scholarly journals Pathogenic, Phylogenetic, and Serological Analysis of Group I Fowl Adenovirus Serotype 4 SDSX Isolated From Shandong, China

2018 ◽  
Vol 9 ◽  
Author(s):  
Guanliu Yu ◽  
Yawen Wang ◽  
Minmin Zhang ◽  
Yun Lin ◽  
Yi Tang ◽  
...  
Keyword(s):  
Serological Analysis ◽  
Adenovirus Serotype ◽  
Fowl Adenovirus ◽  
Group I ◽  
Fowl Adenovirus Serotype 4

Pathogenicity and virus shedding ability of fowl adenovirus serotype 4 to ducks

2021 ◽  
pp. 109302
Author(s):  
Zhihui Tang ◽  
Meng Liu ◽  
Zhangshan Gao ◽  
Mengcong Li ◽  
Jie Cao ◽  
...  
Keyword(s):  
Adenovirus Serotype ◽  
Virus Shedding ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

Characterization of fowl adenovirus serotype 4 circulating in chickens in China

2019 ◽  
Vol 238 ◽  
pp. 108427 ◽  
Author(s):  
Zhimin Jiang ◽  
Mengda Liu ◽  
Chenxi Wang ◽  
Xiaowei Zhou ◽  
Fangtao Li ◽  
...  
Keyword(s):  
Adenovirus Serotype ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

scholarly journals Transcriptome Analysis Reveals New Insight of Fowl Adenovirus Serotype 4 Infection

2020 ◽  
Vol 11 ◽  
Author(s):  
Yuan Chen ◽  
Ruiling Huang ◽  
Guishu Qu ◽  
Yaoshun Peng ◽  
Lihui Xu ◽  
...  
Keyword(s):  
Transcriptome Analysis ◽  
Adenovirus Serotype ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

scholarly journals Experimental co-infection of variant infectious bursal disease virus and fowl adenovirus serotype 4 increases mortality and reduces immune response in chickens

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
A-hui Xu ◽  
Lu Sun ◽  
Kai-hang Tu ◽  
Qing-yuan Teng ◽  
Jia Xue ◽  
...  
Keyword(s):  
Immune Response ◽  
Disease Virus ◽  
Infectious Bursal Disease Virus ◽  
Clinical Symptoms ◽  
Interaction Mechanism ◽  
Infectious Bursal Disease ◽  
Adenovirus Serotype ◽  
Fowl Adenovirus ◽  
Bursal Disease ◽  
Fowl Adenovirus Serotype 4

AbstractInfectious bursal disease virus (IBDV) and fowl adenovirus serotype 4 (FAdV-4) cause infectious bursal disease (IBD) and hydropericardium-hepatitis syndrome, respectively. Recently, studies have reported co-infections of poultry with IBDV and FAdV-4, which is an important problem in the poultry industry. Here, the variant IBDV strain ZD-2018-1 and FAdV-4 isolate HB1501 were used to assess the pathogenicity of co-infection in 1-day-old specific pathogen-free (SPF) chickens. Compared with chickens infected with only FAdV-4, those coinfected with IBDV and FAdV-4 showed enhanced clinical symptoms, higher mortality, more severe tissue lesions, and higher biochemical index levels. Furthermore, the expression of interleukin (IL)-6, IL-1β, and interferon-γ mRNAs in the IBDV-FAdV-4 coinfected chickens was delayed, and the antibody response levels were significantly lower in those birds compared with the FAdV-4-infected chickens. These results indicate that co-infection with variant IBDV ZD-2018-1 and FAdV-4 HB1501 could significantly promote the pathogenicity of FAdV-4 and reduce the immune response in chickens. This study provides the foundation for further investigation of the interaction mechanism in IBDV and FAdV-4 co-infection.

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