scholarly journals Impact of oxidative stress defense on bacterial survival and morphological change in Campylobacter jejuni under aerobic conditions

2015 ◽  
Vol 6 ◽  
Author(s):  
Euna Oh ◽  
Lynn McMullen ◽  
Byeonghwa Jeon
Keyword(s):  
Oxidative Stress ◽  
Morphological Change ◽  
Campylobacter Jejuni ◽  
Bacterial Survival ◽  
Aerobic Conditions ◽  
Oxidative Stress Defense ◽  
Stress Defense

scholarly journals CosR Regulation of perR Transcription for the Control of Oxidative Stress Defense in Campylobacter jejuni

2021 ◽  
Vol 9 (6) ◽  
pp. 1281
Author(s):  
Myungseo Park ◽  
Sunyoung Hwang ◽  
Sangryeol Ryu ◽  
Byeonghwa Jeon
Keyword(s):  
Oxidative Stress ◽  
Campylobacter Jejuni ◽  
Response Regulator ◽  
Iron Chelator ◽  
Mobility Shift ◽  
Oxidative Stress Defense ◽  
Dnase I Footprinting ◽  
Oxygen Sensitive ◽  
Mobility Shift Assay ◽  
Stress Defense

Oxidative stress resistance is an important mechanism to sustain the viability of oxygen-sensitive microaerophilic Campylobacter jejuni. In C. jejuni, gene expression associated with oxidative stress defense is modulated by PerR (peroxide response regulator) and CosR (Campylobacter oxidative stress regulator). Iron also plays an important role in the regulation of oxidative stress, as high iron concentrations reduce the transcription of perR. However, little is known about how iron affects the transcription of cosR. The level of cosR transcription was increased when the defined media MEMα (Minimum Essential Medium) was supplemented with ferrous (Fe²⁺) and ferric (Fe3⁺) iron and the Mueller–Hinton (MH) media was treated with an iron chelator, indicating that iron upregulates cosR transcription. However, other divalent cationic ions, such as Zn2+, Cu2+, Co2+, and Mn2+, did not affect cosR transcription, suggesting that cosR transcription is regulated specifically by iron. Interestingly, the level of perR transcription was increased when CosR was overexpressed. The positive regulation of perR transcription by CosR was observed both in the presence or in the absence of iron. The results of the electrophoretic mobility shift assay showed that CosR directly binds to the perR promoter. DNase I footprinting assays revealed that the CosR binding site in the perR promoter overlaps with the PerR box. In the study, we demonstrated that cosR transcription is increased in iron-rich conditions, and CosR positively regulates the transcription of PerR, another important regulator of oxidative stress defense in C. jejuni. These results provide new insight into how C. jejuni regulates oxidative stress defense by coordinating the transcription of perR and cosR in response to iron.

scholarly journals Fur controls iron homeostasis and oxidative stress defense in the oligotrophic alpha-proteobacterium Caulobacter crescentus

2009 ◽  
Vol 37 (14) ◽  
pp. 4812-4825 ◽  
Author(s):  
José F. da Silva Neto ◽  
Vânia S. Braz ◽  
Valéria C. S. Italiani ◽  
Marilis V. Marques
Keyword(s):  
Oxidative Stress ◽  
Iron Homeostasis ◽  
Caulobacter Crescentus ◽  
Oxidative Stress Defense ◽  
And Oxidative Stress ◽  
Stress Defense

A proteomics view on the role of drought-induced senescence and oxidative stress defense in enhanced stem reserves remobilization in wheat

2011 ◽  
Vol 74 (10) ◽  
pp. 1959-1973 ◽  
Author(s):  
Mitra Mohammadi Bazargani ◽  
Elham Sarhadi ◽  
Ali-Akbar Shahnejat Bushehri ◽  
Andrea Matros ◽  
Hans-Peter Mock ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Stress Defense ◽  
Stem Reserves ◽  
And Oxidative Stress ◽  
Stress Defense

scholarly journals Catalase Takes Part in Rat Liver Mitochondria Oxidative Stress Defense

2007 ◽  
Vol 282 (33) ◽  
pp. 24407-24415 ◽  
Author(s):  
Mauro Salvi ◽  
Valentina Battaglia ◽  
Anna Maria Brunati ◽  
Nicoletta La Rocca ◽  
Elena Tibaldi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Oxidative Stress Defense ◽  
Stress Defense

OXIDATIVE STRESS, DEFENSE RESPONSE, AND EARLY BIOMARKERS FOR LEAD-CONTAMINATED SOIL IN VICIA FABA SEEDLINGS

2008 ◽  
Vol 27 (4) ◽  
pp. 970 ◽  
Author(s):  
Cheng-Run Wang ◽  
Xiao-Rong Wang ◽  
Yuan Tian ◽  
Hong-Xia Yu ◽  
Xue-Yuan Gu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vicia Faba ◽  
Contaminated Soil ◽  
Defense Response ◽  
Early Biomarkers ◽  
Oxidative Stress Defense ◽  
Stress Defense
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