scholarly journals Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi

2015 ◽  
Vol 5 ◽  
Author(s):  
Haitham A. Yacoub ◽  
Ahmed M. Elazzazy ◽  
Osama A. H. Abuzinadah ◽  
Ahmed M. Al-Hejin ◽  
Maged M. Mahmoud ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Antimicrobial Activities ◽  
Bacteria And Fungi

scholarly journals Antimicrobial Activities of Marine Sponge-Associated Bacteria

2021 ◽  
Vol 9 (1) ◽  
pp. 171
Author(s):  
Yitayal S. Anteneh ◽  
Qi Yang ◽  
Melissa H. Brown ◽  
Christopher M. M. Franco
Keyword(s):  
Pathogenic Bacteria ◽  
South Australia ◽  
Multidrug Resistant ◽  
Antimicrobial Activities ◽  
Marine Sponges ◽  
Bioactive Metabolites ◽  
Human Pathogens ◽  
Sponge Associated Bacteria ◽  
Microbial Symbionts ◽  
Bacteria And Fungi

The misuse and overuse of antibiotics have led to the emergence of multidrug-resistant microorganisms, which decreases the chance of treating those infected with existing antibiotics. This resistance calls for the search of new antimicrobials from prolific producers of novel natural products including marine sponges. Many of the novel active compounds reported from sponges have originated from their microbial symbionts. Therefore, this study aims to screen for bioactive metabolites from bacteria isolated from sponges. Twelve sponge samples were collected from South Australian marine environments and grown on seven isolation media under four incubation conditions; a total of 1234 bacterial isolates were obtained. Of these, 169 bacteria were tested in media optimized for production of antimicrobial metabolites and screened against eleven human pathogens. Seventy bacteria were found to be active against at least one test bacterial or fungal pathogen, while 37% of the tested bacteria showed activity against Staphylococcus aureus including methicillin-resistant strains and antifungal activity was produced by 21% the isolates. A potential novel active compound was purified possessing inhibitory activity against S. aureus. Using 16S rRNA, the strain was identified as Streptomyces sp. Our study highlights that the marine sponges of South Australia are a rich source of abundant and diverse bacteria producing metabolites with antimicrobial activities against human pathogenic bacteria and fungi.

scholarly journals Isolation and Identification of Saccharomyces cerevisiae from Caterpillar Frass and their Probiotic Characterization

2019 ◽  
Vol 16 (1) ◽  
pp. 179-186 ◽  
Author(s):  
Ujwala Vinayak Khisti ◽  
Suyash Arun Kathade ◽  
Mayur Arjun Aswani ◽  
Pashmin Kaur Anand ◽  
Nirichan Kunchirman Bipinraj
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Pathogenic Bacteria ◽  
Antimicrobial Activities ◽  
Yeast Cells ◽  
Isolation And Identification ◽  
Yeast Cultures ◽  
Isolation And Characterization ◽  
Wide Range ◽  
Probiotic Yeast ◽  
Bacteria And Fungi

Probiotics are live microorganisms which upon ingestion confer health benefits to the host and are widely applied for human and animal welfare. The present study reports the isolation of yeast cells from caterpillar frasses and its probiotic characterization. Out of four yeast cultures isolated, all found to be non-hemolytic and cultures designated as CV-I, CV-II CV-III and CV-IV showed good bile tolerance at 1.2%. These cultures possessed the ability to grow pH range of 1.5 – 10, exhibited auto-aggregation and co-aggregation capabilities, which are essential for growth in alimentary canal and reduction of pathogen adherence on the intestinal epithelial cells. All cultures exhibited good tolerance to temperature up to 42°C. Isolate CV-I showed wide range of antimicrobial activities against pathogenic bacteria and fungi. This study is the first report of isolation and characterization of probiotic yeast from caterpillar frass. The isolate CV-I has been identified as Saccharomyces cerevisiae by molecular methods. This culture is an ideal candidate for further probiotic exploration.

In-Vitro Cytotoxicity, Antimicrobial activities and DNA binding studies, of Novel Copper (II) complex with Heterocyclic base

2021 ◽  
pp. 3051-3055
Author(s):  
Shalini V. ◽  
Deepika R. ◽  
Arumugham M. N
Keyword(s):  
Dna Binding ◽  
Pathogenic Bacteria ◽  
Spectroscopic Method ◽  
Antimicrobial Activities ◽  
In Vitro Cytotoxicity ◽  
Binding Studies ◽  
Heterocyclic Base ◽  
Heterocyclic Ligand ◽  
Bacteria And Fungi

A novel ternary copper (II) complex have been synthesized by the addition of N, N-heterocyclic ligand with L-amino acid. The copper (II) complex, [Cu(1,10-phen) (L-Thr) Br] (where phen=1,10-phenanthroline and Threo=Threonine) characterized by various spectroscopic method. The intense UV band around 271nm was due to π-π* transition. The DNA binding study of these copper (II) complex are examined by UV–Visible, Emission spectroscopic, cyclic voltammetric and viscosity method. The results revealed that complex shown to be a intercalation mode of binding into DNA. The anticancer activity of Cu (II) complexes has capability to the kill HepG2 liver cancer cell as assessed by the MTT method, The Ic50value was found 21.50µg/ml The biological activity of the complex tested against certain pathogenic bacteria and fungi results revealed it was found to be potent antibacterial agent.

scholarly journals Novel Synthetic Strategy of Cyclic Dithiocarbamates Catalyzed by Triton-B

2019 ◽  
Vol 31 (5) ◽  
pp. 1091-1094 ◽  
Author(s):  
R. Kishore ◽  
M. Kamboj ◽  
M. Shukla ◽  
N. Srivastava
Keyword(s):  
Pathogenic Bacteria ◽  
Phase Transfer ◽  
Antimicrobial Activities ◽  
Spectroscopic Methods ◽  
Mild Conditions ◽  
Synthetic Strategy ◽  
Green Approach ◽  
Bacteria And Fungi ◽  
Ethyl Bromopyruvate

A simple, rapid and green methodology to synthesize cyclic dithiocarbamates (compounds 1-9) was developed by the reaction of 1° amines, CS2 and ethyl 3-bromo-2-oxopropanoate (ethyl bromopyruvate) facilitated by Triton-B as phase transfer catalyst. These compounds (1-9) were characterized with the help of elemental analysis, IR, NMR and mass spectroscopic methods This efficient green approach requires mild conditions and gives good yield of product. In vitro antimicrobial activities of these compounds are reported against the pathogenic bacteria and fungi.

scholarly journals Antimicrobial activities of isolated probiotics and their metabolites against some pathogenic microorganisms

IIUC Studies ◽  
2018 ◽  
Vol 14 (1) ◽  
pp. 21-28
Author(s):  
Mohammed Abu Sayeed ◽  
Altaf Hossen ◽  
Repon Saha ◽  
Md Jakaria
Keyword(s):  
Pathogenic Bacteria ◽  
Antibacterial Effect ◽  
Antibacterial Property ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Maximum Effect ◽  
Zone Of Inhibition ◽  
Agar Media ◽  
Bacteria And Fungi

The study was aimed to finding the antimicrobial activities among probiotics isolated from different yoghurts and their metabolites against some common bacterial pathogens. The nutrient agar media overlay method (Disc diffusion Method) was used to determine the presence of antibacterial effects among the isolated probiotics. Probiotics produced potential antibacterial activities against several pathogenic bacteria and fungi. The maximum antibacterial property (13.5 mm of zone of inhibition) of bacterial strain found against Salmonella paratyphi. Conversly, bacterial metabolites produced maximum effect (10.3 mm of zone of inhibition) against Staphylocuccos aureaus. The antibacterial effect is one of the most important criteria for probiotics selection, and the verified antibacterial activities of the probiotics supports the development of these functional foods as a key to the enhancement of health in the consuming public.IIUC Studies Vol.14(1) June 2017: 21-28

scholarly journals Antimicrobial and anti-inflammatory activities of commercial aromatizing fragrances

2021 ◽  
pp. FSO704
Author(s):  
Hagar Bach ◽  
Horacio Bach
Keyword(s):  
Antimicrobial Activity ◽  
Inflammatory Response ◽  
Synergistic Effect ◽  
Binary Mixtures ◽  
Vapor Phase ◽  
Pathogenic Bacteria ◽  
Antimicrobial Activities ◽  
New Approach ◽  
Anti Inflammatory ◽  
Bacteria And Fungi

Aim: To explore the bioactivities of commercial fragrances. Materials & methods: The antimicrobial activity of 25 commercial fragrances was assessed with pathogenic bacteria and fungi in vapor phase. Inflammatory response was evaluated by the measurement of cytokines. Results: Several fragrances were able to kill the microorganisms. Moreover, preparations of binary mixtures of the most active fragrances showed a synergistic effect. Regarding the inflammatory response, none of the tested fragrances showed a pro-inflammatory response, but two fragrances upregulated the secretion of IL-10 from macrophages. Conclusion: The antimicrobial activities of fragrances represent a new approach to control airborne pathogens.

scholarly journals Effect of Yttrium Oxide in Hydroxyapatite Biocomposite Materials: Electrical and Antimicrobial Evaluation

2021 ◽  
Author(s):  
G. M. Turky ◽  
Esmat Hamzawy ◽  
Gehan Bassyouny ◽  
Sayed Kenawy ◽  
Abeer A. Abd El-Aty
Keyword(s):  
Yttrium Oxide ◽  
Pathogenic Bacteria ◽  
Chemical Precipitation ◽  
Antimicrobial Activities ◽  
X Rays ◽  
Ionic Radii ◽  
Ft Ir ◽  
Mussel Shells ◽  
Bacteria And Fungi ◽  
Xrd Patterns

Abstract Synthesis and characterization of biocomposite materials of hydroxyapatite (HA) and yttrium oxide (Y2O3) were investigated. HA nanoparticles powder was obtained from mussel shells via a wet chemical precipitation routine. HA powder was doped with 1 and 2 wt% of Y2O3 . For microstructural examination, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and scanning electron microscopy (SEM) coupled with energy dispersive X-rays (EDX) were used. In addition, the dielectric and electrical properties and antimicrobial activities were investigated. XRD patterns reveal the crystallization of the oxyapatite. The peak intensities of pristine HA are inferior compared to the yttrium containing HA composites, thus suggesting that the addition of yttrium promotes the crystallization of HA due to the variance in their ionic radii. FT-IR shows a variation in the phosphate wavenumber, indicating the integration of yttrium into the HA matrix. SEM reveals nanorod- or worm-like crystals arose in clusters. With increasing Y2O3, from 1 to 2 wt%, the DC conductivity reduces from 16 to 9.3 nS/cm, which confirms that high amounts of Y3+ substitute Ca2+ in the HA matrix. In the high-frequency range, the AC conductivity linearly increases with increasing frequency following the universal power law. Further, antimicrobial activity results showed that the addition of yttrium in HA improves the antimicrobial effects against pathogenic bacteria and fungi. Additional research is needed to investigate the doping concentration of yttrium ions, and an anticipated property could be comprehended for several forthcoming biomedical applications

Sign in / Sign up

Export Citation Format

Share Document