scholarly journals Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells

2015 ◽  
Vol 6 ◽  
Author(s):  
Veronica J. Peschansky ◽  
Chiara Pastori ◽  
Zane Zeier ◽  
Dario Motti ◽  
Katya Wentzel ◽  
...  
Keyword(s):  
Gene Expression ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Altered Gene Expression ◽  
Non Coding Rna ◽  
Altered Gene ◽  
Long Non Coding Rna

scholarly journals Analysis of Gene Expression in Mouse Spinal Cord-derived Neural Precursor Cells During Neuronal Differentiation

2009 ◽  
Vol 7 (2) ◽  
pp. 85-96
Author(s):  
Joon-Ik Ahn ◽  
So-Young Kim ◽  
Moon-Jeong Ko ◽  
Hye-Joo Chung ◽  
Ho-Sang Jeong
Keyword(s):  
Gene Expression ◽  
Spinal Cord ◽  
Neuronal Differentiation ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Mouse Spinal Cord

Neural precursor cells from a fatal human motoneuron disease differentiate despite aberrant gene expression

2007 ◽  
Vol 67 (3) ◽  
pp. 270-284 ◽  
Author(s):  
Niklas Pakkasjärvi ◽  
Laura Kerosuo ◽  
Heidi Nousiainen ◽  
Massimiliano Gentile ◽  
Juha Saharinen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Motoneuron Disease ◽  
Aberrant Gene Expression ◽  
Aberrant Gene

Molecular and Microscopic Analysis of Altered Gene Expression in Transgenic and Gene Targeted Mice

1996 ◽  
Vol 54 ◽  
pp. 12-13
Author(s):  
W. K. Jones ◽  
J. Robbins
Keyword(s):  
Gene Expression ◽  
Pulmonary Veins ◽  
Microscopic Analysis ◽  
Mouse Tissue ◽  
Adult Heart ◽  
Heavy Chains ◽  
Altered Gene Expression ◽  
Altered Gene ◽  
Pulmonary Myocardium

Two myosin heavy chains (MyHC) are expressed in the mammalian heart and are differentially regulated during development. In the mouse, the α-MyHC is expressed constitutively in the atrium. At birth, the β-MyHC is downregulated and replaced by the α-MyHC, which is the sole cardiac MyHC isoform in the adult heart. We have employed transgenic and gene-targeting methodologies to study the regulation of cardiac MyHC gene expression and the functional and developmental consequences of altered α-MyHC expression in the mouse.We previously characterized an α-MyHC promoter capable of driving tissue-specific and developmentally correct expression of a CAT (chloramphenicol acetyltransferase) marker in the mouse. Tissue surveys detected a small amount of CAT activity in the lung (Fig. 1a). The results of in situ hybridization analyses indicated that the pattern of CAT transcript in the adult heart (Fig. 1b, top panel) is the same as that of α-MyHC (Fig. 1b, lower panel). The α-MyHC gene is expressed in a layer of cardiac muscle (pulmonary myocardium) associated with the pulmonary veins (Fig. 1c). These studies extend our understanding of α-MyHC expression and delimit a third cardiac compartment.

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