scholarly journals Genetic Basis and Clonal Population Structure of Antibiotic Resistance in Campylobacter jejuni Isolated From Broiler Carcasses in Belgium

2018 ◽  
Vol 9 ◽  
Author(s):  
Mohamed Elhadidy ◽  
William G. Miller ◽  
Hector Arguello ◽  
Avelino Álvarez-Ordóñez ◽  
Alexandra Duarte ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Population Structure ◽  
Campylobacter Jejuni ◽  
Genetic Basis ◽  
Clonal Population ◽  
Clonal Population Structure

scholarly journals "Clonal" population structure of the malaria agent Plasmodium falciparum in high-infection regions

2005 ◽  
Vol 102 (48) ◽  
pp. 17388-17393 ◽  
Author(s):  
F. G. Razakandrainibe ◽  
P. Durand ◽  
J. C. Koella ◽  
T. De Meeus ◽  
F. Rousset ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Population Structure ◽  
Clonal Population ◽  
High Infection ◽  
Clonal Population Structure

scholarly journals PyClone: statistical inference of clonal population structure in cancer

2014 ◽  
Vol 11 (4) ◽  
pp. 396-398 ◽  
Author(s):  
Andrew Roth ◽  
Jaswinder Khattra ◽  
Damian Yap ◽  
Adrian Wan ◽  
Emma Laks ◽  
...  
Keyword(s):  
Population Structure ◽  
Statistical Inference ◽  
Clonal Population ◽  
Clonal Population Structure

scholarly journals Clonal population structure of encapsulated Haemophilus influenzae.

1988 ◽  
Vol 56 (8) ◽  
pp. 1837-1845 ◽  
Author(s):  
J M Musser ◽  
J S Kroll ◽  
E R Moxon ◽  
R K Selander
Keyword(s):  
Population Structure ◽  
Haemophilus Influenzae ◽  
Clonal Population ◽  
Clonal Population Structure

Trypanosoma vivax displays a clonal population structure

2009 ◽  
Vol 39 (13) ◽  
pp. 1475-1483 ◽  
Author(s):  
Craig W. Duffy ◽  
Liam J. Morrison ◽  
Alana Black ◽  
Gina L. Pinchbeck ◽  
Robert M. Christley ◽  
...  
Keyword(s):  
Population Structure ◽  
Trypanosoma Vivax ◽  
Clonal Population ◽  
Clonal Population Structure

The clonal population structure and serosubtypes of Neisseria meningitidis serogroup A isolated in China

1991 ◽  
pp. 159-164
Author(s):  
Li Xinwu ◽  
Hu Xujing ◽  
Gao Lihui ◽  
Xi Wenlong ◽  
Ji Yinduo ◽  
...  
Keyword(s):  
Population Structure ◽  
Neisseria Meningitidis ◽  
Clonal Population ◽  
Clonal Population Structure

scholarly journals Clonal Population Structure and Specific Genotypes of Multidrug-Resistant Campylobacter coli from Turkeys

2007 ◽  
Vol 73 (7) ◽  
pp. 2156-2164 ◽  
Author(s):  
C. B. D'lima ◽  
W. G. Miller ◽  
R. E. Mandrell ◽  
S. L. Wright ◽  
R. M. Siletzky ◽  
...  
Keyword(s):  
North Carolina ◽  
Population Structure ◽  
Multidrug Resistant ◽  
Source Tracking ◽  
Campylobacter Coli ◽  
Clonal Population ◽  
Antimicrobial Resistance Profile ◽  
Clonal Population Structure ◽  
Commercial Turkey ◽  
Sequence Types

ABSTRACT Commercial turkey flocks in North Carolina have been found to be colonized frequently with Campylobacter coli strains that are resistant to several antimicrobials (tetracycline, streptomycin, erythromycin, kanamycin, and ciprofloxacin/nalidixic acid). Such strains have been designated multidrug resistant (MDR). However, the population structure of MDR C. coli from turkeys remains poorly characterized. In this study, an analysis of multilocus sequence typing (MLST)-based sequence types (STs) of 59 MDR strains from turkeys revealed that the majority of these strains corresponded to one of 14 different STs, with three STs accounting for 41 (69%) of the strains. The major STs were turkey specific, and most (87%) of the strains with these STs were resistant to the entire panel of antibiotics mentioned above. Some (13%) of the strains with these STs were susceptible to just one or two of the antibiotics in this panel. Further subtyping using fla typing and pulsed-field gel electrophoresis with SmaI and KpnI revealed that the major MDR STs corresponded to strains of related but distinct subtypes, providing evidence for genomic diversification within these STs. These findings suggest that MDR strains of C. coli from turkeys have a clonal population structure characterized by the presence of a relatively small number of clonal groups that appear to be disseminated in the turkey production system. In addition, the observed correlation between STs and the MDR profiles of the microbes indicates that MLST-based typing holds potential for source-tracking applications specific to the animal source (turkeys) and the antimicrobial resistance profile (MDR status) of C. coli.

scholarly journals Clonal Population Structure and Antimicrobial Resistance of Campylobacter jejuni in Chicken Meat from Belgium

2009 ◽  
Vol 75 (13) ◽  
pp. 4264-4272 ◽  
Author(s):  
Ihab Habib ◽  
William G. Miller ◽  
Mieke Uyttendaele ◽  
Kurt Houf ◽  
Lieven De Zutter
Keyword(s):  
Campylobacter Jejuni ◽  
Molecular Typing ◽  
Gel Electrophoresis ◽  
Clonal Complex ◽  
Genotypic Diversity ◽  
Pulsed Field Gel Electrophoresis ◽  
Chicken Meat ◽  
Clonal Population ◽  
Clonal Population Structure ◽  
Sequence Types

ABSTRACT Campylobacter jejuni is one of the most important causes of human diarrhea worldwide. In the present work, multilocus sequence typing was used to study the genotypic diversity of 145 C. jejuni isolates from 135 chicken meat preparations sampled across Belgium. Isolates were further typed by pulsed-field gel electrophoresis, and their susceptibilities to six antimicrobials were determined. Fifty-seven sequence types (STs) were identified; 26.8% of the total typed isolates were ST-50, ST-45, or ST-257, belonging to clonal complex CC-21, CC-45, or CC-257, respectively. One clonal group comprised 22% (32/145) of all isolates, originating from five different companies and isolated over seven sampling months. Additionally, 53.1% of C. jejuni isolates were resistant to ciprofloxacin, and 48.2% were resistant to tetracycline; 28.9% (42/145) of all isolates were resistant to both ciprofloxacin and tetracycline. The correlation between certain C. jejuni clonal groups and resistance to ciprofloxacin and tetracycline was notable. C. jejuni isolates assigned to CC-21 (n = 35) were frequently resistant to ciprofloxacin (65.7%) and tetracycline (40%); however, 90% (18/20) of the isolates assigned to CC-45 were pansusceptible. The present study demonstrates that certain C. jejuni genotypes recur frequently in the chicken meat supply. The results of molecular typing, combined with data on sample sources, indicate a possible dissemination of C. jejuni clones with high resistance to ciprofloxacin and/or tetracycline. Whether certain clonal groups are common in the environment and repeatedly infect Belgian broiler flocks or whether they have the potential to persist on farms or in slaughterhouses needs further investigation.

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