scholarly journals Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties

2019 ◽  
Vol 10 ◽  
Author(s):  
Anastazja Andrzejewska ◽  
Rusan Catar ◽  
Janosch Schoon ◽  
Taimoor Hasan Qazi ◽  
Frauke Andrea Sass ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Functional Properties ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Parameter Analysis ◽  
Human Bone Marrow ◽  
Donor Age

Isolation Yield and Osteogenic Potential of Human Bone Marrow Stromal Cells are Maintained Irrespective of Age or Gender

2007 ◽  
Vol 361-363 ◽  
pp. 1149-1152
Author(s):  
Jeong Joon Yoo ◽  
Jeon Hyun Bang ◽  
Kyung Hoi Koo ◽  
Kang Sup Yoon ◽  
Hee Joong Kim
Keyword(s):  
Bone Marrow ◽  
Osteogenic Differentiation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Mononuclear Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Osteogenic Potential ◽  
Donor Age

The relationships between donor age and gender and initial isolation yield and the osteogenic potentials of human bone marrow stromal cells (hBMSCs) have not been clearly elucidated. The authors investigated whether isolation yields and the osteogenic differentiation potentials of hBMSCs are indeed dependent on donor age or gender. Fresh bone marrow was aspirated from iliac crest of 72 donors (mean age 54.1 years; range, 23-84 years; 39 men and 33 women) undergoing total hip arthroplasty. Numbers of mononuclear cells, numbers of colony forming unit-fibroblasts (CFU-Fs) and alkaline phosphatase (ALP)-positive CFU-Fs, and numbers of BMSCs after isolation culture were not found to be significantly dependent on donor age or gender. Moreover, no significant age- or gender-related differences were observed in terms of the proliferation activities, ALP activities, and calcium contents of BMSCs during in vitro osteogenic differentiation. The data obtained from 72 human donors revealed no significant age- or genderrelated differences among hBMSCs in terms of isolation yields, proliferation activities, and osteogenic potentials.

Bone Tissue-Engineered Implants Using Human Bone Marrow Stromal Cells: Effect of Culture Conditions and Donor Age

2002 ◽  
Vol 8 (6) ◽  
pp. 911-920 ◽  
Author(s):  
S.C. Mendes ◽  
J.M. Tibbe ◽  
M. Veenhof ◽  
K. Bakker ◽  
S. Both ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Tissue ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Culture Conditions ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Donor Age

Therapeutic Impact of Human Bone Marrow Stromal Cells Expanded by Animal Serum–Free Medium for Cerebral Infarct in Rats

Neurosurgery ◽  
2011 ◽  
Vol 68 (6) ◽  
pp. 1733-1742 ◽  
Author(s):  
Taku Sugiyama ◽  
Satoshi Kuroda ◽  
Yukari Takeda ◽  
Mitsufumi Nishio ◽  
Masaki Ito ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Serum Free Medium ◽  
Free Medium ◽  
Serum Free ◽  
Therapeutic Impact

scholarly journals Leptin Induces Apoptosis via ERK/cPLA2/CytochromecPathway in Human Bone Marrow Stromal Cells

2003 ◽  
Vol 278 (24) ◽  
pp. 21920-21929 ◽  
Author(s):  
Ghi Su Kim ◽  
Jeong Soo Hong ◽  
Seung Wook Kim ◽  
Jung-Min Koh ◽  
Chung Sun An ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow

scholarly journals Directed Differentiation of Human Bone Marrow Stromal Cells to Fate-Committed Schwann Cells

2017 ◽  
Vol 9 (4) ◽  
pp. 1097-1108 ◽  
Author(s):  
Sa Cai ◽  
Yat-Ping Tsui ◽  
Kin-Wai Tam ◽  
Graham Ka-Hon Shea ◽  
Richard Shek-Kwan Chang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Schwann Cells ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Directed Differentiation
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