scholarly journals Characterization of Enterococcus Isolates Colonizing the Intestinal Tract of Intensive Care Unit Patients Receiving Selective Digestive Decontamination

2017 ◽  
Vol 8 ◽  
Author(s):  
Teresita d. J. Bello Gonzalez ◽  
Phu Pham ◽  
Janetta Top ◽  
Rob J. L. Willems ◽  
Willem van Schaik ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Intestinal Tract ◽  
Selective Digestive Decontamination

Selective digestive decontamination by erythromycin-base in a polyvalent intensive care unit

1993 ◽  
Vol 19 (4) ◽  
pp. 191-196 ◽  
Author(s):  
C. L. de Champs ◽  
D. P. Guelon ◽  
R. M. Garnier ◽  
M. C. Poupart ◽  
O. Y. Mansoor ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Selective Digestive Decontamination ◽  
Erythromycin Base

scholarly journals EVALUATION OF ANTIBIOTIC TREATMENT AND ANTIBIOTIC DE-ESCALATION IN A INTENSIVE CARE UNIT WITH SELECTIVE DIGESTIVE DECONTAMINATION

2015 ◽  
Vol 3 (Suppl 1) ◽  
pp. A2
Author(s):  
C Sánchez Ramirez ◽  
L Caipe Balcázar ◽  
S Hípola Escalada ◽  
MA Hernández Viera ◽  
M Cabrera Santana ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Antibiotic Treatment ◽  
Selective Digestive Decontamination

scholarly journals Characterization of Dexmedetomidine Dosing and Safety in Neonates and Infants

2015 ◽  
Vol 20 (2) ◽  
pp. 112-118 ◽  
Author(s):  
Lauren M. Estkowski ◽  
Jennifer L. Morris ◽  
Elizabeth A. Sinclair
Keyword(s):  
Blood Pressure ◽  
Intensive Care Unit ◽  
Heart Rate ◽  
Intensive Care ◽  
Systolic Blood Pressure ◽  
Vital Signs ◽  
Pediatric Intensive Care ◽  
Neonates And Infants ◽  
To Receive

OBJECTIVES: To describe and compare off-label use and cardiovascular (CV) adverse effects of dexmedetomidine in neonates and infants in the pediatric intensive care unit (PICU). METHODS: Patients younger than 12 months with corrected gestational ages of at least 37 weeks who were receiving continuous infusion of dexmedetomidine at a tertiary pediatric referral center between October 2007 and August 2012 were assessed retrospectively. Patients were excluded if dexmedetomidine was used for procedural sedation, postoperative CV surgery, or if postanesthesia infusion weaning orders existed at the time of PICU admission. RESULTS: The median minimum dexmedetomidine dose was similar between infants and neonates at 0.2 mcg/kg/hr (IQR, 0.17–0.3) versus 0.29 mcg/kg/hr (IQR, 0.2–0.31), p = 0.35. The median maximum dose was higher for infants than neonates (0.6 mcg/kg/hr [IQR, 0.4–0.8] vs. 0.4 mcg/kg/hr [IQR, 0.26–0.6], p < 0.01). Additional sedative use was more common in infants than neonates (75/99 [76%] vs. 15/28 [54%], p = 0.02). At least 1 episode of hypotension was noted in 34/127 (27%) patients and was similar between groups. An episode of bradycardia was identified more frequently in infants than neonates (55/99 [56%] vs. 2/28 [7%], p < 0.01). Significant reduction in heart rate and systolic blood pressure was noted when comparing baseline vital signs to lowest heart rate and systolic blood pressure during infusion (p < 0.01). CONCLUSIONS: Dexmedetomidine dose ranges were similar to US Food and Drug Administration–labeled dosages for intensive care unit sedation in adults. More infants than neonates experienced a bradycardia episode, but infants were also more likely to receive higher dosages of dexmedetomidine and additional sedatives.

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