scholarly journals Loss of Drosophila E3 Ubiquitin Ligase Hyd Promotes Extra Mitosis in Germline Cysts and Massive Cell Death During Oogenesis

2020 ◽  
Vol 8 ◽  
Author(s):  
Natalia V. Dorogova ◽  
Yuliya A. Galimova ◽  
Elena Us. Bolobolova ◽  
Elina M. Baricheva ◽  
Svetlana A. Fedorova
Keyword(s):  
Cell Death ◽  
Ubiquitin Ligase ◽  
E3 Ubiquitin Ligase ◽  
Massive Cell Death ◽  
Massive Cell

scholarly journals E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin

2014 ◽  
Vol 74 (8) ◽  
pp. 2246-2257 ◽  
Author(s):  
Craig MacKay ◽  
Eilís Carroll ◽  
Adel F.M. Ibrahim ◽  
Amit Garg ◽  
Gareth J. Inman ◽  
...  
Keyword(s):  
Cell Death ◽  
Ubiquitin Ligase ◽  
Apoptotic Cell ◽  
E3 Ubiquitin Ligase ◽  
Apoptotic Cell Death

55Reintroduction of bladder cancer-downregulated miR-145 results in massive cell death of bladder cancer cell lines

Apmis ◽  
2008 ◽  
Vol 116 (5) ◽  
pp. 417-417
Author(s):  
Marie S. Ostenfeld ◽  
Jesper B. Bramsen ◽  
Jørgen Kjems ◽  
Torben Ørntoft ◽  
Lars Dyrskjøt
Keyword(s):  
Bladder Cancer ◽  
Cell Death ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Massive Cell Death ◽  
Massive Cell

scholarly journals Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells

BMC Cancer ◽  
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Ancély F. dos Santos ◽  
Letícia F. Terra ◽  
Rosangela A. M. Wailemann ◽  
Talita C. Oliveira ◽  
Vinícius de Morais Gomes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Methylene Blue ◽  
Cell Death ◽  
Photodynamic Therapy ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Massive Cell Death ◽  
Massive Cell

55 Reintroduction of bladder cancer-downregulated miR-145 results in massive cell death of bladder cancer cell lines

Apmis ◽  
2008 ◽  
Vol 116 (5) ◽  
pp. 417-417
Author(s):  
Marie S. Ostenfeld ◽  
Jesper B. Bramsen ◽  
Jørgen Kjems ◽  
Torben Ørntoft ◽  
Lars Dyrskjøt
Keyword(s):  
Bladder Cancer ◽  
Cell Death ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Massive Cell Death ◽  
Massive Cell

scholarly journals Parkin is an E3 ubiquitin-ligase for normal and mutant ataxin-2 and prevents ataxin-2-induced cell death

2007 ◽  
Vol 203 (2) ◽  
pp. 531-541 ◽  
Author(s):  
Duong P. Huynh ◽  
Dung T. Nguyen ◽  
Johannes B. Pulst-Korenberg ◽  
Alexis Brice ◽  
Stefan-M. Pulst
Keyword(s):  
Cell Death ◽  
Ubiquitin Ligase ◽  
E3 Ubiquitin Ligase ◽  
Ataxin 2

scholarly journals Dexamethasone Treatment Limits Efficacy of Radiation, but Does Not Interfere With Glioma Cell Death Induced by Tumor Treating Fields

2021 ◽  
Vol 11 ◽  
Author(s):  
Benedikt Linder ◽  
Abigail Schiesl ◽  
Martin Voss ◽  
Franz Rödel ◽  
Stephanie Hehlgans ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Lines ◽  
Clinical Analysis ◽  
Concomitant Treatment ◽  
Tumor Treating Fields ◽  
Cell Counts ◽  
Anti Cancer ◽  
Massive Cell Death ◽  
Human Gbm ◽  
Massive Cell

PurposeDexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) patients. Recent studies identified the addition of Dex to radiation therapy (RT) to be associated with poor survival. Independently, Tumor Treating Fields (TTFields) provides a novel anti-cancer modality for patients with primary and recurrent GBM. Whether Dex influences the efficacy of TTFields, however, remains elusive.MethodsHuman GBM cell lines MZ54 and U251 were treated with RT or TTFields in combination with Dex and the effects on cell counts and cell death were determined via flow cytometry. We further performed a retrospective analysis of GBM patients with TTFields treatment +/- concomitant Dex and analysed its impact on progression-free (PFS) and overall survival (OS).ResultsThe addition of Dex significantly reduced the efficacy of RT in U251, but not in MZ54 cells. TTFields (200 kHz/250 kHz) induced massive cell death in both cell lines. Concomitant treatment of TTFields and Dex did not reduce the overall efficacy of TTFields. Further, in our retrospective clinical analysis, we found that the addition of Dex to TTFields therapy did not influence PFS nor OS.ConclusionOur translational investigation indicates that the efficacy of TTFields therapy in patients with GBM and GBM cell lines is not affected by the addition of Dex.

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