scholarly journals Cardioprotective Roles of Endothelial Progenitor Cell-Derived Exosomes

2021 ◽  
Vol 8 ◽  
Author(s):  
Cai-Yu Zeng ◽  
Jia Xu ◽  
Xin Liu ◽  
Yuan-Qiang Lu
Keyword(s):  
Nucleic Acids ◽  
Extracellular Vesicles ◽  
Intercellular Communication ◽  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Endothelial Progenitor ◽  
Pleiotropic Functions

Graphical AbstractEPC-EXs: The hallmarks and pleiotropic functions. EPC-EXs are extracellular vesicles generated by EPCs and they carry lipids, proteins, nucleic acids, metabolites, and some EPC markers. They mediate intercellular communication and affect various aspects of cell biology.

scholarly journals Pivotal Role of Lnk Adaptor Protein in Endothelial Progenitor Cell Biology for Vascular Regeneration

2009 ◽  
Vol 104 (8) ◽  
pp. 969-977 ◽  
Author(s):  
Sang-Mo Kwon ◽  
Takahiro Suzuki ◽  
Atsuhiko Kawamoto ◽  
Masaaki Ii ◽  
Masamichi Eguchi ◽  
...  
Keyword(s):  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Adaptor Protein ◽  
Pivotal Role ◽  
Endothelial Progenitor ◽  
Vascular Regeneration

scholarly journals Effects of androgens on endothelial progenitor cells in vitro and in vivo

2009 ◽  
Vol 117 (10) ◽  
pp. 355-364 ◽  
Author(s):  
Gian Paolo Fadini ◽  
Mattia Albiero ◽  
Andrea Cignarella ◽  
Chiara Bolego ◽  
Christian Pinna ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Adult Males ◽  
Endothelial Progenitor ◽  
Healthy Human

The beneficial or detrimental effects of androgens on the cardiovascular system are debated. Endothelial progenitor cells are bone-marrow-derived cells involved in endothelial healing and angiogenesis, which promote cardiovascular health. Oestrogens are potent stimulators of endothelial progenitor cells, and previous findings have indicated that androgens may improve the biology of these cells as well. In the present study, we show that testosterone and its active metabolite dihydrotestosterone exert no effects on the expansion and function of late endothelial progenitors isolated from the peripheral blood of healthy human adult males, whereas they positively modulate early ‘monocytic’ endothelial progenitor cells. In parallel, we show that castration in rats is followed by a decrease in circulating endothelial progenitor cells, but that testosterone and dihydrotestosterone replacement fails to restore endothelial progenitor cells towards normal levels. This is associated with persistently low oestrogen levels after androgen replacement in castrated rats. In a sample of 62 healthy middle-aged men, we show that circulating endothelial progenitor cell levels are more directly associated with oestradiol, rather than with testosterone, concentrations. In conclusion, our results collectively demonstrate that androgens exert no direct effects on endothelial progenitor cell biology in vitro and in vivo.

scholarly journals The effect of aspirin on endothelial progenitor cell biology: Preliminary investigation of novel properties

2010 ◽  
Vol 126 (3) ◽  
pp. e175-e179 ◽  
Author(s):  
Junyang Lou ◽  
Thomas J. Povsic ◽  
Jason D. Allen ◽  
Stacie D. Adams ◽  
Shelley Myles ◽  
...  
Keyword(s):  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Preliminary Investigation ◽  
Endothelial Progenitor

Current perspective of pathophysiological and interventional effects on endothelial progenitor cell biology: Focus on Pi3K/AKT/eNOS pathway

2010 ◽  
Vol 144 (3) ◽  
pp. 350-366 ◽  
Author(s):  
Bert R. Everaert ◽  
Emeline M. Van Craenenbroeck ◽  
Vicky Y. Hoymans ◽  
Steven E. Haine ◽  
Luc Van Nassauw ◽  
...  
Keyword(s):  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Endothelial Progenitor ◽  
Current Perspective

scholarly journals Endothelial progenitor cell biology in disease and tissue regeneration

2011 ◽  
Vol 4 (1) ◽  
pp. 24 ◽  
Author(s):  
Andrea L George ◽  
Pradeep Bangalore-Prakash ◽  
Shilpi Rajoria ◽  
Robert Suriano ◽  
Arulkumaran Shanmugam ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Endothelial Progenitor Cell ◽  
Cell Biology ◽  
Progenitor Cell ◽  
Endothelial Progenitor
Sign in / Sign up

Export Citation Format

Share Document