scholarly journals Elucidation of the Role of 3-Hydroxy Fatty Acids in Cryptococcus-amoeba Interactions

2017 ◽  
Vol 8 ◽  
Author(s):  
Uju L. Madu ◽  
Adepemi O. Ogundeji ◽  
Carolina H. Pohl ◽  
Jacobus Albertyn ◽  
Olihile M. Sebolai
Keyword(s):  
Fatty Acids ◽  
Hydroxy Fatty Acids

Cholesterol-cerebroside interaction: The role of α-hydroxy fatty acids

Lipids ◽  
1972 ◽  
Vol 7 (11) ◽  
pp. 733-737 ◽  
Author(s):  
Hubert S. Mickel ◽  
Penelope L. Hill
Keyword(s):  
Fatty Acids ◽  
Hydroxy Fatty Acids

Formation of prostanoids and hydroxy fatty acids by stimulated peritoneal mast cells: Role of the dietary fat type in rat

1993 ◽  
Vol 1167 (2) ◽  
pp. 147-154 ◽  
Author(s):  
Charles M.C.J. van Haaster ◽  
Wim Engels ◽  
Paul J.M.R. Lemmens ◽  
Gerard Hornstra ◽  
Ger J. van der Vusse
Keyword(s):  
Fatty Acids ◽  
Mast Cells ◽  
Dietary Fat ◽  
Hydroxy Fatty Acids ◽  
Peritoneal Mast Cells

scholarly journals Regiobiochemical analysis reveals the role of castor LPAT2 in the accumulation of hydroxy fatty acids in transgenic lesquerella seeds

2020 ◽  
Vol 25 ◽  
pp. 101617
Author(s):  
Grace Qianhong Chen ◽  
Jiann-Tsyh Lin ◽  
Harrie van Erp ◽  
Kumiko Johnson ◽  
Chaofu Lu
Keyword(s):  
Fatty Acids ◽  
Hydroxy Fatty Acids

The role of diacylglycerol acyltransferase-1 and phospholipid:diacylglycerol acyltransferase-1 and -2 in the incorporation of hydroxy fatty acids into triacylglycerol in Arabidopsis thaliana expressing a castor bean oleate 12-hydroxylase geneThis paper is one of a selection of papers published in a Special Issue from the National Research Council of Canada – Plant Biotechnology Institute.

Botany ◽  
2009 ◽  
Vol 87 (6) ◽  
pp. 552-560 ◽  
Author(s):  
Melanie Dauk ◽  
Patricia Lam ◽  
Mark A. Smith
Keyword(s):  
Fatty Acids ◽  
Neutral Lipids ◽  
National Research Council ◽  
Plant Biotechnology ◽  
Hydroxy Fatty Acids ◽  
Acyltransferase Activity ◽  
Unusual Fatty Acids ◽  
Arabidopsis Mutant ◽  
Mutant Lines

Expression of oleate 12-hydroxylase genes in Arabidopsis results in the accumulation of hydroxy fatty acids in seed triacylglycerol (TAG). The pathways by which these unusual fatty acids become incorporated into TAG are not well understood. We expressed a fatty acid hydroxylase cDNA in Arabidopsis mutant lines to assess the role of three enzymes implicated in TAG assembly in this species. Plants deficient in the expression of phospholipid:diacylglycerol acyltransferase-1 or -2 accumulated hydroxy fatty acids and showed no differences to equivalent transformed wild-type plants. Plants lacking diacylglylcerol acyltransferase activity were also able to accumulate hydroxy fatty acids in seed neutral lipids. Triacylglycerol species containing one and two hydroxy fatty acids were abundant, and small amounts of trihydroxy-TAG were detected. These results indicate that individually, the three enzymes do not play a major role in the incorporation of hydroxy fatty acids into TAG.

scholarly journals The Evaluation of the Role of Beta-Hydroxy Fatty Acids on Chronic Inflammation and Insulin Resistance

2006 ◽  
Vol 2006 ◽  
pp. 1-6 ◽  
Author(s):  
A. S. Soydan ◽  
H. S. Dokmetas ◽  
M. Cetin ◽  
A. Koyuncu ◽  
E. Kaptanoglu ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Lipid A ◽  
Culture Media ◽  
Inflammatory Diseases ◽  
Venous Blood ◽  
Hydroxy Fatty Acids ◽  
Sterile Inflammation ◽  
Chronic Inflammatory Diseases

β-hydroxy fatty acids are a major component of lipid A moiety of lipopolysaccaride. We aimed to investigate the role of freeβ-hydroxy fatty acids on inflammation, as well as to evaluate their effects on cytokine release from human blood cells, and whether they exist in plasma of patients with chronic inflammatory diseases with/without insulin resistance. Peripheral venous blood was incubated withβ-hydroxy lauric andβ-hydroxy myristic acids (each 100 ng, 1μg, 10μg/mL) up to 24 hours. Cytokines were measured from culture media and plasma. Free fatty acids and biochemical parameters were also measured from patients' plasma. Onlyβ-hydroxy lauric acid significantly stimulated interleukin-6 production at 10μg/mL compared to control (533.9±218.1versus438.3±219.6pg/mL,P<.05). However, freeβ-hydroxy lauric and myristic acids were not found in patients' plasma. Therefore, freeβ-hydroxy lauric and myristic acids do not seem to have a role on sterile inflammation in chronic inflammatory diseases associated with insulin resistance.

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