the inhibition of the communication and virulence factors rather than on killing or inhibiting the growth of the microorganisms. This review encompasses the communication technique used by microorganisms, how microorganism resistance is linked to quorum sensing and various chemical strategies to combat quorum sensing and thereby drug resistance. Several compounds have been identified as quorum sensing inhibitors and are known to be effective in reducing resistance as they do not kill the pathogens but rather disrupt their communication. Natural compounds have been identified as anti-quorum sensing agents. However, natural compounds present several related disadvantages. Therefore, the need for the development of synthetic or semi-synthetic compounds has arisen. This review argues that anti-quorum sensing compounds are effective in disrupting quorum sensing and could therefore be effective in reducing microorganism drug resistance.

scholarly journals The Drug Resistance Profile of Mycobacterium abscessus Group Strains from Korea

2014 ◽  
Vol 34 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Seung Heon Lee ◽  
Hee Kyung Yoo ◽  
Seol Hee Kim ◽  
Won-Jung Koh ◽  
Chang Ki Kim ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Mycobacterium Abscessus ◽  
Resistance Profile ◽  
Drug Resistance Profile

scholarly journals In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype

Leukemia ◽  
2004 ◽  
Vol 18 (3) ◽  
pp. 521-529 ◽  
Author(s):  
N L Ramakers-van Woerden ◽  
H B Beverloo ◽  
A J P Veerman ◽  
B M Camitta ◽  
A H Loonen ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Resistance Profile ◽  
Drug Resistance Profile ◽  
Infant Acute Lymphoblastic Leukemia

scholarly journals Bacteria drug resistance profile affects knee and hip periprosthetic joint infection outcome with debridement, antibiotics and implant retention

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Bruno Alves Rudelli ◽  
Pedro Nogueira Giglio ◽  
Vladimir Cordeiro de Carvalho ◽  
José Ricardo Pécora ◽  
Henrique Melo Campos Gurgel ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Resistance Profile ◽  
Drug Resistance Profile ◽  
Implant Retention

Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting

AIDS ◽  
1999 ◽  
Vol 13 (14) ◽  
pp. 1863-1871 ◽  
Author(s):  
P. Richard Harrigan ◽  
Kurt Hertogs ◽  
Werner Verbiest ◽  
Rudi Pauwels ◽  
Brendan Larder ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Protease Inhibitor ◽  
Community Setting ◽  
Inhibitor Therapy ◽  
Protease Inhibitor Therapy ◽  
Hiv Drug Resistance ◽  
Resistance Profile ◽  
Drug Resistance Profile
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