scholarly journals Novel Mutations in COL6A3 That Associated With Peters’ Anomaly Caused Abnormal Intracellular Protein Retention and Decreased Cellular Resistance to Oxidative Stress

2020 ◽  
Vol 8 ◽  
Author(s):  
Yue Li ◽  
Jing Zhang ◽  
Yiqin Dai ◽  
Yidan Fan ◽  
Jianjiang Xu
Keyword(s):  
Oxidative Stress ◽  
Intracellular Protein ◽  
Novel Mutations ◽  
Cellular Resistance ◽  
Protein Retention ◽  
Peters Anomaly

scholarly journals The cellular resistance against oxidative stress (H2O2) is independent of neutral trehalase (Ntc1p) activity inCandida albicans

2006 ◽  
Vol 6 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Y. Pedreño ◽  
P. González-Párraga ◽  
S. Conesa ◽  
M. Martínez-Esparza ◽  
A. Aguinaga ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cellular Resistance ◽  
Neutral Trehalase ◽  
Incandida Albicans

scholarly journals In Silico Analysis of B3GALTL Gene Reveling 13 Novel Mutations Associated with Peters’-plus syndrome

2020 ◽  
Author(s):  
Abdelrahman H. Abdelmoneim ◽  
Arwa A. Satti ◽  
Miysaa I. Abdelmageed ◽  
Naseem S. Murshed ◽  
Nafisa M. Elfadol ◽  
...  
Keyword(s):  
In Silico ◽  
Autosomal Recessive ◽  
In Silico Analysis ◽  
Autosomal Recessive Disorder ◽  
Coding Region ◽  
Novel Mutations ◽  
Physiochemical Properties ◽  
Peters Anomaly ◽  
Systemic Manifestations ◽  
Silico Analysis

AbstractBackgroundPeters’-plus syndrome is a rare autosomal recessive disorder, which is characterized by a specific malformation of the eye that includes corneal opaqueness and iridocorneal adhesions (Peters’ anomaly) along with other systemic manifestations. Furthermore, various researches report the association between B3GALTL gene and Peters’-plus syndrome. In the current work we aim to analyze the deleterious SNPs in B3GALTL gene that predispose to Peters’-plus syndrome.Methodthe associated SNPs of the coding region of the B3GALTL gene was acquired from National Center for Biotechnology Information and then analyzed by eight softwares (SIFT, Polyphen2, Proven, SNAP2, SNP@GO, PMut, Imutant and Mupro). The physiochemical properties of the resulted SNPs were then analyzed by Hope project website and visualized by chimera software.ResultThirteen novel mutations (Y172C, A222V, C260R, C260Y, D349G, I354K, R377C, G379C, G393R, G393E, G395E, G425E, R445W) are discovered in B3GALTL gene to cause deleterious effects leading to the development of Peters’-plus syndrome.ConclusionThirteen novel mutations in B3GALTL gene are predicted to cause Peters’-plus syndrome.

scholarly journals The cellular resistance against oxidative stress (H2O2) is independent of neutral trehalase (Ntc1p) activity in Candida albicans

2006 ◽  
Vol 6 (2) ◽  
pp. 319-319 ◽  
Author(s):  
Yolanda Pendreño ◽  
Pilar González-Párraga ◽  
Sergio Conesa ◽  
María Martínez-Esparza ◽  
Ana Aguinaga ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Candida Albicans ◽  
Cellular Resistance ◽  
Neutral Trehalase

scholarly journals Increased cellular resistance to oxidative stress by expression of cyanobacterium catalase-peroxidase in animal cells

FEBS Letters ◽  
1998 ◽  
Vol 426 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Takahiro Ishikawa ◽  
Yuriko Ohta ◽  
Toru Takeda ◽  
Shigeru Shigeoka ◽  
Morimitsu Nishikimi
Keyword(s):  
Oxidative Stress ◽  
Animal Cells ◽  
Cellular Resistance ◽  
Catalase Peroxidase

scholarly journals Nitric Oxide-Induced Cytotoxicity: Involvement of Cellular Resistance to Oxidative Stress and the Role of Glutathione in Protection

1995 ◽  
Vol 37 (1) ◽  
pp. 41-49 ◽  
Author(s):  
M Whit Walker ◽  
Michael T Kinter ◽  
Robert J Roberts ◽  
Douglas R Spitz
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Cellular Resistance
Sign in / Sign up

Export Citation Format

Share Document