scholarly journals Characterization of Asymptomatic Bacteriuria Escherichia coli Isolates in Search of Alternative Strains for Efficient Bacterial Interference against Uropathogens

2018 ◽  
Vol 9 ◽  
Author(s):  
Christoph Stork ◽  
Beáta Kovács ◽  
Barnabás Rózsai ◽  
Johannes Putze ◽  
Matthias Kiel ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Asymptomatic Bacteriuria ◽  
Bacterial Interference

scholarly journals Molecular Characterization of Uropathogenic Escherichia coli Reveals Emergence of Drug Resistant O15, O22 and O25 Serogroups

Medicina ◽  
2019 ◽  
Vol 55 (11) ◽  
pp. 733 ◽  
Author(s):  
Ruta Prakapaite ◽  
Frederic Saab ◽  
Rita Planciuniene ◽  
Vidmantas Petraitis ◽  
Thomas J. Walsh ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Asymptomatic Bacteriuria ◽  
Empirical Therapy ◽  
Uropathogenic Escherichia Coli ◽  
Phylogenetic Groups ◽  
E Coli ◽  
Tract Infections ◽  
Resistance Rates

Background and Objectives: Uropathogenic Escherichia coli (UPEC) are common pathogens causing urinary tract infections (UTIs). We aimed to investigate the relationship among clinical manifestation, serogroups, phylogenetic groups, and antimicrobial resistance among UPEC. Materials and Methods: One-hundred Escherichia coli isolates recovered from urine and ureteral scrapings were used for the study. The prevalence of antimicrobial resistance was determined by using European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendations. E. coli serogroups associated with UTI, as well as phylogenetic diversity were analyzed using multiplex PCR reactions. Results: Eighty-seven strains (87%) were isolated from females, while 13 (13%) from males. A high frequency of resistance to cephalosporins (43%) and fluoroquinolones (31%) was observed. Among UTI-associated serogroups O15 (32.8%), O22 (23.4%), and O25 (15.6%) were dominant and demonstrated elevated resistance rates. The E. coli phylogenetic group B2 was most common. These observations extended to pregnant patients with asymptomatic bacteriuria. Conclusions: Due to high rates of resistance, strategies using empirical therapy of second-generation cephalosporins and fluoroquinolones should be reconsidered in this population.

scholarly journals Molecular Characterization of the Escherichia coli Asymptomatic Bacteriuria Strain 83972: the Taming of a Pathogen

2006 ◽  
Vol 74 (1) ◽  
pp. 781-785 ◽  
Author(s):  
Per Klemm ◽  
Viktoria Roos ◽  
Glen C. Ulett ◽  
Catharina Svanborg ◽  
Mark A. Schembri
Keyword(s):  
Escherichia Coli ◽  
Immune Response ◽  
Urinary Bladder ◽  
Molecular Characterization ◽  
Asymptomatic Bacteriuria ◽  
Human Urinary Bladder ◽  
Genes Encoding

ABSTRACT Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.

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