scholarly journals Comparative Genomic and Phenotypic Analysis of the Vaginal Probiotic Lactobacillus rhamnosus GR-1

2018 ◽  
Vol 9 ◽  
Author(s):  
Mariya I. Petrova ◽  
Jean M. Macklaim ◽  
Sander Wuyts ◽  
Tine Verhoeven ◽  
Jos Vanderleyden ◽  
...  
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Comparative Genomic ◽  
Phenotypic Analysis ◽  
Probiotic Lactobacillus

scholarly journals Comparative Genomic and Functional Analysis of Lactobacillus casei and Lactobacillus rhamnosus Strains Marketed as Probiotics

2013 ◽  
Vol 79 (6) ◽  
pp. 1923-1933 ◽  
Author(s):  
François P. Douillard ◽  
Angela Ribbera ◽  
Hanna M. Järvinen ◽  
Ravi Kant ◽  
Taija E. Pietilä ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Transcription Initiation ◽  
Lactobacillus Rhamnosus ◽  
Comparative Genomic ◽  
Phenotypic Analysis ◽  
Carbohydrate Utilization ◽  
Content Type ◽  
Host Signaling ◽  
Toll Like Receptor 2 ◽  
Genome Content

ABSTRACTFourLactobacillusstrains were isolated from marketed probiotic products, includingL. rhamnosusstrains from Vifit (Friesland Campina) and Idoform (Ferrosan) andL. caseistrains from Actimel (Danone) and Yakult (Yakult Honsa Co.). Their genomes and phenotypes were characterized and compared in detail withL. caseistrain BL23 andL. rhamnosusstrain GG. Phenotypic analysis of the new isolates indicated differences in carbohydrate utilization betweenL. caseiandL. rhamnosusstrains, which could be linked to their genotypes. The two isolatedL. rhamnosusstrains had genomes that were virtually identical to that ofL. rhamnosusGG, testifying to their genomic stability and integrity in food products. TheL. caseistrains showed much greater genomic heterogeneity. Remarkably, all strains contained an intactspaCBApilus gene cluster. However, only theL. rhamnosusstrains produced mucus-binding SpaCBA pili under the conditions tested. Transcription initiation mapping demonstrated that the insertion of aniso-IS30element upstream of the pilus gene cluster inL. rhamnosusstrains but absent inL. caseistrains had constituted a functional promoter driving pilus gene expression. AllL. rhamnosusstrains triggered an NF-κB response via Toll-like receptor 2 (TLR2) in a reporter cell line, whereas theL. caseistrains did not or did so to a much lesser extent. This study demonstrates that the twoL. rhamnosusstrains isolated from probiotic products are virtually identical toL. rhamnosusGG and further highlights the differences between these andL. caseistrains widely marketed as probiotics, in terms of genome content, mucus-binding and metabolic capacities, and host signaling capabilities.

Probiotic Lactobacillus rhamnosus modulates the impacts of perfluorobutanesulfonate on oocyte developmental rhythm of zebrafish

2021 ◽  
Vol 776 ◽  
pp. 145975
Author(s):  
Chenyan Hu ◽  
Mengyuan Liu ◽  
Lizhu Tang ◽  
Baili Sun ◽  
Zileng Huang ◽  
...  
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Probiotic Lactobacillus

scholarly journals Effect of probiotic Lactobacillus rhamnosus GG intervention on global serum lipidomic profiles in healthy adults

2008 ◽  
Vol 14 (20) ◽  
pp. 3188 ◽  
Author(s):  
Riina A Kekkonen ◽  
Marko Sysi-Aho ◽  
Tuulikki Seppänen-Laakso ◽  
Ilkka Julkunen ◽  
Heikki Vapaatalo ◽  
...  
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Healthy Adults ◽  
Lactobacillus Rhamnosus Gg ◽  
Probiotic Lactobacillus

scholarly journals Genome Sequences of Potential Probiotic Lactobacillus rhamnosus Isolates from Human Infants

2017 ◽  
Vol 5 (14) ◽  
Author(s):  
Jason W. Arnold ◽  
Andrea Monteagudo-Mera ◽  
Eric Altermann ◽  
Maria Belen Cadenas ◽  
Amanda L. Thompson ◽  
...  
Keyword(s):  
Immune Response ◽  
Draft Genome ◽  
Lactobacillus Rhamnosus ◽  
Epithelial Barrier ◽  
Genome Sequences ◽  
Human Infants ◽  
Healthy Human ◽  
Content Type ◽  
Probiotic Potential ◽  
Probiotic Lactobacillus

ABSTRACT Probiotics provide health benefits to their hosts, including modulation of host immune response, inhibition of colonization by pathogens, modulation of the gut microbiota, and epithelial barrier enhancement. Here, we present the draft genome sequences of two newly isolated Lactobacillus rhamnosus strains of probiotic potential from healthy human infants.

Regulation of the Hepatic Antioxidant Response by the Probiotic Lactobacillus rhamnosus GG

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Bejan Jon Saeedi ◽  
Brian S Robinson ◽  
Joshua Owens ◽  
Ken Liu ◽  
Richard Eboka ◽  
...  
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Antioxidant Response ◽  
Lactobacillus Rhamnosus Gg ◽  
Probiotic Lactobacillus
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