scholarly journals Multidrug- and Extensively Drug-Resistant Uropathogenic Escherichia coli Clinical Strains: Phylogenetic Groups Widely Associated with Integrons Maintain High Genetic Diversity

2016 ◽  
Vol 7 ◽  
Author(s):  
Sara A. Ochoa ◽  
Ariadnna Cruz-Córdova ◽  
Victor M. Luna-Pineda ◽  
Juan P. Reyes-Grajeda ◽  
Vicenta Cázares-Domínguez ◽  
...  
2021 ◽  
Vol 10 (38) ◽  
Author(s):  
Naveen Chaudhary ◽  
Dharminder Singh ◽  
Chandradeo Narayan ◽  
Bhaskar Samui ◽  
Balvinder Mohan ◽  
...  

Escherichia phage 590B, which was isolated from community sewage water in Chandigarh, India, exhibited lytic activity against an extensively drug-resistant uropathogenic Escherichia coli isolate. The genome of the phage is linear, double-stranded, and 44.39 kb long. Phage 590B is a member of the Siphoviridae family and is closest to phage vB_EcoS_XY2, which was isolated in China.


2016 ◽  
Vol 6 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Ihsan Ali ◽  
Zara Rafaque ◽  
Safia Ahmed ◽  
Sajid Malik ◽  
Javid Iqbal Dasti

2018 ◽  
Vol 38 (1) ◽  
pp. 79-87 ◽  
Author(s):  
Maria G. Spindola ◽  
Marcos P. V. Cunha ◽  
Luisa Z. Moreno ◽  
Cristina R. Amigo ◽  
Ana P. S. Silva ◽  
...  

2019 ◽  
Vol 39 (5) ◽  
Author(s):  
Ruolan Bai ◽  
Shuijing Chi ◽  
Xiaofei Li ◽  
Xiting Dai ◽  
Zhenhua Ji ◽  
...  

AbstractTuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) which has been threatening global public health for many years. High genetic diversity is dominant feature of Mtb. Increasing cases of multidrug-resistant (MDR) tuberculosis (MDR-TB) is a serious public health problem to TB control in China. Spontaneous mutations in the Mtb genome can alter proteins which are the target of drugs, making the bacteria drug resistant. The purpose of the present study was to analyze the genotype of Mtb isolates from some areas in Yunnan, China and explore the association between genotypes and MDR-TB. Using spoligotyping, we identified Beijing genotypes, six non-Beijing genotypes and a number of orphan genotypes from 270 Mtb isolates from patients in Yunnan Province during 2014–2016. Of 270 Mtb isolates, 102 clinical Mtb strains were identified as drug-resistant (DR) by drug susceptibility testing (DST), among them, 52 MDR strains. Beijing genotypes occupied the highest MDR proportion (78.85%) followed by the orphan genotypes (15.38%). The characteristics of MDR strains showed high genetic diversity. The results will help to efficiently improve diagnosis and treatment and provide valuable information for Mtb molecular epidemiology.


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