scholarly journals Pulmonary Hypertension in Aortic and Mitral Valve Disease

2018 ◽  
Vol 5 ◽  
Author(s):  
Micha T. Maeder ◽  
Lukas Weber ◽  
Marc Buser ◽  
Marc Gerhard ◽  
Philipp K. Haager ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease

Use of Prostaglandin E1 to Treat Peri-Anaesthetic Pulmonary Hypertension Associated with Mitral Valve Disease

1993 ◽  
Vol 21 (3) ◽  
pp. 161-164 ◽  
Author(s):  
K Mikawa ◽  
N Maekawa ◽  
R Goto ◽  
H Yaku ◽  
K Nishina ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Glyceryl Trinitrate ◽  
Mitral Valve Disease ◽  
Prostaglandin E1 ◽  
Valve Disease ◽  
Prostaglandin E ◽  
Severe Pulmonary Hypertension ◽  
Critical Problem ◽  
Ventricular Afterload

Severe pulmonary hypertension (PH) can be a critical problem during and after cardiac surgery, since it increases right ventricular afterload resulting in decreased cardiac output. A case of pulmonary hypertension associated with mitral valve disease and resistant to glyceryl trinitrate therapy during surgery is reported. The case was treated successfully with prostaglandin E1 (PGE1), indicating that PGE1 can be used peri-operatively in a patient with refractory PH resistant to glyceryl trinitrate treatment.

PADN procedure in patients with mitral valve disease, atrial fibrillation and high pulmonary hypertension

2019 ◽  
Vol 12 (5) ◽  
pp. 450
Author(s):  
N. A. Trofimov ◽  
A. P. Medvedev ◽  
V. E. Babokin ◽  
A. G. Dragunov ◽  
I. P. Efimova ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease

Prognostic Value of Pulmonary Hypertension in Patients Undergoing Surgery for Degenerative Mitral Valve Disease with Leaflet Prolapse

2012 ◽  
Vol 27 (6) ◽  
pp. 668-675 ◽  
Author(s):  
Shahab Nozohoor ◽  
Snejana Hyllén ◽  
Carl Meurling ◽  
Per Wierup ◽  
Johan Sjögren
Keyword(s):  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Prognostic Value ◽  
Valve Disease ◽  
Leaflet Prolapse

scholarly journals Assessment of Platelet and Plasma Serotonin in Canine Pulmonary Hypertension Secondary to Degenerative Mitral Valve Disease

2021 ◽  
Vol 8 ◽  
Author(s):  
Nattawan Tangmahakul ◽  
Pussadee Makoom ◽  
Sirilak Disatian Surachetpong
Keyword(s):  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
High Probability ◽  
Valve Disease ◽  
Serotonin Concentration ◽  
Platelet Serotonin ◽  
The Difference ◽  
Post Hoc ◽  
Plasma Serotonin

Background: Pulmonary hypertension (PH) is a common complication of degenerative mitral valve disease (DMVD), the most common cardiovascular disease in dogs. Serotonin has been suspected to play a role in the pathogenesis of PH, so this study aimed to investigate the differences in platelet and plasma serotonin between normal, DMVD and DMVD with PH (DMVD+PH) dogs.Materials and Methods: Sixty-two small-breed dogs were enrolled to the study and divided into the normal (n = 22), DMVD (n = 20), and DMVD+PH (n = 20) groups. The platelet and plasma serotonin concentrations were measured by the competitive ELISA.Results: The Kruskal–Wallis revealed the difference among the four groups of normal (179.73 [102.37–352.24] ng/109 platelets), DMVD (325.99 [96.84–407.66] ng/109 platelets), DMVD with intermediate probability of PH (291.11 [106.69–400.84] ng/109 platelets) and DMVD with high probability of PH (35.82 [2.69–126.35] ng/109 platelets) (p = 0.014). The Dunn's post-hoc test showed a decrease in the platelet serotonin concentration of the DMVD dogs with high probability of PH compared to the DMVD group (p = 0.008). The plasma serotonin concentration was not different between normal, DMVD, and DMVD+PH dogs.Conclusion: In conclusion, a decrease in platelet serotonin concentration, which is associated with a degree of PH probability was found in DMVD dogs with PH. Further studies investigating roles of platelet serotonin in PH secondary to DMVD should be performed.

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