scholarly journals Far from being well understood: multiple protein phosphorylation events control cell differentiation in Bacillus subtilis at different levels

2014 ◽  
Vol 5 ◽  
Author(s):  
Jan Gerwig ◽  
Jörg Stülke
Keyword(s):  
Bacillus Subtilis ◽  
Cell Differentiation ◽  
Protein Phosphorylation ◽  
Control Cell ◽  
Multiple Protein ◽  
Different Levels ◽  
Control Cell Differentiation

scholarly journals The histone subcode: poly(ADP‐ribose) polymerase‐1 (Parp‐1) and Parp‐2 control cell differentiation by regulating the transcriptional intermediary factor TIF1β and the heterochromatin protein HPlα

2008 ◽  
Vol 22 (11) ◽  
pp. 3853-3865 ◽  
Author(s):  
Delphine Quénet ◽  
Véronique Gasser ◽  
Laetitia Fouillen ◽  
Florence Cammas ◽  
Sarah Sanglier‐Cianferani ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Control Cell ◽  
Heterochromatin Protein ◽  
Parp 1 ◽  
Control Cell Differentiation

scholarly journals Copper mediates auxin signalling to control cell differentiation in the copper moss Scopelophila cataractae

2014 ◽  
Vol 66 (5) ◽  
pp. 1205-1213 ◽  
Author(s):  
Toshihisa Nomura ◽  
Misao Itouga ◽  
Mikiko Kojima ◽  
Yukari Kato ◽  
Hitoshi Sakakibara ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Control Cell ◽  
Auxin Signalling ◽  
Copper Moss ◽  
Control Cell Differentiation

scholarly journals Wild-Type NRas and KRas Perform Distinct Functions during Transformation

2007 ◽  
Vol 27 (19) ◽  
pp. 6742-6755 ◽  
Author(s):  
Poppy P. Fotiadou ◽  
Chiaki Takahashi ◽  
Hasan N. Rajabi ◽  
Mark E. Ewen
Keyword(s):  
Signal Transduction ◽  
Cell Differentiation ◽  
Control Cell ◽  
Molecular Switches ◽  
Signal Transduction Pathways ◽  
Wild Type ◽  
Functional Specificity ◽  
Cellular Processes ◽  
Ras Isoforms ◽  
Control Cell Differentiation

ABSTRACT The ras proto-oncogenes, of which there are four isoforms, are molecular switches that function in signal transduction pathways to control cell differentiation, proliferation, and survival. How the Ras isoforms orchestrate cellular processes that affect behavior is poorly understood. Further, why cells express two or more Ras isoforms is unknown. Here, using a genetically defined system, we show that the presence of both wild-type KRas and NRas isoforms is required for transformation because they perform distinct nonoverlapping functions: wild-type NRas regulates adhesion, and KRas coordinates motility. Remarkably, we find that Ras isoforms achieve functional specificity by engaging different signaling pathways to affect the same cellular processes, thereby coordinating cellular outcome. Although we find that signaling from both isoforms intersects in actin and microtubule cytoskeletons, our results suggest that KRas signals through Akt and Cdc42 while NRas signals through Raf and RhoA. Our analyses suggest a previously unappreciated convergence of different Ras isoforms on the dynamics of the processes involved in transformation.

scholarly journals Sumoylation differentially regulates Sp1 to control cell differentiation

2014 ◽  
Vol 111 (15) ◽  
pp. 5574-5579 ◽  
Author(s):  
L. Gong ◽  
W.-K. Ji ◽  
X.-H. Hu ◽  
W.-F. Hu ◽  
X.-C. Tang ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Control Cell ◽  
Control Cell Differentiation

Photocontrolled chondrogenic differentiation and long-term tracking of mesenchymal stem cells in vivo by upconversion nanoparticles

2022 ◽  
Author(s):  
Zihan Yang ◽  
Xichao Wang ◽  
Guohai Liang ◽  
Anli Yang ◽  
Jinming Li
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cell Differentiation ◽  
Chondrogenic Differentiation ◽  
Control Cell ◽  
Upconversion Nanoparticles ◽  
Multiple Differentiation ◽  
Control Cell Differentiation

Mesenchymal stem cells (MSCs) have multiple differentiation potentials and its clinical application is limited with control cell differentiation and long-term tracing in vivo. Here, we developed a upconversion nanoparticle (UCNP)...

scholarly journals RGMB and neogenin control cell differentiation in the developing olfactory epithelium

Development ◽  
2016 ◽  
Vol 143 (9) ◽  
pp. 1534-1546 ◽  
Author(s):  
Joseph Wai Keung Kam ◽  
Emilie Dumontier ◽  
Christopher Baim ◽  
Alexandra C. Brignall ◽  
David Mendes da Silva ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Olfactory Epithelium ◽  
Control Cell ◽  
Control Cell Differentiation
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